Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G003029`

染色体: Chr01 坐标: 49346069-49350693 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G003029`
名称	SmilChr01G003029
描述	arogenate dehydrogenase 2, chloroplastic-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	49346069 - 49350693 / `+`

ID 对照

NCBI Gene ID	`LOC130989248`
GeneID	`130989248`
locus_tag	`-`
NCBI Name	`LOC130989248`
原始查询	`LOC130989248`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	arogenate dehydrogenase 2, chloroplastic-like
产物	arogenate dehydrogenase 2%2C chloroplastic-like
Arabidopsis	`AT1G15710` (AT1G15710) prephenate dehydrogenase family protein [Source:NCBI gene (formerly Entrezgene);Acc:838140] identity=72; qcov=0.798; evalue=6.83e-160; confidence=high
Rice	`Os06g0708832` - identity=65.7; qcov=0.817; evalue=1.17e-145; confidence=high
GO	GO:0004665 (prephenate dehydrogenase (NADP+) activity); GO:0006571 (L-tyrosine biosynthetic process); GO:0008977 (prephenate dehydrogenase (NAD+) activity); GO:0033730 (arogenate dehydrogenase (NADP+) activity)
KEGG	smil00400 (Phenylalanine, tyrosine and tryptophan biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF02153 (PDH_N); PF03446 (NAD_binding_2); PF03807 (F420_oxidored); PF26213 (TYRAAT1_C)
InterPro	-
eggNOG	-
NR	GeneID:130989248

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057769190.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057769190.1`
3	Nucleus	细胞核	0.00000	`XP_057769190.1`
4	Chromosome	染色体	0.00000	`XP_057769190.1`
5	Centromere	着丝粒	0.00000	`XP_057769190.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:49346352`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B40,C52
`Chr1:49346406`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B108,C23,D11
`Chr1:49346648`	`AC`	`A`	1bp_deletion	frameshift_variant	7	A5,B19,B34,C29,C53,C61,C78
`Chr1:49346836`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B49,B78,C39,D7
`Chr1:49346949`	`G`	`GA`	1bp_insertion	frameshift_variant	15	A13,A20,B10,B100,B12,B17,B54,B58,B76,B95,C23,C69,C78,C83,D6
`Chr1:49346954`	`A`	`AC`	1bp_insertion	frameshift_variant	15	A13,A20,B10,B100,B12,B17,B54,B58,B95,C23,C68,C69,C78,C83,D6
`Chr1:49346957`	`TGC`	`T`	2bp_deletion	frameshift_variant	16	A13,A20,B10,B100,B12,B17,B54,B58,B76,B95,C23,C68,C69,C78,C83,D6
`Chr1:49347276`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C60
`Chr1:49347370`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B101

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057769190.1

367 aa

184

367

NAD_binding_2

F420_oxidored

PDH_N

TYRAAT1_C

PF03446 NAD_binding_2 77-165 aa PF03807 F420_oxidored 77-166 aa PF02153 PDH_N 90-200 aa PF26213 TYRAAT1_C 263-336 aa

XP_057769198.1

367 aa

184

367

NAD_binding_2

F420_oxidored

PDH_N

TYRAAT1_C

PF03446 NAD_binding_2 77-165 aa PF03807 F420_oxidored 77-166 aa PF02153 PDH_N 90-200 aa PF26213 TYRAAT1_C 263-336 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057769190.1`	Pfam	`PF03446`	NAD_binding_2	Domain	77	165	1.5e-05	25.8	NAD binding domain of 6-phosphogluconate dehydrogenase
`XP_057769190.1`	Pfam	`PF03807`	F420_oxidored	Family	77	166	4.5e-11	43.9	NADP oxidoreductase coenzyme F420-dependent
`XP_057769190.1`	Pfam	`PF02153`	PDH_N	Domain	90	200	2.3e-09	37.6	Prephenate dehydrogenase, nucleotide-binding domain
`XP_057769190.1`	Pfam	`PF26213`	TYRAAT1_C	Domain	263	336	6.1e-36	122.7	TYRAAT1-like, C-terminal domain
`XP_057769198.1`	Pfam	`PF03446`	NAD_binding_2	Domain	77	165	1.5e-05	25.8	NAD binding domain of 6-phosphogluconate dehydrogenase
`XP_057769198.1`	Pfam	`PF03807`	F420_oxidored	Family	77	166	4.5e-11	43.9	NADP oxidoreductase coenzyme F420-dependent
`XP_057769198.1`	Pfam	`PF02153`	PDH_N	Domain	90	200	2.3e-09	37.6	Prephenate dehydrogenase, nucleotide-binding domain
`XP_057769198.1`	Pfam	`PF26213`	TYRAAT1_C	Domain	263	336	6.1e-36	122.7	TYRAAT1-like, C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057913207.1
ACTATTTTCGTTGGAACCGCTCAAAAGGAATACGCACAGCTTTGGTTAAACAAATGGAGTAATTTTTTATTAAAATTTGCGTTGAATTCAACTACGCATAATTCAGACGTGAGAATGATGATGCCATTATCATTCATCCGTAAGTCTAAATTGAACGCTAATGGAAGTGACGAAACCAATCCAAGCCTAGCACCGCCTCTCCCTTTCTCCGCCCGCGCGCACCGCATTTCATTCGCACCGCATTCCTGCTTCAACTTTGC...

XM_057913215.1
ACTATTTTCGTTGGAACCGCTCAAAAGGAATACGCACAGCTTTGGTTAAACAAATGGAGTAATTTTTTATTAAAATTTGCGTTGAATTCAACTACGCATAATTCAGACGTGAGAATGATGATGCCATTATCATTCATCCGTAAGTCTAAATTGAACGCTAATGGAAGTGACGAAACCAATCCAAGCCTAGCACCGCCTCTCCCTTTCTCCGCCCGCGCGCACCGCATTTCATTCGCACCGCATTCCTGCTTCAACTTTGC...

CDS

2 records

下载 CDS FASTA

LOC130989248
ATGATTTCGTCCACATCAGTCCAGTCAACTCCCGCCGCGCAATCTGCAGCCGCCGGAGCCTCGCGGCTCCTCCACAGCAATGTCCACCACCTATCATTCTTCTTGCCGCTTCAGCACCACCACCGGCATTCCCGCCGCCAGAGCCTTCGCATCCGTGCAATCGACGCCGCGCAGCCCTACGACTTGGAGGCGCGCCTGGTCAAGCGCTTGAATCAGTCCACCAGACTCAAAATCGCCATTATTGGGTTCGGAAACTTCGG...

Protein

2 records

下载 Protein FASTA

XP_057769190.1
MISSTSVQSTPAAQSAAAGASRLLHSNVHHLSFFLPLQHHHRHSRRQSLRIRAIDAAQPYDLEARLVKRLNQSTRLKIAIIGFGNFGQFLAKALIRQGHTVYAHSRSNYRLIAESIGAGFVPDPHDLCEQHPDVMLICTSIISTESVLRSLPLQRLRRNTLFVDVLSVKEFPKNIFLQVLPPHFDILCTHPMFGPESGKHSWQNLPFVFDKVRIGAEDSRLARVENFLDIFRNEGCRMVEMSCEEHDRYAAGTQFITHTT...

XP_057769198.1
MISSTSVQSTPAAQSAAAGASRLLHSNVHHLSFFLPLQHHHRHSRRQSLRIRAIDAAQPYDLEARLVKRLNQSTRLKIAIIGFGNFGQFLAKALIRQGHTVYAHSRSNYRLIAESIGAGFVPDPHDLCEQHPDVMLICTSIISTESVLRSLPLQRLRRNTLFVDVLSVKEFPKNIFLQVLPPHFDILCTHPMFGPESGKHSWQNLPFVFDKVRIGAEDSRLARVENFLDIFRNEGCRMVEMSCEEHDRYAAGTQFITHTT...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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