Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002058`

染色体: Chr07 坐标: 18716210-18721959 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002058`
名称	SmilChr07G002058
描述	E3 ubiquitin-protein ligase ORTHRUS 2-like
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	18716210 - 18721959 / `-`

ID 对照

NCBI Gene ID	`LOC130993138`
GeneID	`130993138`
locus_tag	`-`
NCBI Name	`LOC130993138`
原始查询	`LOC130993138`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	E3 ubiquitin-protein ligase ORTHRUS 2-like
产物	E3 ubiquitin-protein ligase ORTHRUS 2-like
Arabidopsis	`AT1G57820` (VIM1) Zinc finger (C3HC4-type RING finger) family protein [Source:NCBI gene (formerly Entrezgene);Acc:842157] identity=60; qcov=0.802; evalue=0; confidence=high
Rice	`Os05g0102600` (OsRFPHC-11) - identity=59.6; qcov=0.797; evalue=0; confidence=high
GO	GO:0016567 (protein ubiquitination); GO:0044027 (negative regulation of gene expression via chromosomal CpG island methylation); GO:0061630 (ubiquitin protein ligase activity)
KEGG	-
Pfam	PF00097 (zf-C3HC4); PF02182 (SAD_SRA); PF13445 (zf-RING_UBOX); PF13639 (zf-RING_2); PF13920 (zf-C3HC4_3); PF13923 (zf-C3HC4_2); PF15227 (zf-C3HC4_4)
InterPro	-
eggNOG	-
NR	GeneID:130993138

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057773901.1`
2	Nucleoplasm	核质	0.20000	`XP_057773901.1`
3	Chromosome	染色体	0.00000	`XP_057773901.1`
4	Centromere	着丝粒	0.00000	`XP_057773901.1`
5	Chromatin	染色质	0.00000	`XP_057773901.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:18716668`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B19,C19
`Chr7:18716680`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C46,C83
`Chr7:18716759`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B72
`Chr7:18716942`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr7:18716988`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr7:18717032`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B34,C3
`Chr7:18717038`	`GTT`	`G`	2bp_deletion	frameshift_variant	1	B112
`Chr7:18717038`	`GTT`	`G`	2bp_deletion	CDS_variant	1	B112
`Chr7:18717126`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr7:18717460`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C30,D9
`Chr7:18717479`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C52
`Chr7:18717518`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B126

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057773901.1

798 aa

399

798

zf-C3HC4_3

zf-C3HC4_2

zf-RING_2

zf-RING_UBOX

zf-C3HC4

zf-C3HC4_4

SAD_SRA

zf-RING_UBOX

zf-C3HC4

PF13920 zf-C3HC4_3 136-181 aa PF13923 zf-C3HC4_2 137-177 aa PF13639 zf-RING_2 137-178 aa PF13445 zf-RING_UBOX 138-174 aa PF00097 zf-C3HC4 138-177 aa PF15227 zf-C3HC4_4 138-177 aa PF02182 SAD_SRA 270-418 aa PF13445 zf-RING_UBOX 510-541 aa PF00097 zf-C3HC4 510-566 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057773901.1`	Pfam	`PF13920`	zf-C3HC4_3	Domain	136	181	1e-08	35.5	Zinc finger, C3HC4 type (RING finger)
`XP_057773901.1`	Pfam	`PF13923`	zf-C3HC4_2	Domain	137	177	7.9e-09	35.9	Zinc finger, C3HC4 type (RING finger)
`XP_057773901.1`	Pfam	`PF13639`	zf-RING_2	Domain	137	178	5.6e-08	33.6	Ring finger domain
`XP_057773901.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	138	174	6.5e-15	55.6	RING-type zinc-finger
`XP_057773901.1`	Pfam	`PF00097`	zf-C3HC4	Domain	138	177	6.6e-09	36.2	Zinc finger, C3HC4 type (RING finger)
`XP_057773901.1`	Pfam	`PF15227`	zf-C3HC4_4	Domain	138	177	4.1e-08	33.9	zinc finger of C3HC4-type, RING
`XP_057773901.1`	Pfam	`PF02182`	SAD_SRA	Domain	270	418	1.4e-48	165.1	SAD/SRA domain
`XP_057773901.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	510	541	6.5e-15	55.6	RING-type zinc-finger
`XP_057773901.1`	Pfam	`PF00097`	zf-C3HC4	Domain	510	566	6.6e-09	36.2	Zinc finger, C3HC4 type (RING finger)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057917918.1
TGAAAAAATTCAAAAAGTTTCCTGAAAAATTAATTCCCGATTTCAAGTCCGCGCCAAAGACCCCCAAATTTCTCTCCTGTATTTAAGCAGCATACTCCCAGAACCAACCACTCACTCTACTCTCCACTTTCATCTCTTTCTTTATTATTTTCATCATAACTATTAATTGTATTTTAATCCAATGGCGCAAGTTAGCGACCTCCCGTGCGACGGCGACGGCTTCTGCATGCTCTGCAAGCAGAAGCCGCCGGAGGGGGAGA...

CDS

1 records

下载 CDS FASTA

LOC130993138
ATGGCGCAAGTTAGCGACCTCCCGTGCGACGGCGACGGCTTCTGCATGCTCTGCAAGCAGAAGCCGCCGGAGGGGGAGATCCTCACGTGCAAAACGTGCGTCACGCCGTGGCACGTCGCCTGCCTCGCCACCCGCCCCCTAACCCTAGCGGACACTGCTCACTGGGACTGCCCCGACTGCTCCGATCTCTCCGCCGCCGGTGCCTCCATGCCGGCCGTCTCTGGAGGGGGACTGGTGGATAAGATTCGCGAGATCGAGTC...

Protein

1 records

下载 Protein FASTA

XP_057773901.1
MAQVSDLPCDGDGFCMLCKQKPPEGEILTCKTCVTPWHVACLATRPLTLADTAHWDCPDCSDLSAAGASMPAVSGGGLVDKIREIESDASLTDREKAKRRQELLSGATEAEKAEGKDKETNAADAGGVLGILGDRFNCSICMQLLDRPVSTPCGHNFCLKCFQKWTGQQRMKSCAICRKMIPTKMAREPRINSAIVMAIRMAKASQPNYSGGPPKIYHFIHNQDRPDKAFTTERAKKTGKANACSGKIFVTIPSDFFGPI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器