Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G002801`

染色体: Chr01 坐标: 46496287-46498198 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G002801`
名称	SmilChr01G002801
描述	mitogen-activated protein kinase kinase 2-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	46496287 - 46498198 / `-`

ID 对照

NCBI Gene ID	`LOC130987027`
GeneID	`130987027`
locus_tag	`-`
NCBI Name	`LOC130987027`
原始查询	`LOC130987027`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	mitogen-activated protein kinase kinase 2-like
产物	mitogen-activated protein kinase kinase 2-like
Arabidopsis	`AT4G29810` (MKK2) MAP kinase kinase 2 [Source:NCBI gene (formerly Entrezgene);Acc:829103] identity=64.8; qcov=0.925; evalue=5.35e-142; confidence=high
Rice	`Os06g0147800` (OsMKK1) - identity=63.6; qcov=0.922; evalue=3.98e-136; confidence=high
GO	GO:0000165 (MAPK cascade); GO:0004674 (protein serine/threonine kinase activity); GO:0004708 (MAP kinase kinase activity); GO:0005524 (ATP binding); GO:0005737 (cytoplasm); GO:0006468 (protein phosphorylation)
KEGG	smil04016 (MAPK signaling pathway - plant - Salvia miltiorrhiza (redroot sage))
Pfam	PF00069 (Pkinase); PF03109 (ABC1); PF07714 (PK_Tyr_Ser-Thr); PF17667 (Pkinase_fungal)
InterPro	-
eggNOG	-
NR	GeneID:130987027

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057766573.1`
2	Nucleus	细胞核	1.00000	`XP_057766582.1`
3	Cytosol	细胞质基质	0.20000	`XP_057766582.1`
4	Chromosome	染色体	0.00000	`XP_057766573.1`
5	Centromere	着丝粒	0.00000	`XP_057766573.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:46496596`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A23,B22,B41
`Chr1:46497029`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B114
`Chr1:46497966`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B11,B114,B133,B64

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057766573.1

367 aa

184

367

Pkinase

PK_Tyr_Ser-Thr

ABC1

Pkinase_fungal

PF00069 Pkinase 84-343 aa PF07714 PK_Tyr_Ser-Thr 86-338 aa PF03109 ABC1 156-233 aa PF17667 Pkinase_fungal 187-271 aa

XP_057766582.1

322 aa

161

322

Pkinase

PK_Tyr_Ser-Thr

ABC1

Pkinase_fungal

PF00069 Pkinase 39-298 aa PF07714 PK_Tyr_Ser-Thr 41-293 aa PF03109 ABC1 111-188 aa PF17667 Pkinase_fungal 142-226 aa

XP_057766589.1

322 aa

161

322

Pkinase

PK_Tyr_Ser-Thr

ABC1

Pkinase_fungal

PF00069 Pkinase 39-298 aa PF07714 PK_Tyr_Ser-Thr 41-293 aa PF03109 ABC1 111-188 aa PF17667 Pkinase_fungal 142-226 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057766573.1`	Pfam	`PF00069`	Pkinase	Domain	84	343	1.2e-70	238.6	Protein kinase domain
`XP_057766573.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	86	338	1.6e-39	136.5	Protein tyrosine and serine/threonine kinase
`XP_057766573.1`	Pfam	`PF03109`	ABC1	Domain	156	233	4.3e-06	26.8	ABC1 atypical kinase-like domain
`XP_057766573.1`	Pfam	`PF17667`	Pkinase_fungal	Domain	187	271	2.3e-06	27.3	Fungal protein kinase
`XP_057766582.1`	Pfam	`PF00069`	Pkinase	Domain	39	298	8.1e-71	239.2	Protein kinase domain
`XP_057766582.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	41	293	1.1e-39	137.1	Protein tyrosine and serine/threonine kinase
`XP_057766582.1`	Pfam	`PF03109`	ABC1	Domain	111	188	3.4e-06	27.1	ABC1 atypical kinase-like domain
`XP_057766582.1`	Pfam	`PF17667`	Pkinase_fungal	Domain	142	226	1.9e-06	27.6	Fungal protein kinase
`XP_057766589.1`	Pfam	`PF00069`	Pkinase	Domain	39	298	8.1e-71	239.2	Protein kinase domain
`XP_057766589.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	41	293	1.1e-39	137.1	Protein tyrosine and serine/threonine kinase
`XP_057766589.1`	Pfam	`PF03109`	ABC1	Domain	111	188	3.4e-06	27.1	ABC1 atypical kinase-like domain
`XP_057766589.1`	Pfam	`PF17667`	Pkinase_fungal	Domain	142	226	1.9e-06	27.6	Fungal protein kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057910590.1
TGTGTGTGTGGCCAATAGGGAGCTAGTAAACATGATAATTGAGGCCCCATTATTTATAACCACCATGGTGTTGGAATTATTGGGTTTACTCACAAAGACTTCCTATTCCTACAATCTCAGATTTGCTCTACACCAAAATGGAGCACCTACCTAAACAGGAAAAGCAAGAAACCAAAATGAACAAGGGGCCTCTAGCTCCCTCCCTCAAGCTCTCTCTCCCTCCCCCCGATCAGTCTTCTCTCTCTAAATTCCTGACCAAG...

XM_057910599.1
CCATGGTGTTGGAATTATTGGGTTTACTCACAAAGACTTCCTATTCCTACAATCTCAGATTTGCTCTACACCAAAATGGAGCACCTACCTAAACAGGAAAAGCAAGAAACCAAAATGAACAAGGGGCCTCTAGCTCCCTCCCTCAAGCTCTCTCTCCCTCCCCCCGATCAGTCTTCTCTCTCTAAATTCCTGTACTCTATCGCTGTCGTTGATGATGATCGATACATGTAATCGGCTTGCTTTTCTTAATTTCTCGTGAT...

CDS

3 records

下载 CDS FASTA

LOC130987027
ATGGAGCACCTACCTAAACAGGAAAAGCAAGAAACCAAAATGAACAAGGGGCCTCTAGCTCCCTCCCTCAAGCTCTCTCTCCCTCCCCCCGATCAGTCTTCTCTCTCTAAATTCCTGACCAAGTCTGGGACTTTTGAGGATGGCGATCTGTTGGTTAACAAAGATGGAGTCCAAGTTGTGTCCCAGAATGAAGTCCAAACTTCAACATTAATTCAGCCATCAGATGACCAGTTGAGCTTAGCAGACTTCGATGTTGTTCG...

LOC130987027
ATGGCGATCTGTTGGTTAACAAAGATGGAGTCCAAGTTGTGTCCCAGAATGAAGTCCAAACTGTATTCAACATTAATTCAGCCATCAGATGACCAGTTGAGCTTAGCAGACTTCGATGTTGTTCGAGTCATCGGTAAAGGGAATGGTGGCATTGTGCACTTGGTACAACATAAATGGACACCCCAATTTTTTGCTCTCAAGGTTATTCAAACCAACGTAGAAGAGTCTACTCGAAAACATATAGAGCGAGAACTCAAAAT...

Protein

3 records

下载 Protein FASTA

XP_057766573.1
MEHLPKQEKQETKMNKGPLAPSLKLSLPPPDQSSLSKFLTKSGTFEDGDLLVNKDGVQVVSQNEVQTSTLIQPSDDQLSLADFDVVRVIGKGNGGIVHLVQHKWTPQFFALKVIQTNVEESTRKHIERELKINQSATQSPYIVVCYQSFYDNGSIYIILEYMDGGSLADFLKKVNMIPEPYLAAICKQVLKGLWYLHNKKRIIHRDLKPSNLLINHRGEVKITDFGVSKILDSTSSVADTFTGTYVYMSPERISGGKYGY...

XP_057766582.1
MAICWLTKMESKLCPRMKSKLYSTLIQPSDDQLSLADFDVVRVIGKGNGGIVHLVQHKWTPQFFALKVIQTNVEESTRKHIERELKINQSATQSPYIVVCYQSFYDNGSIYIILEYMDGGSLADFLKKVNMIPEPYLAAICKQVLKGLWYLHNKKRIIHRDLKPSNLLINHRGEVKITDFGVSKILDSTSSVADTFTGTYVYMSPERISGGKYGYKSDIWSLGLVLLECATGQFPFSPPQAGGWPNFYDLMNTIVDQPAP...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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