Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G001469`

染色体: Chr05 坐标: 13463651-13480714 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G001469`
名称	SmilChr05G001469
描述	E3 ubiquitin-protein ligase UPL1-like
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	13463651 - 13480714 / `-`

ID 对照

NCBI Gene ID	`LOC130986158`
GeneID	`130986158`
locus_tag	`-`
NCBI Name	`LOC130986158`
原始查询	`LOC130986158`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	E3 ubiquitin-protein ligase UPL1-like
产物	E3 ubiquitin-protein ligase UPL1-like
Arabidopsis	`AT1G55860` (UPL1) LOW protein: E3 ubiquitin ligase-like protein [Source:NCBI gene (formerly Entrezgene);Acc:842036] identity=62.6; qcov=1.02; evalue=0; confidence=high
Rice	`Os09g0252800` - identity=58.5; qcov=0.385; evalue=0; confidence=low
GO	GO:0000209 (protein polyubiquitination); GO:0004842 (ubiquitin-protein transferase activity); GO:0005515 (protein binding); GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process); GO:0045732 (positive regulation of protein catabolic process)
KEGG	smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00627 (UBA); PF00632 (HECT); PF06012 (DUF908); PF06025 (DUF913); PF14377 (UBM); PF22562 (UBA_7)
InterPro	-
eggNOG	-
NR	GeneID:130986158

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057765434.1`
2	Cytoplasm	细胞质	0.20000	`XP_057765434.1`
3	Chromosome	染色体	0.00000	`XP_057765434.1`
4	Centromere	着丝粒	0.00000	`XP_057765434.1`
5	Chromatin	染色质	0.00000	`XP_057765434.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:13464943`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B75,C39,C53,C75,C87
`Chr5:13465001`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B41,C22,C9
`Chr5:13465030`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B63,C17
`Chr5:13465043`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B15,C46
`Chr5:13465233`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A25
`Chr5:13465265`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A16,B104,B61,C21,C24
`Chr5:13465317`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B106,C13
`Chr5:13465361`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B8,C39
`Chr5:13465565`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A16
`Chr5:13465957`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B1,B2,D1
`Chr5:13466032`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B22,B65,B91
`Chr5:13466401`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B22,B65,B91

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057765434.1

3738 aa

1869

3738

DUF908

DUF913

UBA

UBA_7

UBM

HECT

PF06012 DUF908 85-140 aa PF06012 DUF908 202-362 aa PF06025 DUF913 422-795 aa PF00627 UBA 1300-1337 aa PF22562 UBA_7 1301-1345 aa PF14377 UBM 2629-2658 aa PF14377 UBM 2668-2698 aa PF14377 UBM 2703-2735 aa PF00632 HECT 3427-3737 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057765434.1`	Pfam	`PF06012`	DUF908	Family	85	140	5.8e-42	145.1	Domain of Unknown Function (DUF908)
`XP_057765434.1`	Pfam	`PF06012`	DUF908	Family	202	362	5.8e-42	145.1	Domain of Unknown Function (DUF908)
`XP_057765434.1`	Pfam	`PF06025`	DUF913	Family	422	795	1.1e-90	305.2	Domain of Unknown Function (DUF913)
`XP_057765434.1`	Pfam	`PF00627`	UBA	Domain	1300	1337	1.9e-08	34.7	UBA/TS-N domain
`XP_057765434.1`	Pfam	`PF22562`	UBA_7	Domain	1301	1345	1.1e-14	54.8	UBA-like domain
`XP_057765434.1`	Pfam	`PF14377`	UBM	Motif	2629	2658	1.8e-30	104.1	Ubiquitin binding region
`XP_057765434.1`	Pfam	`PF14377`	UBM	Motif	2668	2698	1.8e-30	104.1	Ubiquitin binding region
`XP_057765434.1`	Pfam	`PF14377`	UBM	Motif	2703	2735	1.8e-30	104.1	Ubiquitin binding region
`XP_057765434.1`	Pfam	`PF00632`	HECT	Domain	3427	3737	9.2e-96	321.8	HECT-domain (ubiquitin-transferase)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XR_009089186.1
CACCAGCGTAATTTTTCCCCTTTTTTTCCTTTGTCTACAATTCTATGCGATCACCAATTGCCCAGAAAAACCCTCTCTTCGAAAACCCTAGGAATTCACGATCTTTATTCTCCGTAGATACACAATTTCCTCTATCTATCCTGTTCAAATTTTGTGTCTTTTTTCCCAAATCCATCGAATTTCAGCCCTCCGATCCTCGGGTTATCCCATTATTCACTTGAGTTCTCACATACCCCTCCGTCGCTCTATTCAATTTCTCG...

XR_009089185.1
CACCAGCGTAATTTTTCCCCTTTTTTTCCTTTGTCTACAATTCTATGCGATCACCAATTGCCCAGAAAAACCCTCTCTTCGAAAACCCTAGGAATTCACGATCTTTATTCTCCGTAGATACACAATTTCCTCTATCTATCCTGTTCAAATTTTGTGTCTTTTTTCCCAAATCCATCGAATTTCAGCCCTCCGATCCTCGGGTTATCCCATTATTCACTTGAGTTCTCACATACCCCTCCGTCGCTCTATTCAATTTCTCG...

CDS

1 records

下载 CDS FASTA

LOC130986158
ATGAAGTTGAAGCGAAGGAGGGCGCTTGAAGTGCCTTTGAAGATTAAATCCTTCATCAACAATGTTACTGCTACACCCCTGGAGAAAATAGAGGAACCGCTTAAAAATTTTTCTTGGGAGTTTGATAAGGGCGATTTCCATCATTGGGTCGACTTATTTAATCACTTCGACACCTTTTTTGAGAAATTTATTAAACCAAGGAAGGATTTGCAACTTGAGGACAACTTTTTAGAATCAGATCCGCCGTTTCCACGGGATGC...

Protein

1 records

下载 Protein FASTA

XP_057765434.1
MKLKRRRALEVPLKIKSFINNVTATPLEKIEEPLKNFSWEFDKGDFHHWVDLFNHFDTFFEKFIKPRKDLQLEDNFLESDPPFPRDAVLQILRVIRVILENCTNKHFYSSYEHHLSSLLASTDADVVEACLQTLAAFLKKSIGKYIIRDVSLNSRLFSFAQGWGGKEEGLGLIPCALQNISDPIALELGSTLHFEFYSVNEASVEPTSTEQTTRGLQVIHMPDVNARKESDLELLNKLVVEYKVPHNLRFSLLTRLRFAR...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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