Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G000499`

染色体: Chr07 坐标: 3486831-3493243 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G000499`
名称	SmilChr07G000499
描述	cullin-1
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	3486831 - 3493243 / `-`

ID 对照

NCBI Gene ID	`LOC130991690`
GeneID	`130991690`
locus_tag	`-`
NCBI Name	`LOC130991690`
原始查询	`LOC130991690`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	cullin-1
产物	cullin-1
Arabidopsis	`AT4G02570` (CUL1) cullin 1 [Source:NCBI gene (formerly Entrezgene);Acc:825648] identity=83.1; qcov=0.995; evalue=0; confidence=high
Rice	`Os01g0369000` (OsCUL1-1) - identity=87.2; qcov=1; evalue=0; confidence=high
GO	GO:0006511 (ubiquitin-dependent protein catabolic process); GO:0016567 (protein ubiquitination); GO:0031461 (cullin-RING ubiquitin ligase complex); GO:0031625 (ubiquitin protein ligase binding)
KEGG	smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage)); smil04141 (Protein processing in endoplasmic reticulum - Salvia miltiorrhiza (redroot sage))
Pfam	PF00888 (Cullin); PF10557 (Cullin_Nedd8); PF26557 (Cullin_AB)
InterPro	-
eggNOG	-
NR	GeneID:130991690

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057772026.1`
2	Cytosol	细胞质基质	0.60000	`XP_057772026.1`
3	Cytoskeleton	细胞骨架	0.40000	`XP_057772026.1`
4	Phragmoplast	Phragmoplast	0.20000	`XP_057772026.1`
5	Midbody	Midbody	0.20000	`XP_057772026.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:3487828`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B138,B33
`Chr7:3487897`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B81
`Chr7:3487912`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A7,B110,D3
`Chr7:3488154`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B110,D3
`Chr7:3488683`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B78
`Chr7:3490555`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B129,C41,C9,D1
`Chr7:3491289`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B81
`Chr7:3491376`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B134
`Chr7:3491692`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B119,C21,C28
`Chr7:3491881`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A16,B140,B62,C86
`Chr7:3491980`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B101,B36,C10,C14

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057772026.1

744 aa

372

744

Cullin

Cullin_AB

Cullin_Nedd8

PF00888 Cullin 25-489 aa PF26557 Cullin_AB 514-647 aa PF10557 Cullin_Nedd8 674-736 aa

XP_057772027.1

744 aa

372

744

Cullin

Cullin_AB

Cullin_Nedd8

PF00888 Cullin 25-489 aa PF26557 Cullin_AB 514-647 aa PF10557 Cullin_Nedd8 674-736 aa

XP_057772028.1

744 aa

372

744

Cullin

Cullin_AB

Cullin_Nedd8

PF00888 Cullin 25-489 aa PF26557 Cullin_AB 514-647 aa PF10557 Cullin_Nedd8 674-736 aa

XP_057772029.1

744 aa

372

744

Cullin

Cullin_AB

Cullin_Nedd8

PF00888 Cullin 25-489 aa PF26557 Cullin_AB 514-647 aa PF10557 Cullin_Nedd8 674-736 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057772026.1`	Pfam	`PF00888`	Cullin	Repeat	25	489	4.3e-135	452.3	Cullin alpha solenoid domain
`XP_057772026.1`	Pfam	`PF26557`	Cullin_AB	Domain	514	647	3e-45	154.4	Cullin alpha+beta domain
`XP_057772026.1`	Pfam	`PF10557`	Cullin_Nedd8	Domain	674	736	5e-27	94.5	Cullin protein neddylation domain
`XP_057772027.1`	Pfam	`PF00888`	Cullin	Repeat	25	489	4.3e-135	452.3	Cullin alpha solenoid domain
`XP_057772027.1`	Pfam	`PF26557`	Cullin_AB	Domain	514	647	3e-45	154.4	Cullin alpha+beta domain
`XP_057772027.1`	Pfam	`PF10557`	Cullin_Nedd8	Domain	674	736	5e-27	94.5	Cullin protein neddylation domain
`XP_057772028.1`	Pfam	`PF00888`	Cullin	Repeat	25	489	4.3e-135	452.3	Cullin alpha solenoid domain
`XP_057772028.1`	Pfam	`PF26557`	Cullin_AB	Domain	514	647	3e-45	154.4	Cullin alpha+beta domain
`XP_057772028.1`	Pfam	`PF10557`	Cullin_Nedd8	Domain	674	736	5e-27	94.5	Cullin protein neddylation domain
`XP_057772029.1`	Pfam	`PF00888`	Cullin	Repeat	25	489	4.3e-135	452.3	Cullin alpha solenoid domain
`XP_057772029.1`	Pfam	`PF26557`	Cullin_AB	Domain	514	647	3e-45	154.4	Cullin alpha+beta domain
`XP_057772029.1`	Pfam	`PF10557`	Cullin_Nedd8	Domain	674	736	5e-27	94.5	Cullin protein neddylation domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057916043.1
AAATTCCAAATCCCAACAGGTACCTGGTGGTAGCACATAAAATTTCGAAAAGTTGAGGGGTCAAAAATGAAAAACGGAAACCTCAGTATACGATTTGAAAAATACTATAATAAACAAAATCAAGAAAAATGAAGATATGAAAAATAAGAAAACGGAAGGGGAAAACTAAAAAGATCGAGAGCGATTCACATCCTACCAAAGTCTCTCTCCCTTCAGGTTTTGAATCGTTTTAAGTGGTGATAAGTATTCATCTTGTCTAG...

XM_057916044.1
CTCTCTCTATATATATTTGCATATATATACACGATTATATATACTGTATGCGTCGACAGGCCGTGGATTTTTTTTTTTATATGTCGGTGTGGTAAAATTGTGTGTGCGGGTTTTGAATCGTTTTAAGTGGTGATAAGTATTCATCTTGTCTAGCACAGAAGATGACTATGAACCAGCGTAACACGATTGATTTGGAACAAGGATGGGATTTTATGCAAAAAGGGATCACAAAATTGAAAAATATTCTTGAAGGGCTGCCT...

CDS

4 records

下载 CDS FASTA

LOC130991690
ATGACTATGAACCAGCGTAACACGATTGATTTGGAACAAGGATGGGATTTTATGCAAAAAGGGATCACAAAATTGAAAAATATTCTTGAAGGGCTGCCTGAGCCCCAGTTCAGCTCAGAGGACTACATGATGCTCTACACGACAATCTACAACATGTGCACTCAAAAGCCCCCACATGATTATTCTCAACAATTATATGACAAGTACCGGGAGTCTTTCGAAGTGTACATTACAACGACGGTTCTGCCTTCTTTGAGGGA...

Protein

4 records

下载 Protein FASTA

XP_057772026.1
MTMNQRNTIDLEQGWDFMQKGITKLKNILEGLPEPQFSSEDYMMLYTTIYNMCTQKPPHDYSQQLYDKYRESFEVYITTTVLPSLREKHDEFMLRELVKRWLNHKIMVRWLSRFFHYLDRYFVARRSLPALKEVGLTCFRDLVYLELSGKVRDAVISLIDQEREGEQIDRALLKNVLDIFVEIGMGQMDYYENDFEAAMLKDTAAYYSRKASNWILDDSCPDYMLKAEECLKREKDRVAHYLHSSSESKLLEKVQHELLS...

XP_057772027.1
MTMNQRNTIDLEQGWDFMQKGITKLKNILEGLPEPQFSSEDYMMLYTTIYNMCTQKPPHDYSQQLYDKYRESFEVYITTTVLPSLREKHDEFMLRELVKRWLNHKIMVRWLSRFFHYLDRYFVARRSLPALKEVGLTCFRDLVYLELSGKVRDAVISLIDQEREGEQIDRALLKNVLDIFVEIGMGQMDYYENDFEAAMLKDTAAYYSRKASNWILDDSCPDYMLKAEECLKREKDRVAHYLHSSSESKLLEKVQHELLS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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