Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr06G001577`

染色体: Chr06 坐标: 17223440-17225565 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr06G001577`
名称	SmilChr06G001577
描述	probable E3 ubiquitin-protein ligase RHC1A
染色体 / SeqID	Chr06 / NC_080392.1
坐标与链方向	17223440 - 17225565 / `-`

ID 对照

NCBI Gene ID	`LOC130990251`
GeneID	`130990251`
locus_tag	`-`
NCBI Name	`LOC130990251`
原始查询	`LOC130990251`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	probable E3 ubiquitin-protein ligase RHC1A
产物	probable E3 ubiquitin-protein ligase RHC1A
Arabidopsis	`AT2G40830` (RHC1A) RING-H2 finger C1A [Source:NCBI gene (formerly Entrezgene);Acc:818680] identity=35.8; qcov=1.25; evalue=1.23e-59; confidence=medium
Rice	`Os03g0351800` (OsRFP) - identity=40.2; qcov=1.04; evalue=1e-60; confidence=medium
GO	GO:0005654 (nucleoplasm); GO:0005737 (cytoplasm); GO:0061630 (ubiquitin protein ligase activity)
KEGG	-
Pfam	PF00097 (zf-C3HC4); PF12678 (zf-rbx1); PF12861 (zf-ANAPC11); PF13445 (zf-RING_UBOX); PF13639 (zf-RING_2); PF13923 (zf-C3HC4_2); PF14369 (Zn_ribbon_19); PF17123 (zf-RING_11)
InterPro	-
eggNOG	-
NR	GeneID:130990251

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057770462.1`
2	Cytosol	细胞质基质	0.80000	`XP_057770462.1`
3	Nucleus	细胞核	0.60000	`XP_057770462.1`
4	Chromosome	染色体	0.00000	`XP_057770462.1`
5	Centromere	着丝粒	0.00000	`XP_057770462.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr6:17223720`	`C`	`T`	EMS_canonical_SNV	stop_gained	2	B132,D3
`Chr6:17223720`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B132,D3
`Chr6:17223817`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B34,C85
`Chr6:17223819`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C14
`Chr6:17223935`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C74
`Chr6:17223937`	`AC`	`A`	1bp_deletion	frameshift_variant	1	C33
`Chr6:17223937`	`AC`	`A`	1bp_deletion	CDS_variant	1	C33
`Chr6:17223939`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C33
`Chr6:17224071`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C23
`Chr6:17224128`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B131,B140,B32
`Chr6:17224226`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C39
`Chr6:17224262`	`G`	`A`	EMS_canonical_SNV	stop_gained	10	A20,B115,B22,B23,B85,B91,B97,C24,C78,C85

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057770462.1

264 aa

132

264

Zn_ribbon_19

zf-ANAPC11

zf-rbx1

zf-RING_2

zf-RING_11

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_2

PF14369 Zn_ribbon_19 7-37 aa PF12861 zf-ANAPC11 158-208 aa PF12678 zf-rbx1 161-205 aa PF13639 zf-RING_2 163-205 aa PF17123 zf-RING_11 164-191 aa PF13445 zf-RING_UBOX 164-202 aa PF00097 zf-C3HC4 164-204 aa PF13923 zf-C3HC4_2 164-204 aa

XP_057770463.1

264 aa

132

264

Zn_ribbon_19

zf-ANAPC11

zf-rbx1

zf-RING_2

zf-RING_11

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_2

XP_057770464.1

264 aa

132

264

Zn_ribbon_19

zf-ANAPC11

zf-rbx1

zf-RING_2

zf-RING_11

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_2

XP_057770465.1

264 aa

132

264

Zn_ribbon_19

zf-ANAPC11

zf-rbx1

zf-RING_2

zf-RING_11

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_2

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057770462.1`	Pfam	`PF14369`	Zn_ribbon_19	Domain	7	37	1.6e-09	38.5	zinc-ribbon
`XP_057770462.1`	Pfam	`PF12861`	zf-ANAPC11	Domain	158	208	2.3e-06	28.2	Anaphase-promoting complex subunit 11 RING-H2 finger
`XP_057770462.1`	Pfam	`PF12678`	zf-rbx1	Domain	161	205	1.8e-07	32.0	RING-H2 zinc finger domain
`XP_057770462.1`	Pfam	`PF13639`	zf-RING_2	Domain	163	205	4.6e-13	49.9	Ring finger domain
`XP_057770462.1`	Pfam	`PF17123`	zf-RING_11	Domain	164	191	4.3e-08	33.4	RING-like zinc finger
`XP_057770462.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	164	202	1.4e-06	28.9	RING-type zinc-finger
`XP_057770462.1`	Pfam	`PF00097`	zf-C3HC4	Domain	164	204	2.9e-07	31.0	Zinc finger, C3HC4 type (RING finger)
`XP_057770462.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	164	204	2.5e-10	40.7	Zinc finger, C3HC4 type (RING finger)
`XP_057770463.1`	Pfam	`PF14369`	Zn_ribbon_19	Domain	7	37	1.6e-09	38.5	zinc-ribbon
`XP_057770463.1`	Pfam	`PF12861`	zf-ANAPC11	Domain	158	208	2.3e-06	28.2	Anaphase-promoting complex subunit 11 RING-H2 finger
`XP_057770463.1`	Pfam	`PF12678`	zf-rbx1	Domain	161	205	1.8e-07	32.0	RING-H2 zinc finger domain
`XP_057770463.1`	Pfam	`PF13639`	zf-RING_2	Domain	163	205	4.6e-13	49.9	Ring finger domain
`XP_057770463.1`	Pfam	`PF17123`	zf-RING_11	Domain	164	191	4.3e-08	33.4	RING-like zinc finger
`XP_057770463.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	164	202	1.4e-06	28.9	RING-type zinc-finger
`XP_057770463.1`	Pfam	`PF00097`	zf-C3HC4	Domain	164	204	2.9e-07	31.0	Zinc finger, C3HC4 type (RING finger)
`XP_057770463.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	164	204	2.5e-10	40.7	Zinc finger, C3HC4 type (RING finger)
`XP_057770464.1`	Pfam	`PF14369`	Zn_ribbon_19	Domain	7	37	1.6e-09	38.5	zinc-ribbon
`XP_057770464.1`	Pfam	`PF12861`	zf-ANAPC11	Domain	158	208	2.3e-06	28.2	Anaphase-promoting complex subunit 11 RING-H2 finger
`XP_057770464.1`	Pfam	`PF12678`	zf-rbx1	Domain	161	205	1.8e-07	32.0	RING-H2 zinc finger domain
`XP_057770464.1`	Pfam	`PF13639`	zf-RING_2	Domain	163	205	4.6e-13	49.9	Ring finger domain
`XP_057770464.1`	Pfam	`PF17123`	zf-RING_11	Domain	164	191	4.3e-08	33.4	RING-like zinc finger
`XP_057770464.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	164	202	1.4e-06	28.9	RING-type zinc-finger
`XP_057770464.1`	Pfam	`PF00097`	zf-C3HC4	Domain	164	204	2.9e-07	31.0	Zinc finger, C3HC4 type (RING finger)
`XP_057770464.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	164	204	2.5e-10	40.7	Zinc finger, C3HC4 type (RING finger)
`XP_057770465.1`	Pfam	`PF14369`	Zn_ribbon_19	Domain	7	37	1.6e-09	38.5	zinc-ribbon
`XP_057770465.1`	Pfam	`PF12861`	zf-ANAPC11	Domain	158	208	2.3e-06	28.2	Anaphase-promoting complex subunit 11 RING-H2 finger
`XP_057770465.1`	Pfam	`PF12678`	zf-rbx1	Domain	161	205	1.8e-07	32.0	RING-H2 zinc finger domain
`XP_057770465.1`	Pfam	`PF13639`	zf-RING_2	Domain	163	205	4.6e-13	49.9	Ring finger domain
`XP_057770465.1`	Pfam	`PF17123`	zf-RING_11	Domain	164	191	4.3e-08	33.4	RING-like zinc finger
`XP_057770465.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	164	202	1.4e-06	28.9	RING-type zinc-finger
`XP_057770465.1`	Pfam	`PF00097`	zf-C3HC4	Domain	164	204	2.9e-07	31.0	Zinc finger, C3HC4 type (RING finger)
`XP_057770465.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	164	204	2.5e-10	40.7	Zinc finger, C3HC4 type (RING finger)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057914480.1
GGATCATCAATCGGCCATTAGTGTTCGGCCCAAAGAGAACGGGCTTTAATGAGAGTACATCTTTCTTCCCCAAACATTGGCGGATTAGGACAGGCTGCACCCACTCTCTCTCTCTCTAAGTTTTAATAATGGCTTCCCCATTTTCAACTACTACTGTTAATTGCGTTGGTGTATGATTGCTGTCTTCTCTCTCCACAAGCTCACACACACTTTGTGTAGATTCGAATTTCCATAGGCATAATGCGGAGTTAACTTTACAT...

XM_057914482.1
AAAGAGAACGGGCTTTAATGAGAGTACATCTTTCTTCCCCAAACATTGGCGGATTAGGACAGGCTGCACCCACTCTCTCTCTCTCTAAGTTTTAATAATGGCTTCCCCATTTTCAACTACTACTGTTAATTGCGTTGGTAATTAGATATCTTTTGGTGGTGGATGTAGAGAGAAGGGATGCCGAGTGAAAGGGGCACTCATTGGTGCTATAGTTGTAGGGCAAGCGTCAGTCTCCGAGGGAGAGACGCAGAGTGCCCCGA...

CDS

4 records

下载 CDS FASTA

LOC130990251
ATGCCGAGTGAAAGGGGCACTCATTGGTGCTATAGTTGTAGGGCAAGCGTCAGTCTCCGAGGGAGAGACGCAGAGTGCCCCGACTGCAGAGGAAGTTTCATCCAAGAGCTCGAGGATGCAACGAGCATGGCAGACGAGGAACACATCCAAGAGCCGAGGTTCATGGAGGCAGCCACCAGTTTCCTCAGGCGGCACAGGGCTGTCGTATCCGATCAGAATGCCGATTCGTGGAACTCATTCCTCATTTTCAGCGGGGACAT...

Protein

4 records

下载 Protein FASTA

XP_057770462.1
MPSERGTHWCYSCRASVSLRGRDAECPDCRGSFIQELEDATSMADEEHIQEPRFMEAATSFLRRHRAVVSDQNADSWNSFLIFSGDMPARMPGSGGLVEFLNETLGFRRQNGGDYFIGPGVEEFFEHVTSDSRQRIPQPASRSSIDALPTVKISRRHVRADSTCAVCKERFELGSRVRKLPCKHLYHSDCIVPWLQQRSSCPVCRQQIINGGEQSRRDEQETRRRWSFSWPFGSSRSGSRRRERGGEASHHNHRAHYSSW...

XP_057770463.1
MPSERGTHWCYSCRASVSLRGRDAECPDCRGSFIQELEDATSMADEEHIQEPRFMEAATSFLRRHRAVVSDQNADSWNSFLIFSGDMPARMPGSGGLVEFLNETLGFRRQNGGDYFIGPGVEEFFEHVTSDSRQRIPQPASRSSIDALPTVKISRRHVRADSTCAVCKERFELGSRVRKLPCKHLYHSDCIVPWLQQRSSCPVCRQQIINGGEQSRRDEQETRRRWSFSWPFGSSRSGSRRRERGGEASHHNHRAHYSSW...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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