Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G003771`

染色体: Chr07 坐标: 46136272-46148760 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G003771`
名称	SmilChr07G003771
描述	regulator of nonsense transcripts 1 homolog
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	46136272 - 46148760 / `+`

ID 对照

NCBI Gene ID	`LOC130992782`
GeneID	`130992782`
locus_tag	`-`
NCBI Name	`LOC130992782`
原始查询	`LOC130992782`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	regulator of nonsense transcripts 1 homolog
产物	regulator of nonsense transcripts 1 homolog
Arabidopsis	`AT5G47010` (LBA1) RNA helicase [Source:NCBI gene (formerly Entrezgene);Acc:834747] identity=80.6; qcov=0.992; evalue=0; confidence=high
Rice	`Os07g0495900` - identity=84.8; qcov=0.878; evalue=0; confidence=high
GO	GO:0000184 (nuclear-transcribed mRNA catabolic process, nonsense-mediated decay); GO:0003677 (DNA binding); GO:0003723 (RNA binding); GO:0003724 (RNA helicase activity); GO:0005524 (ATP binding); GO:0005737 (cytoplasm); GO:0008270 (zinc ion binding); GO:0016787 (hydrolase activity)
KEGG	-
Pfam	PF04851 (ResIII); PF09416 (UPF1_Zn_bind); PF13086 (AAA_11); PF13087 (AAA_12); PF13245 (AAA_19); PF13604 (AAA_30); PF18141 (UPF1_1B_dom)
InterPro	-
eggNOG	-
NR	GeneID:130992782

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057773519.1`
2	Cytosol	细胞质基质	1.00000	`XP_057773519.1`
3	Cytoplasmic granule	细胞质颗粒	0.80000	`XP_057773519.1`
4	Cytoplasmic ribonucleoprotein granule	Cytoplasmic ribonucleoprotein granule	0.60000	`XP_057773519.1`
5	Nucleus	细胞核	0.40000	`XP_057773519.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:46136509`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C27,C63,D11
`Chr7:46136532`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B111,B27,B57
`Chr7:46136553`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B11,B17,B73,C30
`Chr7:46136634`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B37,B44,B69
`Chr7:46136889`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B47,B8,B93,C31
`Chr7:46137225`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C60
`Chr7:46137348`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B42,B43,B44,B58,C58
`Chr7:46137654`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr7:46141677`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B30
`Chr7:46143683`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr7:46144599`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C6
`Chr7:46145208`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B129

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057773519.1

1270 aa

635

1270

UPF1_Zn_bind

UPF1_1B_dom

ResIII

AAA_11

AAA_30

AAA_19

AAA_11

AAA_12

PF09416 UPF1_Zn_bind 135-288 aa PF18141 UPF1_1B_dom 340-429 aa PF04851 ResIII 485-555 aa PF13086 AAA_11 485-603 aa PF13604 AAA_30 485-686 aa PF13245 AAA_19 492-686 aa PF13086 AAA_11 586-688 aa PF13087 AAA_12 697-893 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057773519.1`	Pfam	`PF09416`	UPF1_Zn_bind	Domain	135	288	2.2e-72	242.7	RNA helicase (UPF2 interacting domain)
`XP_057773519.1`	Pfam	`PF18141`	UPF1_1B_dom	Domain	340	429	9.3e-27	93.6	RNA helicase UPF1, 1B domain
`XP_057773519.1`	Pfam	`PF04851`	ResIII	Family	485	555	2.8e-06	28.1	Type III restriction enzyme, res subunit
`XP_057773519.1`	Pfam	`PF13086`	AAA_11	Domain	485	603	8.8e-53	180.4	AAA domain
`XP_057773519.1`	Pfam	`PF13604`	AAA_30	Domain	485	686	2.4e-15	57.5	AAA domain
`XP_057773519.1`	Pfam	`PF13245`	AAA_19	Domain	492	686	9.6e-12	45.9	AAA domain
`XP_057773519.1`	Pfam	`PF13086`	AAA_11	Domain	586	688	8.8e-53	180.4	AAA domain
`XP_057773519.1`	Pfam	`PF13087`	AAA_12	Domain	697	893	3.8e-62	210.1	AAA domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057917536.1
TTTCAGCAGAAACACAGCATCATCAAAATTCCCCAATCGCTCCCCACTCGCCGCGCTTAACCCCTTTCTCCCTCCCTGCGACCAAACCCTAACCCTAATCCCCCCTCAGATTTTTCCCCAATCCACCACAATTTCGTGATCTCCGCTCCCACCTCGTCGATTTCTCGGGCAAGAGGCATGGATTCGCAGCCCAGCAATCTGTACGAGACGGCGTCGCAGCCGGACACCGGCAACGACGCCTACACATTCCTCGAGTTCAA...

CDS

1 records

下载 CDS FASTA

LOC130992782
ATGGATTCGCAGCCCAGCAATCTGTACGAGACGGCGTCGCAGCCGGACACCGGCAACGACGCCTACACATTCCTCGAGTTCAACACTCAAGGCGAGGAGGACTTCGATTACCCCGAATTCCAAGAGCTATCGCAGCCTATTCGATCATCCACCGCCGTCTGGCCCACGCCGTCCGATTCTATCTCCGCCGCGGAGCTTCCCTCCTCTTCTGAAGCCTCCCACTCCACAGTCAAGCCCCGCGCTGCAAGTGCTGGCGCTCC...

Protein

1 records

下载 Protein FASTA

XP_057773519.1
MDSQPSNLYETASQPDTGNDAYTFLEFNTQGEEDFDYPEFQELSQPIRSSTAVWPTPSDSISAAELPSSSEASHSTVKPRAASAGAPNNNSTSNSNSKETGVVEALAAGMSGLNFEDTGGDDELFEYGKGDFTEHACRYCGVTNPACVVRCNVPSCRKWFCNSRGNTSGSHIVNHLVRAKHKEVCLHKDSPLGETILECYNCGCRNVFLLGFISAKTESVVVLLCREPCLSVNALKDMNWDLSQWCPLIDDRCFLQWLLK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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