Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G001089`

染色体: Chr07 坐标: 8016930-8022919 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G001089`
名称	SmilChr07G001089
描述	formamidopyrimidine-DNA glycosylase
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	8016930 - 8022919 / `+`

ID 对照

NCBI Gene ID	`LOC130992263`
GeneID	`130992263`
locus_tag	`-`
NCBI Name	`LOC130992263`
原始查询	`LOC130992263`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	formamidopyrimidine-DNA glycosylase
产物	formamidopyrimidine-DNA glycosylase
Arabidopsis	`AT1G52500` (MMH-1) MUTM homolog-1 [Source:NCBI gene (formerly Entrezgene);Acc:841681] identity=61.9; qcov=0.85; evalue=9.25e-154; confidence=high
Rice	`Os06g0643600` (MutM) - identity=63.2; qcov=0.724; evalue=3.4e-143; confidence=high
GO	GO:0003684 (damaged DNA binding); GO:0003906 (DNA-(apurinic or apyrimidinic site) endonuclease activity); GO:0005634 (nucleus); GO:0006284 (base-excision repair); GO:0008270 (zinc ion binding); GO:0008534 (oxidized purine nucleobase lesion DNA N-glycosylase activity)
KEGG	smil03410 (Base excision repair - Salvia miltiorrhiza (redroot sage))
Pfam	PF01149 (Fapy_DNA_glyco); PF06831 (H2TH); PF21218 (Fpg-like_C)
InterPro	-
eggNOG	-
NR	GeneID:130992263

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057772799.1`
2	Nucleolus	核仁	0.60000	`XP_057772799.1`
3	Nucleoplasm	核质	0.20000	`XP_057772799.1`
4	Chromosome	染色体	0.00000	`XP_057772801.1`
5	Centromere	着丝粒	0.00000	`XP_057772801.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:8017252`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B131
`Chr7:8021112`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B118
`Chr7:8021138`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C49
`Chr7:8021241`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A11
`Chr7:8022098`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr7:8022468`	`AT`	`A`	1bp_deletion	frameshift_variant	5	B6,B69,B82,C67,D11
`Chr7:8022468`	`AT`	`A`	1bp_deletion	CDS_variant	5	B6,B69,B82,C67,D11
`Chr7:8022470`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B1

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057772799.1

408 aa

204

408

Fapy_DNA_glyco

H2TH

Fpg-like_C

PF01149 Fapy_DNA_glyco 1-131 aa PF06831 H2TH 146-236 aa PF21218 Fpg-like_C 240-273 aa

XP_057772800.1

407 aa

204

407

Fapy_DNA_glyco

H2TH

Fpg-like_C

PF01149 Fapy_DNA_glyco 1-131 aa PF06831 H2TH 146-236 aa PF21218 Fpg-like_C 240-272 aa

XP_057772801.1

439 aa

220

439

Fapy_DNA_glyco

H2TH

Fpg-like_C

PF01149 Fapy_DNA_glyco 1-131 aa PF06831 H2TH 146-236 aa PF21218 Fpg-like_C 271-304 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057772799.1`	Pfam	`PF01149`	Fapy_DNA_glyco	Domain	1	131	9.8e-30	104.3	Formamidopyrimidine-DNA glycosylase N-terminal domain
`XP_057772799.1`	Pfam	`PF06831`	H2TH	Domain	146	236	4.8e-28	97.7	Formamidopyrimidine-DNA glycosylase H2TH domain
`XP_057772799.1`	Pfam	`PF21218`	Fpg-like_C	Domain	240	273	1.6e-22	79.5	Formamidopyrimidine-DNA glycosylase-like, C-terminal domain
`XP_057772800.1`	Pfam	`PF01149`	Fapy_DNA_glyco	Domain	1	131	9.2e-30	104.4	Formamidopyrimidine-DNA glycosylase N-terminal domain
`XP_057772800.1`	Pfam	`PF06831`	H2TH	Domain	146	236	5.5e-26	91.1	Formamidopyrimidine-DNA glycosylase H2TH domain
`XP_057772800.1`	Pfam	`PF21218`	Fpg-like_C	Domain	240	272	5.1e-13	49.1	Formamidopyrimidine-DNA glycosylase-like, C-terminal domain
`XP_057772801.1`	Pfam	`PF01149`	Fapy_DNA_glyco	Domain	1	131	1.1e-29	104.1	Formamidopyrimidine-DNA glycosylase N-terminal domain
`XP_057772801.1`	Pfam	`PF06831`	H2TH	Domain	146	236	2.9e-26	92.0	Formamidopyrimidine-DNA glycosylase H2TH domain
`XP_057772801.1`	Pfam	`PF21218`	Fpg-like_C	Domain	271	304	1.1e-22	80.0	Formamidopyrimidine-DNA glycosylase-like, C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057916816.1
GTTTCTTCAAAGAAAAACTAGAACGCAAAATCAATAGCTTAATACTCCTATGGGCTATGGCAATGGCATGCAAATTTTCACCCATTTGAAGCGGGCTCTAATCTGGACTTTTTTACGGCCCGGGCTGGCCCAGGCCCACAACCAATAGCTTATTCTACGCCATACAAATTTACAGTACTACCCTCCCCGTCACAGGCGAAAGTGCGCGCCAACTTCTCTCACTCTTCTTTCTCGGCGTTGGAGCAGAGAAGTTCTACTGT...

XM_057916817.1
ACAGTACTACCCTCCCCGTCACAGGCGAAAGTGCGCGCCAACTTCTCTCACTCTTCTTTCTCGGCGTTGGAGCAGAGAAGTTCTACTGTCACCCTACAATGCCGGAGCTACCGGAGGTTGAGGCGGCGCGTCGGGCGCTGGCAGAGCACACCGTCGGGAAGAAGATAATAAAAGTGATTGTAGCTGATGATTCCAAAGTCATTGACGGTGTCTCTCCCAAGGACTTCGAGGCAGCGCTCGTTGGAAAAACTATCGTCGCC...

CDS

3 records

下载 CDS FASTA

LOC130992263
ATGCCGGAGCTACCGGAGGTTGAGGCGGCGCGTCGGGCGCTGGCAGAGCACACCGTCGGGAAGAAGATAATAAAAGTGATTGTAGCTGATGATTCCAAAGTCATTGACGGTGTCTCTCCCAAGGACTTCGAGGCAGCGCTCGTTGGAAAAACTATCGTCGCCACGCATCGGAAGGGAAAGAACATGTGGATTGAACTTGATTCCCCTCCTTTCCCCTCTTTTCAATTCGGAATGGCTGGGGCTGTATATATCAAGGGAGT...

Protein

3 records

下载 Protein FASTA

XP_057772799.1
MPELPEVEAARRALAEHTVGKKIIKVIVADDSKVIDGVSPKDFEAALVGKTIVATHRKGKNMWIELDSPPFPSFQFGMAGAVYIKGVAVTKYKRSVVKDTDEWPSKYSKLFVELADGLEFSFTDKRRFAKVRLLDNPVSVPPISELGPDALTEPMTEDELCNSLKKKNIGIKALLLDQSFLSGIGNWMADEVLYQARIHPLQTASSLSKECCTNLLKCINEVIEKALEVGADSSQFPDNWIFNSREKKPGKAFVDGKKLD...

XP_057772800.1
MPELPEVEAARRALAEHTVGKKIIKVIVADDSKVIDGVSPKDFEAALVGKTIVATHRKGKNMWIELDSPPFPSFQFGMAGAVYIKGVAVTKYKRSVVKDTDEWPSKYSKLFVELADGLEFSFTDKRRFAKVRLLDNPVSVPPISELGPDALTEPMTEDELCNSLKKKNIGIKALLLDQSFLSGIGNWMADEVLYQARIHPLQTASSLSKECCTNLLKCINEVTDFAVKVDADSLRFPTEWLFHFRWGKKPGKVNGKKLDF...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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