Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G001226`

染色体: Chr07 坐标: 9391494-9402439 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G001226`
名称	SmilChr07G001226
描述	regulator of telomere elongation helicase 1 homolog
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	9391494 - 9402439 / `-`

ID 对照

NCBI Gene ID	`LOC130992404`
GeneID	`130992404`
locus_tag	`-`
NCBI Name	`LOC130992404`
原始查询	`LOC130992404`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	regulator of telomere elongation helicase 1 homolog
产物	regulator of telomere elongation helicase 1 homolog
Arabidopsis	`AT1G79950` (AT1G79950) RAD3-like DNA-binding helicase protein [Source:NCBI gene (formerly Entrezgene);Acc:844335] identity=49.6; qcov=0.955; evalue=0; confidence=high
Rice	`Os01g0592900` - identity=50.8; qcov=0.965; evalue=0; confidence=high
GO	GO:0003677 (DNA binding); GO:0003678 (DNA helicase activity); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0010569 (regulation of double-strand break repair via homologous recombination); GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides); GO:0032508 (GO:0032508); GO:0045910 (negative regulation of DNA recombination); GO:0070182 (DNA polymerase binding); GO:0090657 (telomeric loop disassembly); GO:1904430 (negative regulation of t-circle formation)
KEGG	-
Pfam	PF06733 (DEAD_2); PF13307 (Helicase_C_2); PF23109 (ARCH_RTEL1); PF23116 (HHD_RTEL1)
InterPro	-
eggNOG	-
NR	GeneID:130992404

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057773005.1`
2	Cytoplasm	细胞质	0.40000	`XP_057773006.1`
3	Cytosol	细胞质基质	0.40000	`XP_057773006.1`
4	Chromosome	染色体	0.00000	`XP_057773005.1`
5	Centromere	着丝粒	0.00000	`XP_057773005.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:9391817`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B72,B90,B92,C21,C25
`Chr7:9391841`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C46
`Chr7:9392297`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A16,C60
`Chr7:9394354`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B44
`Chr7:9394393`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C14
`Chr7:9395154`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B74
`Chr7:9395724`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A11,B13,B136
`Chr7:9398502`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A2,B131,B56,B96
`Chr7:9398809`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B140
`Chr7:9398912`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C46
`Chr7:9398921`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C32,C68
`Chr7:9399404`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B121,B41,C10,C42

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057773005.1

1020 aa

510

1020

DEAD_2

ARCH_RTEL1

Helicase_C_2

HHD_RTEL1

PF06733 DEAD_2 99-259 aa PF23109 ARCH_RTEL1 265-429 aa PF13307 Helicase_C_2 514-705 aa PF23116 HHD_RTEL1 883-1011 aa

XP_057773006.1

874 aa

437

874

DEAD_2

ARCH_RTEL1

Helicase_C_2

HHD_RTEL1

PF06733 DEAD_2 48-113 aa PF23109 ARCH_RTEL1 119-283 aa PF13307 Helicase_C_2 368-559 aa PF23116 HHD_RTEL1 737-865 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057773005.1`	Pfam	`PF06733`	DEAD_2	Family	99	259	1e-51	175.7	DEAD_2
`XP_057773005.1`	Pfam	`PF23109`	ARCH_RTEL1	Domain	265	429	5.5e-38	131.5	RTEL1 helicase, ARCH domain
`XP_057773005.1`	Pfam	`PF13307`	Helicase_C_2	Domain	514	705	2.5e-49	168.3	Helicase C-terminal domain
`XP_057773005.1`	Pfam	`PF23116`	HHD_RTEL1	Domain	883	1011	1.3e-09	39.5	RTEL1, HHD domain
`XP_057773006.1`	Pfam	`PF06733`	DEAD_2	Family	48	113	1.6e-22	80.7	DEAD_2
`XP_057773006.1`	Pfam	`PF23109`	ARCH_RTEL1	Domain	119	283	4.8e-38	131.7	RTEL1 helicase, ARCH domain
`XP_057773006.1`	Pfam	`PF13307`	Helicase_C_2	Domain	368	559	2.8e-49	168.2	Helicase C-terminal domain
`XP_057773006.1`	Pfam	`PF23116`	HHD_RTEL1	Domain	737	865	3.7e-10	41.2	RTEL1, HHD domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057917022.1
AAAATGGCGGGAAAATGGAAGAACGCGATTGGGGATTTTGGTTGGGAGTAGTAATATAGGGTTTCATCAAGAACAAAATTAATTAATCCGATTCTACAGCCACGAGGAGAAGTGTCTGCGAATTCGCAATGCCGACGTACAATATTAGGGGTATCAATGTGGATTTTCCTTACGAGGCGTATGAATGCCAGCTTGTTTACATGGAAAAAGTCATCGAATCTCTTCAAAGCAAAAGTAATGCTCTATTAGAGAGTCCAACT...

XM_057917023.1
AGTAGCATCAGAGGAAGTCAGTCTGTAGATGAAGATCTACCGCAATCCCAATCTTCTCAGTTTCCCACAATAATTTACACATCACGCACCCACAGCCAGATTAAGCAAGTGGTTAAAGAGTTGAAGAGGTCCAACTACAGGCCCAAAATGGTGGTGTTAGGATCTCGAGAGCAATTGTGTATTCACGACCAAGTAAGTCTACTTCGTGGAAAGGCGCAAACAAATGCTTGCCATGCCCTATGCAAAAAGCGCACAAAACG...

CDS

2 records

下载 CDS FASTA

LOC130992404
ATGCCGACGTACAATATTAGGGGTATCAATGTGGATTTTCCTTACGAGGCGTATGAATGCCAGCTTGTTTACATGGAAAAAGTCATCGAATCTCTTCAAAGCAAAAGTAATGCTCTATTAGAGAGTCCAACTGGAACAGGAAAGACATTATGCCTTCTATGCGCCACATTAGCTTGGAGGAGAAGTTTTGGCGAGTTTTCTAGAGGCCGGAACGATAAAAGTAGCATCAGAGGAAGTCAGTCTGTAGATGAAGATCTACC...

LOC130992404
ATGCTTGCCATGCCCTATGCAAAAAGCGCACAAAACGATTTTGTGCTAATTTTTCGCGTGTTGCAGAATTTGTCAAGAAGAATCCTGGTATTGGAGATGATCCTATTGATATTGAGGACTTGGTCAATATTGGAAAAAGCTCGGGATCGTAGGTGCCCTTATTACCTATCACGGGAGCTTCATAAGGATGTTGACATCTTATTCGCACCTTACAACTATCTTATTGATCGTGGGAATCGAAAATCTCTAAAGATTGACTG...

Protein

2 records

下载 Protein FASTA

XP_057773005.1
MPTYNIRGINVDFPYEAYECQLVYMEKVIESLQSKSNALLESPTGTGKTLCLLCATLAWRRSFGEFSRGRNDKSSIRGSQSVDEDLPQSQSSQFPTIIYTSRTHSQIKQVVKELKRSNYRPKMVVLGSREQLCIHDQVSLLRGKAQTNACHALCKKRTKRFCANFSRVAEFVKKNPGIGDDPIDIEDLVNIGKSSGSCPYYLSRELHKDVDILFAPYNYLIDRGNRKSLKIDWNKCILIFDEAHNLESLCAEAASFDLPS...

XP_057773006.1
MLAMPYAKSAQNDFVLIFRVLQNLSRRILVLEMILLILRTWSILEKARDRRCPYYLSRELHKDVDILFAPYNYLIDRGNRKSLKIDWNKCILIFDEAHNLESLCAEAASFDLPSGLLTACISEAKNCIDLSVTRRDTSNDKSCSPDDFAILRALLLKLEKRIAEVPIASKELGFTKDGPYIYELLSELNITQQTANMLMGIIEKACELLEEDGNVTGSGGSHKMNGTVCRLESIGDIFGLIFKNNCTAHAQYYRLHVQEV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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