Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G000172`

染色体: Chr07 坐标: 1074737-1077687 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G000172`
名称	SmilChr07G000172
描述	uncharacterized SmilChr07G000172
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	1074737 - 1077687 / `-`

ID 对照

NCBI Gene ID	`LOC130991364`
GeneID	`130991364`
locus_tag	`-`
NCBI Name	`LOC130991364`
原始查询	`LOC130991364`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	nonsense-mediated mRNA decay NMD3 family protein [Source:NCBI gene (formerly Entrezgene);Acc:814908]; symbol=NMD3; hit=AT2G03820; species=arabidopsis; confidence=high
产物	nonsense-mediated mRNA decay NMD3 family protein [Source:NCBI gene (formerly Entrezgene);Acc:814908]; symbol=NMD3; hit=AT2G03820; species=arabidopsis; confidence=high
Arabidopsis	`AT2G03820` (NMD3) nonsense-mediated mRNA decay NMD3 family protein [Source:NCBI gene (formerly Entrezgene);Acc:814908] identity=59.6; qcov=1.04; evalue=0; confidence=high
Rice	`Os10g0573900` (OsNMD3) - identity=52.3; qcov=1.03; evalue=3.35e-167; confidence=high
GO	GO:0000055 (ribosomal large subunit export from nucleus); GO:0005634 (nucleus); GO:0005737 (cytoplasm); GO:0043023 (ribosomal large subunit binding)
KEGG	smil03008 (Ribosome biogenesis in eukaryotes - Salvia miltiorrhiza (redroot sage)); smil03013 (Nucleocytoplasmic transport - Salvia miltiorrhiza (redroot sage))
Pfam	PF04981 (NMD3); PF21192 (OB_NMD3); PF21193 (NMD_SH3); PF29994 (NMD3_N)
InterPro	-
eggNOG	-
NR	GeneID:130991364

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057771516.1`
2	Cytoplasm	细胞质	0.80000	`XP_057771516.1`
3	Nucleolus	核仁	0.60000	`XP_057771516.1`
4	Chromosome	染色体	0.00000	`XP_057771516.1`
5	Centromere	着丝粒	0.00000	`XP_057771516.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:1074884`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B23,B46
`Chr7:1074936`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B101,B46
`Chr7:1074945`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B14,B74,C83
`Chr7:1075074`	`CG`	`C`	1bp_deletion	frameshift_variant	1	B50
`Chr7:1075074`	`CG`	`C`	1bp_deletion	CDS_variant	1	B50
`Chr7:1075084`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C86
`Chr7:1075121`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C18
`Chr7:1075178`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C49
`Chr7:1075340`	`C`	`CTA`	2bp_insertion	frameshift_variant	122	A1,A13,A20,A22,A24,A25,A3,A4,A5,A6,A7,B1,B100,B105,B106,B108,B113,B114,B117,B118,B119,B12,B121,B122,B123,B125,B128,B129,B13,B135,B137,B140,B15,B16,B2,B25,B27,B28,B31,B33,B40,B43,B47,B48,B50,B52,B53,B55,B56,B58,B59,B60,B61,B62,B64,B65,B66,B67,B69,B73,B76,B78,B81,B83,B86,B87,B88,B9,B90,B92,B93,B95,B96,B99,C1,C10,C11,C14,C15,C16,C2,C20,C21,C22,C23,C24,C25,C26,C27,C28,C29,C3,C31,C34,C36,C4,C42,C44,C47,C48,C49,C56,C59,C61,C62,C63,C64,C68,C69,C7,C70,C71,C73,C76,C79,C84,C86,D10,D2,D3,D4,D8
`Chr7:1075342`	`ACG`	`A`	2bp_deletion	frameshift_variant	129	A1,A13,A18,A20,A22,A24,A25,A3,A4,A5,A6,A7,B1,B100,B105,B106,B108,B113,B114,B117,B118,B119,B12,B121,B122,B123,B125,B128,B129,B13,B135,B137,B140,B15,B16,B2,B21,B25,B27,B28,B31,B33,B34,B40,B43,B47,B48,B50,B51,B52,B53,B55,B56,B58,B59,B60,B61,B62,B64,B65,B66,B67,B69,B73,B76,B78,B81,B83,B86,B87,B88,B9,B90,B92,B93,B95,B96,B99,C1,C10,C11,C13,C14,C15,C16,C2,C20,C21,C22,C23,C24,C25,C26,C27,C28,C29,C3,C31,C34,C36,C4,C42,C44,C47,C48,C49,C56,C59,C61,C62,C63,C64,C65,C68,C69,C7,C70,C71,C73,C76,C79,C84,C86,C87,D10,D2,D3,D4,D8
`Chr7:1075582`	`GCA`	`G`	2bp_deletion	frameshift_variant	22	A11,A21,A22,A23,B1,B112,B120,B16,B23,B24,B28,B30,B48,B51,B57,B61,B99,C25,C55,C59,C87,D8
`Chr7:1075585`	`T`	`TGC`	2bp_insertion	frameshift_variant	22	A11,A21,A22,A23,B1,B112,B120,B16,B23,B24,B28,B30,B48,B51,B57,B61,B99,C25,C55,C59,C87,D8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057771516.1

479 aa

240

479

NMD3_N

NMD3

NMD_SH3

OB_NMD3

PF29994 NMD3_N 13-143 aa PF04981 NMD3 148-244 aa PF21193 NMD_SH3 247-292 aa PF21192 OB_NMD3 311-399 aa

XP_057771518.1

479 aa

240

479

NMD3_N

NMD3

NMD_SH3

OB_NMD3

PF29994 NMD3_N 13-143 aa PF04981 NMD3 148-244 aa PF21193 NMD_SH3 247-292 aa PF21192 OB_NMD3 311-399 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057771516.1`	Pfam	`PF29994`	NMD3_N	Domain	13	143	6.8e-35	121.2	NMD3, N-terminal domain
`XP_057771516.1`	Pfam	`PF04981`	NMD3	Domain	148	244	1.9e-27	96.4	NMD3, second domain
`XP_057771516.1`	Pfam	`PF21193`	NMD_SH3	Domain	247	292	1e-16	61.5	NMD3 SH3 domain
`XP_057771516.1`	Pfam	`PF21192`	OB_NMD3	Domain	311	399	8.6e-29	100.4	NMD3 OB-fold domain
`XP_057771518.1`	Pfam	`PF29994`	NMD3_N	Domain	13	143	6.8e-35	121.2	NMD3, N-terminal domain
`XP_057771518.1`	Pfam	`PF04981`	NMD3	Domain	148	244	1.9e-27	96.4	NMD3, second domain
`XP_057771518.1`	Pfam	`PF21193`	NMD_SH3	Domain	247	292	1e-16	61.5	NMD3 SH3 domain
`XP_057771518.1`	Pfam	`PF21192`	OB_NMD3	Domain	311	399	8.6e-29	100.4	NMD3 OB-fold domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057915533.1
ATACAAACAATAAACAAAGAATCCCTAATCTAAGTTAGAATCGGCGTCGCTCAGCTCTTCTTCTTCACGCCCTTTCTCAGAAAATCAGAAACGCCGATCTTCTTCCTCACAGATTTTTCGGCTTCTCTTCATCGGTATGTTTAGTGTGGCACAGACGATGGGCAGTGCGTTATGCTGCAAGTGCGGCATCGAAATGCCACCAAACGCTGCAAACATGTGTGCCAACTGCCTCCGCTCCGAAGTCGACATAACGGAGGGCC...

XM_057915535.1
TCTAAGTTAGAATCGGCGTCGCTCAGCTCTTCTTCTTCACGCCCTTTCTCAGAAAATCAGAAACGCCGATCTTCTTCCTCACAGATTTTTCGGCTTCTCTTCATCGCAGGTATGTTTAGTGTGGCACAGACGATGGGCAGTGCGTTATGCTGCAAGTGCGGCATCGAAATGCCACCAAACGCTGCAAACATGTGTGCCAACTGCCTCCGCTCCGAAGTCGACATAACGGAGGGCCTTCAGAGGCACACAAACATCCACCA...

CDS

2 records

下载 CDS FASTA

LOC130991364
ATGTTTAGTGTGGCACAGACGATGGGCAGTGCGTTATGCTGCAAGTGCGGCATCGAAATGCCACCAAACGCTGCAAACATGTGTGCCAACTGCCTCCGCTCCGAAGTCGACATAACGGAGGGCCTTCAGAGGCACACAAACATCCACCATTGCCCCCAATGCGAACGCTACCAGCAGCCTCCCGGCACTTGGATCAAAGCAGAGCTCGAGTCGAATGAGCTTCTCGCGCTCTGCTTGAAGAGCCTCAAGAAACTCAACAC...

Protein

2 records

下载 Protein FASTA

XP_057771516.1
MFSVAQTMGSALCCKCGIEMPPNAANMCANCLRSEVDITEGLQRHTNIHHCPQCERYQQPPGTWIKAELESNELLALCLKSLKKLNTVRVVDVGFIWTEPHSKRIRIKLRVQKEVLVGAVLEQAYTVEYTVQDHLCELCVRARANPDQWEAVVQLRQHVPHRRTFFYLEQLILKHDAAKDAVRIKQMEQGIDFFFRKENHAVKFVDFVGKVAPIDEVKRENHRLVSHDTKSNRSNSKYAFSVVISPVCREDLICLPPEVS...

XP_057771518.1
MFSVAQTMGSALCCKCGIEMPPNAANMCANCLRSEVDITEGLQRHTNIHHCPQCERYQQPPGTWIKAELESNELLALCLKSLKKLNTVRVVDVGFIWTEPHSKRIRIKLRVQKEVLVGAVLEQAYTVEYTVQDHLCELCVRARANPDQWEAVVQLRQHVPHRRTFFYLEQLILKHDAAKDAVRIKQMEQGIDFFFRKENHAVKFVDFVGKVAPIDEVKRENHRLVSHDTKSNRSNSKYAFSVVISPVCREDLICLPPEVS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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