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中文 EN

Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。
示例

当前解析结果

SmilChr07G000190

染色体: Chr07 坐标: 1200451-1204401 链方向: + 类型: protein_coding

基本信息

统一新 Gene IDSmilChr07G000190
名称SmilChr07G000190
描述serine hydroxymethyltransferase 3, chloroplastic
染色体 / SeqIDChr07 / NC_080393.1
坐标与链方向1200451 - 1204401 / +

ID 对照

NCBI Gene IDLOC130991382
GeneID130991382
locus_tag-
NCBI NameLOC130991382
原始查询LOC130991382

查看完整 ID 对照表

功能注释

来源GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述serine hydroxymethyltransferase 3, chloroplastic
产物serine hydroxymethyltransferase 3%2C chloroplastic
ArabidopsisAT4G32520 (SHM3)
serine hydroxymethyltransferase 3 [Source:NCBI gene (formerly Entrezgene);Acc:829387]
identity=79.6; qcov=1; evalue=0; confidence=high
RiceOs03g0738400 (OsSHM1)
-
identity=62.3; qcov=0.877; evalue=0; confidence=high
GOGO:0004372 (glycine hydroxymethyltransferase activity); GO:0005737 (cytoplasm); GO:0006565 (L-serine catabolic process); GO:0008270 (zinc ion binding); GO:0019264 (GO:0019264); GO:0030170 (pyridoxal phosphate binding); GO:0035999 (tetrahydrofolate interconversion); GO:0046655 (folic acid metabolic process); GO:0050897 (cobalt ion binding); GO:0070905 (serine binding)
KEGGsmil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00460 (Cyanoamino acid metabolism - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil00670 (One carbon pool by folate - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage)); smil04981 (Folate transport and metabolism - Salvia miltiorrhiza (redroot sage))
PfamPF00464 (SHMT)
InterPro-
eggNOG-
NRGeneID:130991382

打开注释模块

亚细胞定位 Top 5

Rank定位位置中文ScoreProtein ID
1 Chloroplast 叶绿体 1.00000 XP_057771544.1
2 Chloroplast stroma 叶绿体基质 1.00000 XP_057771544.1
3 Mitochondrion 线粒体 0.40000 XP_057771549.1
4 Nucleus 细胞核 0.00000 XP_057771544.1
5 Chromosome 染色体 0.00000 XP_057771544.1

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置 REF ALT 类型 影响 携带材料数 材料
Chr7:1201243 G GC 1bp_insertion frameshift_variant 7 B3,B4,B54,C12,C15,C21,C42
Chr7:1201254 C T EMS_canonical_SNV CDS_variant 2 C41,C45
Chr7:1201557 G A EMS_canonical_SNV CDS_variant 3 B3,C15,C21
Chr7:1201727 C T EMS_canonical_SNV CDS_variant 4 B135,B25,B34,C13
Chr7:1201892 C T EMS_canonical_SNV CDS_variant 1 B88
Chr7:1201997 C T EMS_canonical_SNV CDS_variant 2 C41,C45
Chr7:1202120 C T EMS_canonical_SNV CDS_variant 1 C74
Chr7:1202132 G A EMS_canonical_SNV CDS_variant 1 B99
Chr7:1202561 G A EMS_canonical_SNV CDS_variant 2 B65,C60
Chr7:1203608 C T EMS_canonical_SNV CDS_variant 5 B30,B69,B99,C19,C56
Chr7:1203614 G A EMS_canonical_SNV CDS_variant 1 B18
Chr7:1204068 G A EMS_canonical_SNV CDS_variant 1 C2

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057771544.1
530 aa
N
1
265
530
SHMT
C
PF00464 SHMT 84-474 aa
XP_057771545.1
530 aa
N
1
265
530
SHMT
C
PF00464 SHMT 84-474 aa
XP_057771546.1
530 aa
N
1
265
530
SHMT
C
PF00464 SHMT 84-474 aa
XP_057771547.1
530 aa
N
1
265
530
SHMT
C
PF00464 SHMT 84-474 aa
XP_057771548.1
523 aa
N
1
262
523
SHMT
C
PF00464 SHMT 77-467 aa
XP_057771549.1
520 aa
N
1
260
520
SHMT
C
PF00464 SHMT 74-464 aa
Protein ID 来源 结构域编号 结构域名称 类型 起始 aa 终止 aa E-value Score 说明
XP_057771544.1 Pfam PF00464 SHMT Domain 84 474 2.5e-192 639.6 Serine hydroxymethyltransferase
XP_057771545.1 Pfam PF00464 SHMT Domain 84 474 2.5e-192 639.6 Serine hydroxymethyltransferase
XP_057771546.1 Pfam PF00464 SHMT Domain 84 474 2.5e-192 639.6 Serine hydroxymethyltransferase
XP_057771547.1 Pfam PF00464 SHMT Domain 84 474 2.5e-192 639.6 Serine hydroxymethyltransferase
XP_057771548.1 Pfam PF00464 SHMT Domain 77 467 2.4e-192 639.6 Serine hydroxymethyltransferase
XP_057771549.1 Pfam PF00464 SHMT Domain 74 464 2.3e-192 639.7 Serine hydroxymethyltransferase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

6 records

下载 cDNA FASTA
XM_057915563.1
GGCCTCGGCCCATCTGCCAGCGACTCTATAGAAGCCCATGACTTCTCTCCAGCCCAACAACTACTGTGAATGTGGAGTGAAGAAGTTGAGCAGCAGCGTAAATATATCTATCGGAAAAGGAGAAGAAATAAGCGGCGCGCGCTTTTTCTGGGCAGCTAGGTTTTCTCATTTCCCAATTATTCTCGATTAGAGGAAAATCGACGCAAAATCATCAGGCTTCGCGATATTGCTGCGTGTATAATTCAGAAAATTATTACTAC...
XM_057915565.1
GGCCTCGGCCCATCTGCCAGCGACTCTATAGAAGCCCATGACTTCTCTCCAGCCCAACAACTACTGTGAATGTGGAGTGAAGAAGTTGAGCAGCAGCGTAAATATATCTATCGGAAAAGGAGAAGAAATAAGCGGCGCGCGCTTTTTCTGGGCAGCTAGGTTTTCTCATTTCCCAATTATTCTCGATTAGAGGAAAATCGACGCAAAATCATCAGGCTTCGCGATATTGCTGCGTGTATAATTCAGAAAATTATTACTAC...

CDS

6 records

下载 CDS FASTA
LOC130991382
ATGCAGGTTTGTGGTGGATCTGCTGCAATCATGAATTCCATTCAACAACCTGTTGGGACCAAGACATCAGTATTTCCTTCAAACTGGATGGGCACCATTGGAAGCCCGAGTCATGTTAAAATGAGTTCGTTCAAGCCTTGCAGATCATCTCAACTTGAAGGGAGCTTAGTCACTGGGAGGCCGCCCTCTTCTGCGTCTGTTCCTGTACCTGAAATTGGAGGAGCTGGGAGCACCTTTGCAGACTATGGCTTGAAAGAAGT...
LOC130991382
ATGCAGGTTTGTGGTGGATCTGCTGCAATCATGAATTCCATTCAACAACCTGTTGGGACCAAGACATCAGTATTTCCTTCAAACTGGATGGGCACCATTGGAAGCCCGAGTCATGTTAAAATGAGTTCGTTCAAGCCTTGCAGATCATCTCAACTTGAAGGGAGCTTAGTCACTGGGAGGCCGCCCTCTTCTGCGTCTGTTCCTGTACCTGAAATTGGAGGAGCTGGGAGCACCTTTGCAGACTATGGCTTGAAAGAAGT...

Protein

6 records

下载 Protein FASTA
XP_057771544.1
MQVCGGSAAIMNSIQQPVGTKTSVFPSNWMGTIGSPSHVKMSSFKPCRSSQLEGSLVTGRPPSSASVPVPEIGGAGSTFADYGLKEVDPEIRSIIDKEKNRQFRSLELIASENFTSRAVMEAVGSCLTNKYSEGLPGKRYYGGNEFIDELETLCQERALAAFNLDGNKWGVNVQPLSGSPANFEVYTAVLNPHDRIMGLDLPHGGHLSHGFMTAKRRVSGTSIYFESMPYRLDETTGLVDYDMLEKTAALFRPKLIIAGA...
XP_057771545.1
MQVCGGSAAIMNSIQQPVGTKTSVFPSNWMGTIGSPSHVKMSSFKPCRSSQLEGSLVTGRPPSSASVPVPEIGGAGSTFADYGLKEVDPEIRSIIDKEKNRQFRSLELIASENFTSRAVMEAVGSCLTNKYSEGLPGKRYYGGNEFIDELETLCQERALAAFNLDGNKWGVNVQPLSGSPANFEVYTAVLNPHDRIMGLDLPHGGHLSHGFMTAKRRVSGTSIYFESMPYRLDETTGLVDYDMLEKTAALFRPKLIIAGA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

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