Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G000472`

染色体: Chr05 坐标: 3589232-3595866 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G000472`
名称	SmilChr05G000472
描述	phosphoribosylaminoimidazole carboxylase, chloroplastic
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	3589232 - 3595866 / `+`

ID 对照

NCBI Gene ID	`LOC130985195`
GeneID	`130985195`
locus_tag	`-`
NCBI Name	`LOC130985195`
原始查询	`LOC130985195`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	phosphoribosylaminoimidazole carboxylase, chloroplastic
产物	phosphoribosylaminoimidazole carboxylase%2C chloroplastic
Arabidopsis	`AT2G37690` (AT2G37690) phosphoribosylaminoimidazole carboxylase, putative / AIR carboxylase [Source:NCBI gene (formerly Entrezgene);Acc:818346] identity=76.9; qcov=0.923; evalue=0; confidence=high
Rice	`Os01g0199900` (B1046G12.39) - identity=67.6; qcov=0.91; evalue=0; confidence=high
GO	GO:0004638 (phosphoribosylaminoimidazole carboxylase activity); GO:0005524 (ATP binding); GO:0006189 ('de novo' IMP biosynthetic process); GO:0009507 (chloroplast); GO:0046872 (metal ion binding)
KEGG	smil00230 (Purine metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF00731 (AIRC); PF02222 (ATP-grasp); PF02786 (CPSase_L_D2); PF07478 (Dala_Dala_lig_C); PF17769 (PurK_C); PF22660 (RS_preATP-grasp-like)
InterPro	-
eggNOG	-
NR	GeneID:130985195

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057764008.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057764008.1`
3	Nucleus	细胞核	0.00000	`XP_057764008.1`
4	Chromosome	染色体	0.00000	`XP_057764008.1`
5	Centromere	着丝粒	0.00000	`XP_057764008.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:3589871`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B74
`Chr5:3589982`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B21,C41,C44,C74
`Chr5:3590538`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B10,B41,C38
`Chr5:3590899`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C44,C74
`Chr5:3591073`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A20,B3,B95
`Chr5:3593259`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B7,D7
`Chr5:3593276`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A3,B13,D11
`Chr5:3594197`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B64
`Chr5:3594426`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C71
`Chr5:3594613`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B21,C41,C44,C74
`Chr5:3594807`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B73
`Chr5:3594816`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B40,B66

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057764008.1

634 aa

317

634

RS_preATP-grasp-like

CPSase_L_D2

ATP-grasp

Dala_Dala_lig_C

PurK_C

AIRC

PF22660 RS_preATP-grasp-like 82-178 aa PF02786 CPSase_L_D2 184-349 aa PF02222 ATP-grasp 186-364 aa PF07478 Dala_Dala_lig_C 206-348 aa PF17769 PurK_C 386-448 aa PF00731 AIRC 468-613 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057764008.1`	Pfam	`PF22660`	RS_preATP-grasp-like	Domain	82	178	5.3e-30	104.4	Ribonucleotide synthetase preATP-grasp domain
`XP_057764008.1`	Pfam	`PF02786`	CPSase_L_D2	Domain	184	349	7.1e-07	29.7	Carbamoyl-phosphate synthase L chain, ATP binding domain
`XP_057764008.1`	Pfam	`PF02222`	ATP-grasp	Domain	186	364	1.2e-62	211.5	ATP-grasp domain
`XP_057764008.1`	Pfam	`PF07478`	Dala_Dala_lig_C	Family	206	348	3.8e-09	37.1	D-ala D-ala ligase C-terminus
`XP_057764008.1`	Pfam	`PF17769`	PurK_C	Domain	386	448	5.6e-18	65.1	Phosphoribosylaminoimidazole carboxylase C-terminal domain
`XP_057764008.1`	Pfam	`PF00731`	AIRC	Domain	468	613	2.1e-67	226.0	AIR carboxylase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057908025.1
AAAAAAGCCCAAACAACATTCTGTCTTTTCTTCTTGCTATCGTCTCTGCCGCTCTTTCTCACTCTCTCTCTCTGCCGTTATCTCTCTTCGCCGCCGCCGCCGCTCCCACCTTCTCCGATAGCCCGTGGCCACGGCCTCGCCGCCTCGGAGCTCTCCAGCAAACAGCAGTAGTTCGCGACCTCGTCTAGCATTCCCCGTCACCTTCAACCTCGGCGCCTCCGTCCGGTGACTCCGTAGAACCAGGTTTCGACGCCAAATTC...

CDS

1 records

下载 CDS FASTA

LOC130985195
ATGCAGAGCCTGAATGCTTTATTTGAAAGCTCAGCAGCAATCACGTCAGCTGCAACTTCATTAGCTTTCTTGAATCCTAACAAAGCTGCAGTTTACAGGAGCACTTTTGTTCCAACGAACATCGGCATGAAGGCGTTGAGGAACACAGCGCTTAGAGCTTCTTCGGCTCATTGTAGAGCTTCTTTGGAAGTTCAAGATTCGTCTCCTGGCACTGAGGTACCAGTCCATGGGTTGTCGGAAACAGTTGTGGGCATTCTTGG...

Protein

1 records

下载 Protein FASTA

XP_057764008.1
MQSLNALFESSAAITSAATSLAFLNPNKAAVYRSTFVPTNIGMKALRNTALRASSAHCRASLEVQDSSPGTEVPVHGLSETVVGILGGGQLGRMLCEAASQLAIKVVILDPMENCPASNLCHYHMVGSYDDSATVEAFAKICGVLTVEIEHVDAATLEKLEEQGVDCQPKASTIRIIQDKYLQKVHFSEHSIPLPEFMQIDDLEGSKRAAELFGYPLMIKSKRLAYDGRGNAVAKNEDEISSAVNALGGYARGLYVEKWA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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