Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G000858`

染色体: Chr05 坐标: 6776998-6782718 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G000858`
名称	SmilChr05G000858
描述	phosphatidylinositol 3-kinase, root isoform
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	6776998 - 6782718 / `-`

ID 对照

NCBI Gene ID	`LOC130985568`
GeneID	`130985568`
locus_tag	`-`
NCBI Name	`LOC130985568`
原始查询	`LOC130985568`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	phosphatidylinositol 3-kinase, root isoform
产物	phosphatidylinositol 3-kinase%2C root isoform
Arabidopsis	`AT1G60490` (VPS34) vacuolar protein sorting 34 [Source:NCBI gene (formerly Entrezgene);Acc:842344] identity=83.7; qcov=1; evalue=0; confidence=high
Rice	`Os05g0180600` - identity=75.6; qcov=1; evalue=0; confidence=high
GO	GO:0000045 (autophagosome assembly); GO:0000407 (phagophore assembly site); GO:0005737 (cytoplasm); GO:0005768 (endosome); GO:0005777 (peroxisome); GO:0006897 (endocytosis); GO:0016020 (membrane); GO:0016303 (1-phosphatidylinositol-3-kinase activity); GO:0030242 (autophagy of peroxisome); GO:0034271 (phosphatidylinositol 3-kinase complex, class III, type I); GO:0034272 (phosphatidylinositol 3-kinase complex, class III, type II); GO:0036092 (phosphatidylinositol-3-phosphate biosynthetic process); GO:0048015 (phosphatidylinositol-mediated signaling)
KEGG	smil00562 (Inositol phosphate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil04070 (Phosphatidylinositol signaling system - Salvia miltiorrhiza (redroot sage)); smil04136 (Autophagy - other - Salvia miltiorrhiza (redroot sage)); smil04145 (Phagocytosis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00454 (PI3_PI4_kinase); PF00613 (PI3Ka); PF00792 (PI3K_C2)
InterPro	-
eggNOG	-
NR	GeneID:130985568

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057764591.1`
2	Cytosol	细胞质基质	1.00000	`XP_057764591.1`
3	Vesicle	囊泡	0.80000	`XP_057764591.1`
4	Trans-golgi network	Trans-golgi network	0.60000	`XP_057764591.1`
5	Golgi apparatus	高尔基体	0.40000	`XP_057764591.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:6777549`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C27
`Chr5:6777754`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A18,C43
`Chr5:6777760`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C5
`Chr5:6777823`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C27
`Chr5:6778304`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B72
`Chr5:6778365`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B108,B120,B76,C53
`Chr5:6778366`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C61
`Chr5:6778618`	`AG`	`A`	1bp_deletion	frameshift_variant	3	B81,B87,C44
`Chr5:6778618`	`AG`	`A`	1bp_deletion	CDS_variant	3	B81,B87,C44
`Chr5:6778621`	`TG`	`T`	1bp_deletion	frameshift_variant	3	B81,B87,C44
`Chr5:6778621`	`TG`	`T`	1bp_deletion	CDS_variant	3	B81,B87,C44
`Chr5:6778624`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B81,B87,C14,C44

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057764591.1

815 aa

408

815

PI3K_C2

PI3Ka

PI3_PI4_kinase

PF00792 PI3K_C2 48-191 aa PF00613 PI3Ka 277-451 aa PF00454 PI3_PI4_kinase 560-761 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057764591.1`	Pfam	`PF00792`	PI3K_C2	Domain	48	191	9.4e-43	146.2	Phosphoinositide 3-kinase C2
`XP_057764591.1`	Pfam	`PF00613`	PI3Ka	Repeat	277	451	7e-64	215.4	Phosphoinositide 3-kinase family, accessory domain (PIK domain)
`XP_057764591.1`	Pfam	`PF00454`	PI3_PI4_kinase	Family	560	761	3e-60	204.9	Phosphatidylinositol 3- and 4-kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XR_009088997.1
TAGCTAATTTTCACAATTTTGAGTGAAATATGTGGAAAAATTGGAAAATTTTACCAATTCGAAAAACTCACTGAAATTCATCGCAGGAGAAAGAGAAAGGCGATGACCGGGAACGAATTCCGATTCTTCTTGTCGTGTGACATTAATCTGCCGGTGACTTTCAAAATCGAGAGATTGGAGGGCAAGTTATCTGCTCGGAAACCTCCCGATTCAGAGGACAAGAAACCCGAGTTGTACGTTGAAAGCTTGTTGTACATCGA...

XR_009088996.1
TAGCTAATTTTCACAATTTTGAGTGAAATATGTGGAAAAATTGGAAAATTTTACCAATTCGAAAAACTCACTGAAATTCATCGCAGGAGAAAGAGAAAGGCGATGACCGGGAACGAATTCCGATTCTTCTTGTCGTGTGACATTAATCTGCCGGTGACTTTCAAAATCGAGAGATTGGAGGGCAAGTTATCTGCTCGGAAACCTCCCGATTCAGCTGATGGTGATTGTACCATAGAGGACAAGAAACCCGAGTTGTACGT...

CDS

1 records

下载 CDS FASTA

LOC130985568
ATGACCGGGAACGAATTCCGATTCTTCTTGTCGTGTGACATTAATCTGCCGGTGACTTTCAAAATCGAGAGATTGGAGGGCAAGTTATCTGCTCGGAAACCTCCCGATTCAGCTGATGGTGATTGTACCATAGAGGACAAGAAACCCGAGTTGTACGTTGAAAGCTTGTTGTACATCGATGGCGCGCCTTTTGGGCTCCCTATGAGAACAAGGTTGGAATCAGGAGGTCCGTCGTATTGTTGGAATGAACTCATCACACT...

Protein

1 records

下载 Protein FASTA

XP_057764591.1
MTGNEFRFFLSCDINLPVTFKIERLEGKLSARKPPDSADGDCTIEDKKPELYVESLLYIDGAPFGLPMRTRLESGGPSYCWNELITLSTKYRDLTANSQLAVTVYDVSCGKDEEVVGGATIHLFNMKKQLKTGKHKLRLWAGKEADGSINTSTPGKVPKEERGELERLEKLVNKYERGQIQRVDWLDRLAFKAMERIKERESLKNGSSHLYVVIDFCSFEHRVVFQESGANFLIPSPIASTNELVTVWDPEVGKINPSEH...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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