Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G003350`

染色体: Chr01 坐标: 52257526-52261602 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G003350`
名称	SmilChr01G003350
描述	F-box protein SKP2B-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	52257526 - 52261602 / `+`

ID 对照

NCBI Gene ID	`LOC130992896`
GeneID	`130992896`
locus_tag	`-`
NCBI Name	`LOC130992896`
原始查询	`LOC130992896`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	F-box protein SKP2B-like
产物	F-box protein SKP2B-like
Arabidopsis	`AT1G77000` (SKP2B) RNI-like superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:844036] identity=69.8; qcov=0.989; evalue=0; confidence=high
Rice	`Os05g0425700` (OsFbox258) - identity=70.5; qcov=0.956; evalue=1.76e-173; confidence=high
GO	GO:0005515 (protein binding); GO:0019005 (SCF ubiquitin ligase complex); GO:0031146 (SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)
KEGG	smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00646 (F-box); PF12937 (F-box-like); PF13516 (LRR_6); PF25372 (LRR_FBXL15); PF29594 (LRR_SKP2)
InterPro	-
eggNOG	-
NR	GeneID:130992896

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	0.40000	`XP_057773646.1`
2	Cytoplasm	细胞质	0.40000	`XP_057773646.1`
3	Cytosol	细胞质基质	0.40000	`XP_057773646.1`
4	Mitochondrion	线粒体	0.20000	`XP_057773646.1`
5	Chromosome	染色体	0.00000	`XP_057773646.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:52257874`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B68
`Chr1:52257955`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C85,D7
`Chr1:52257961`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B15,B28,B51
`Chr1:52257969`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B103
`Chr1:52259245`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C47
`Chr1:52259295`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A9,B83,C41
`Chr1:52259432`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B69,C37,C82
`Chr1:52259724`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A24,B125,B38,C9
`Chr1:52260134`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B137,C16
`Chr1:52260194`	`CT`	`C`	1bp_deletion	frameshift_variant	1	C39
`Chr1:52260194`	`CT`	`C`	1bp_deletion	CDS_variant	1	C39
`Chr1:52260227`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B112,B131,B64,C16,D8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057773646.1

362 aa

181

362

F-box-like

F-box

LRR_SKP2

LRR_FBXL15

LRR_6

PF12937 F-box-like 30-63 aa PF00646 F-box 30-64 aa PF29594 LRR_SKP2 110-288 aa PF25372 LRR_FBXL15 144-280 aa PF13516 LRR_6 200-220 aa

XP_057773647.1

362 aa

181

362

F-box-like

F-box

LRR_SKP2

LRR_FBXL15

LRR_6

PF12937 F-box-like 30-63 aa PF00646 F-box 30-64 aa PF29594 LRR_SKP2 110-288 aa PF25372 LRR_FBXL15 144-280 aa PF13516 LRR_6 200-220 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057773646.1`	Pfam	`PF12937`	F-box-like	Domain	30	63	1.1e-07	32.2	F-box-like
`XP_057773646.1`	Pfam	`PF00646`	F-box	Domain	30	64	1.6e-05	25.3	F-box domain
`XP_057773646.1`	Pfam	`PF29594`	LRR_SKP2	Repeat	110	288	1.8e-25	90.4	SKP2 LRR domain
`XP_057773646.1`	Pfam	`PF25372`	LRR_FBXL15	Repeat	144	280	9.7e-17	61.2	F-box/LRR-repeat protein 15, leucine rich repeat domain
`XP_057773646.1`	Pfam	`PF13516`	LRR_6	Repeat	200	220	4.2e-14	52.1	Leucine Rich repeat
`XP_057773647.1`	Pfam	`PF12937`	F-box-like	Domain	30	63	1.1e-07	32.2	F-box-like
`XP_057773647.1`	Pfam	`PF00646`	F-box	Domain	30	64	1.6e-05	25.3	F-box domain
`XP_057773647.1`	Pfam	`PF29594`	LRR_SKP2	Repeat	110	288	1.8e-25	90.4	SKP2 LRR domain
`XP_057773647.1`	Pfam	`PF25372`	LRR_FBXL15	Repeat	144	280	9.7e-17	61.2	F-box/LRR-repeat protein 15, leucine rich repeat domain
`XP_057773647.1`	Pfam	`PF13516`	LRR_6	Repeat	200	220	4.2e-14	52.1	Leucine Rich repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057917664.1
GACCGATACGTACAACAATCGAAGACACAATTTCAATATTTGACTCATCTCGAAAAAGAAAAAAAAAATCTCCACCCCCATATTTTTCACGCTCATTGAAGCAGTCCCAAAATATCATTCAAGAAAATATTAAAGTATATATATTGCGGAAGATAATTGTTTTGCTTATCCTTTGATTTTCTGGTTGACAGAATTAAAAAAGGTAGCAGCTTTATGATCTTTAGCTTTTATGCTTTTGGATTCTATATAATTAAGGAGGG...

XM_057917663.1
CGATACGTACAACAATCGAAGACACAATTTCAATATTTGACTCATCTCGAAAAAGAAAAAAAAAATCTCCACCCCCATATTTTTCACGCTCATTGAAGCAGTCCCAAAATATCATTCAAGAAAATATTAAAGTATATATATTGCGGAAGATAATTGTTTTGCTTATCCTTTGATTTTCTGGTTGACAGAATTAAAAAAGGTAGCAGCTTTATGATCTTTAGCTTTTATGCTTTTGGATTCTATATAATTAAGGAGGGTGC...

CDS

2 records

下载 CDS FASTA

LOC130992896
ATGGGAGGAGCAGAGGGCCTTGATTTCTCCTTTGAAAATATGGAGATTATATGCGGCGGCGGCGGCGGCGGGGTGACGCTTAGTGAGTGGAAGGATATACCGGTGGAGCTGTTGATGAGGATTCTGTCTCTGCTGGATGATCGGACGGCGGTGGCGGCGGCCGGGGTTTGCCGTGGTTGGAGAGATGCCCTTTGCTGGGGCCTCACTCATCTCTCTCTCTCTTGGTGCAAGAGAAACATGAACAATTTGGTCCTATCACT...

Protein

2 records

下载 Protein FASTA

XP_057773646.1
MGGAEGLDFSFENMEIICGGGGGGVTLSEWKDIPVELLMRILSLLDDRTAVAAAGVCRGWRDALCWGLTHLSLSWCKRNMNNLVLSLAPKFTKLQSLILRQDVPQLQDNAVEEIASHCHELQELDLSKSFLLRDPSLYAIARGCPNLIKLNISGCSAFSDTALGYLTGHCRKLKSLNLCGCVGTASDRALKAIGYNCNGLQYLNLGWCDRVGDEGIKSLAYGCPDLRAIDLCGCVLITDDSVIALADSCLHLRSLGLYYC...

XP_057773647.1
MGGAEGLDFSFENMEIICGGGGGGVTLSEWKDIPVELLMRILSLLDDRTAVAAAGVCRGWRDALCWGLTHLSLSWCKRNMNNLVLSLAPKFTKLQSLILRQDVPQLQDNAVEEIASHCHELQELDLSKSFLLRDPSLYAIARGCPNLIKLNISGCSAFSDTALGYLTGHCRKLKSLNLCGCVGTASDRALKAIGYNCNGLQYLNLGWCDRVGDEGIKSLAYGCPDLRAIDLCGCVLITDDSVIALADSCLHLRSLGLYYC...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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