Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr05G002142`

染色体: Chr05 坐标: 22581052-22593255 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr05G002142`
名称	SmilChr05G002142
描述	pleiotropic drug resistance protein 1-like
染色体 / SeqID	Chr05 / NC_080391.1
坐标与链方向	22581052 - 22593255 / `-`

ID 对照

NCBI Gene ID	`LOC130986761`
GeneID	`130986761`
locus_tag	`-`
NCBI Name	`LOC130986761`
原始查询	`LOC130986761`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	pleiotropic drug resistance protein 1-like
产物	pleiotropic drug resistance protein 1-like
Arabidopsis	`AT1G15520` (ABCG40) pleiotropic drug resistance 12 [Source:NCBI gene (formerly Entrezgene);Acc:838122] identity=66.5; qcov=0.999; evalue=0; confidence=high
Rice	`Os01g0609300` (OsPDR9) - identity=65.9; qcov=1.01; evalue=0; confidence=high
GO	GO:0005524 (ATP binding); GO:0016020 (membrane); GO:0016887 (ATP hydrolysis activity); GO:0140359 (ABC-type transporter activity)
KEGG	smil02010 (ABC transporters - Salvia miltiorrhiza (redroot sage))
Pfam	PF00005 (ABC_tran); PF01061 (ABC2_membrane); PF08370 (PDR_assoc); PF14510 (ABC_trans_N); PF19055 (ABC2_membrane_7)
InterPro	-
eggNOG	-
NR	GeneID:130986761

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057766257.1`
2	Nucleus	细胞核	0.00000	`XP_057766257.1`
3	Chromosome	染色体	0.00000	`XP_057766257.1`
4	Centromere	着丝粒	0.00000	`XP_057766257.1`
5	Chromatin	染色质	0.00000	`XP_057766257.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr5:22581187`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C40
`Chr5:22581321`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B42,B43
`Chr5:22581927`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B26,B61,B8
`Chr5:22582010`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B26,B61,B8
`Chr5:22582624`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B42,B43
`Chr5:22586364`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B131
`Chr5:22586667`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B131
`Chr5:22586739`	`ATT`	`A`	2bp_deletion	frameshift_variant	48	A10,A13,A14,A16,A18,A2,A20,A7,B100,B103,B104,B105,B106,B109,B11,B117,B119,B120,B122,B126,B137,B19,B22,B3,B31,B35,B51,B52,B64,B73,B76,B78,B82,B85,B97,C12,C36,C41,C46,C5,C60,C67,C76,C83,C86,D10,D5,D9
`Chr5:22586746`	`C`	`CTG`	2bp_insertion	frameshift_variant	44	A13,A14,A16,A18,A2,A20,A7,B100,B103,B104,B105,B106,B109,B11,B117,B119,B120,B122,B126,B137,B19,B22,B3,B31,B35,B51,B52,B64,B73,B76,B78,B82,B85,B97,C12,C36,C41,C46,C60,C67,C76,C86,D5,D9
`Chr5:22586747`	`C`	`CA`	1bp_insertion	frameshift_variant	43	A13,A14,A16,A18,A2,A20,A7,B100,B103,B105,B106,B109,B11,B117,B119,B120,B122,B126,B137,B19,B22,B3,B31,B35,B51,B52,B64,B73,B76,B78,B82,B85,B97,C12,C36,C41,C46,C60,C67,C76,C86,D5,D9
`Chr5:22586749`	`G`	`GTT`	2bp_insertion	frameshift_variant	42	A13,A16,A18,A2,A20,A7,B100,B103,B104,B105,B106,B109,B11,B117,B119,B120,B122,B126,B137,B19,B22,B3,B31,B35,B51,B52,B64,B73,B76,B78,B82,B85,B97,C12,C36,C41,C60,C67,C76,C86,D5,D9
`Chr5:22586751`	`CAA`	`C`	2bp_deletion	frameshift_variant	18	A16,A20,B103,B104,B105,B11,B117,B120,B126,B22,B3,B51,B52,B78,B82,C67,D5,D9

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057766257.1

1421 aa

710

1421

ABC_trans_N

ABC_tran

ABC2_membrane_7

ABC2_membrane

PDR_assoc

ABC_tran

ABC2_membrane

PF14510 ABC_trans_N 89-139 aa PF00005 ABC_tran 164-345 aa PF19055 ABC2_membrane_7 379-429 aa PF01061 ABC2_membrane 501-712 aa PF08370 PDR_assoc 717-779 aa PF00005 ABC_tran 852-1004 aa PF01061 ABC2_membrane 1150-1363 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057766257.1`	Pfam	`PF14510`	ABC_trans_N	Domain	89	139	1.2e-06	29.5	ABC-transporter N-terminal
`XP_057766257.1`	Pfam	`PF00005`	ABC_tran	Domain	164	345	4.9e-40	138.0	ABC transporter
`XP_057766257.1`	Pfam	`PF19055`	ABC2_membrane_7	Family	379	429	3.4e-13	50.0	ABC-2 type transporter
`XP_057766257.1`	Pfam	`PF01061`	ABC2_membrane	Domain	501	712	1.9e-103	345.2	ABC-2 type transporter
`XP_057766257.1`	Pfam	`PF08370`	PDR_assoc	Family	717	779	1.6e-28	99.0	Plant PDR ABC transporter associated
`XP_057766257.1`	Pfam	`PF00005`	ABC_tran	Domain	852	1004	4.9e-40	138.0	ABC transporter
`XP_057766257.1`	Pfam	`PF01061`	ABC2_membrane	Domain	1150	1363	1.9e-103	345.2	ABC-2 type transporter

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057910274.1
TACAGATACGTATATATCGCAATGATAGTAAAAGTGAAAAGTTTTGAAGGCAAAGAATGGAAGAAGGTAGCAGAAACAGCAGCGGGCGTCGGAACATGTGGAGGAACGCCGCCGGGTCGGAGATATTTTCGTGGTCGAGTCGTGAACGGGACGACGAAGAGGCGCTGATCTGGGCAGCGCTGGAGAGACTCCCGACGCGTGCGCGTATAAGGAAAGGCGTCTACTCGGAAGAGAAAGGCGGCGATGCCAGAGAGGTTGAT...

CDS

1 records

下载 CDS FASTA

LOC130986761
ATGGAAGAAGGTAGCAGAAACAGCAGCGGGCGTCGGAACATGTGGAGGAACGCCGCCGGGTCGGAGATATTTTCGTGGTCGAGTCGTGAACGGGACGACGAAGAGGCGCTGATCTGGGCAGCGCTGGAGAGACTCCCGACGCGTGCGCGTATAAGGAAAGGCGTCTACTCGGAAGAGAAAGGCGGCGATGCCAGAGAGGTTGATGTGATGAATCTTGGATTCGCAGAGAGGAAAAATCTTATTGATAGGCTGCTCGACAT...

Protein

1 records

下载 Protein FASTA

XP_057766257.1
MEEGSRNSSGRRNMWRNAAGSEIFSWSSRERDDEEALIWAALERLPTRARIRKGVYSEEKGGDAREVDVMNLGFAERKNLIDRLLDIAHQDNEVFLLKMKRRIDRVGINLPTVEVRFEKMSVDALTYVGTRALPTLPNFAANTFEGLLTKLHILPSRKKPLSVLHDLNGIIRAGRMTLLLGPPTSGKTTLLTALAGKLDQDLQLRGKITYNGHEMDEFIPQRTSAYIGQQDLHLGELTVRETLAYSARCQGVGTAYEMLA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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