Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G003378`

染色体: Chr01 坐标: 52457879-52462451 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G003378`
名称	SmilChr01G003378
描述	carbamoyl-phosphate synthase large chain, chloroplastic
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	52457879 - 52462451 / `-`

ID 对照

NCBI Gene ID	`LOC130992086`
GeneID	`130992086`
locus_tag	`-`
NCBI Name	`LOC130992086`
原始查询	`LOC130992086`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	carbamoyl-phosphate synthase large chain, chloroplastic
产物	carbamoyl-phosphate synthase large chain%2C chloroplastic
Arabidopsis	`AT1G29900` (CARB) carbamoyl phosphate synthetase B [Source:NCBI gene (formerly Entrezgene);Acc:839868] identity=86.7; qcov=0.917; evalue=0; confidence=high
Rice	`Os01g0570700` - identity=74.2; qcov=0.276; evalue=5.01e-168; confidence=weak
GO	GO:0005524 (ATP binding); GO:0005737 (cytoplasm); GO:0006541 (L-glutamine metabolic process); GO:0046872 (metal ion binding)
KEGG	smil00220 (Arginine biosynthesis - Salvia miltiorrhiza (redroot sage)); smil00240 (Pyrimidine metabolism - Salvia miltiorrhiza (redroot sage)); smil00250 (Alanine, aspartate and glutamate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage))
Pfam	PF02142 (MGS); PF02222 (ATP-grasp); PF02786 (CPSase_L_D2); PF02787 (CPSase_L_D3); PF07478 (Dala_Dala_lig_C); PF25596 (CPSase_L_D1)
InterPro	-
eggNOG	-
NR	GeneID:130992086

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057772545.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057772545.1`
3	Nucleus	细胞核	0.00000	`XP_057772545.1`
4	Chromosome	染色体	0.00000	`XP_057772545.1`
5	Centromere	着丝粒	0.00000	`XP_057772545.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:52458076`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B1,B10,B94,C74
`Chr1:52458078`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C25,D3
`Chr1:52458102`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A14,B28,B59,C38,C75
`Chr1:52458120`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B11,C10,C4,C54
`Chr1:52458197`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B10,B94
`Chr1:52458240`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A18,B107,B3,C29,C86
`Chr1:52458353`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B4,C36
`Chr1:52458375`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B20
`Chr1:52458442`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C39
`Chr1:52458444`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A14,B28,B59,C38,D10
`Chr1:52458503`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C32
`Chr1:52458552`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B77

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057772545.1

1190 aa

595

1190

CPSase_L_D1

CPSase_L_D2

CPSase_L_D3

CPSase_L_D1

CPSase_L_D2

ATP-grasp

Dala_Dala_lig_C

MGS

PF25596 CPSase_L_D1 91-208 aa PF02786 CPSase_L_D2 212-419 aa PF02787 CPSase_L_D3 467-603 aa PF25596 CPSase_L_D1 642-766 aa PF02786 CPSase_L_D2 770-973 aa PF02222 ATP-grasp 778-944 aa PF07478 Dala_Dala_lig_C 795-942 aa PF02142 MGS 1057-1141 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057772545.1`	Pfam	`PF25596`	CPSase_L_D1	Domain	91	208	2.5e-97	321.6	Carbamoyl phosphate synthase preATP-grasp domain
`XP_057772545.1`	Pfam	`PF02786`	CPSase_L_D2	Domain	212	419	2.9e-112	374.0	Carbamoyl-phosphate synthase L chain, ATP binding domain
`XP_057772545.1`	Pfam	`PF02787`	CPSase_L_D3	Domain	467	603	1.8e-42	145.3	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
`XP_057772545.1`	Pfam	`PF25596`	CPSase_L_D1	Domain	642	766	2.5e-97	321.6	Carbamoyl phosphate synthase preATP-grasp domain
`XP_057772545.1`	Pfam	`PF02786`	CPSase_L_D2	Domain	770	973	2.9e-112	374.0	Carbamoyl-phosphate synthase L chain, ATP binding domain
`XP_057772545.1`	Pfam	`PF02222`	ATP-grasp	Domain	778	944	2.2e-10	41.2	ATP-grasp domain
`XP_057772545.1`	Pfam	`PF07478`	Dala_Dala_lig_C	Family	795	942	2.3e-14	54.1	D-ala D-ala ligase C-terminus
`XP_057772545.1`	Pfam	`PF02142`	MGS	Domain	1057	1141	3.4e-22	79.1	MGS-like domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057916562.1
TAATTAATTATTACTACCATGAAGAGAGTGCCGTTAACACAATCTCTGAAACCCTAGTATCACTATAAATACAAATACAGCTCTCTCTGTCTGCACCATCGCACGCTCTCGCAGTGACAACGTAACGCCAATCATTCACCTCTCTCCGCCGCCATCAGCCAGGGGTTTGCTAATTTATTTGAAAGAAGAGAAAGGCGGGGTTTGAGAGGAGATGAGTCAGTCCCTGCATAGCTGCAATAATGTATTCTGTAAGTTTATTC...

CDS

1 records

下载 CDS FASTA

LOC130992086
ATGAGTCAGTCCCTGCATAGCTGCAATAATGTATTCTGTAAGTTTATTCAAACCAATCGTTACTTGCCTGCCGGAAAAAGGCCTCTTCCGCGCATTTCGCGGCAATCGAGGCTAGCATCGGACAAGAATTCGAGTAATTTATACTTGTCGACTCGCAATTTGGTGTTGAATTGTGTGAAATCTGAAAATGAGAGTGGTGGTGGTAGGAGTAGTGGTGATTTAGGGAATGGAGGGGGGTTTAGTGCTGAAAATATTGGTAA...

Protein

1 records

下载 Protein FASTA

XP_057772545.1
MSQSLHSCNNVFCKFIQTNRYLPAGKRPLPRISRQSRLASDKNSSNLYLSTRNLVLNCVKSENESGGGRSSGDLGNGGGFSAENIGKRTDIKKILILGAGPIVIGQACEFDYSGTQACKALKEEGYEVILINSNPATIMTDPEMADRTYIEPMTPELVEQVLEKERPDALLPTMGGQTALNLAVALAESGALEKYGVELIGAKLDAIKKAEDRELFKQAMKNIGLKTPPSGIGTTLEECFEIANWIGEFPLIIRPAFTLG...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

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