Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002071`

染色体: Chr07 坐标: 18843047-18850454 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002071`
名称	SmilChr07G002071
描述	retinoblastoma-related protein
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	18843047 - 18850454 / `-`

ID 对照

NCBI Gene ID	`LOC130993153`
GeneID	`130993153`
locus_tag	`-`
NCBI Name	`LOC130993153`
原始查询	`LOC130993153`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	retinoblastoma-related protein
产物	retinoblastoma-related protein
Arabidopsis	`AT3G12280` (RBR1) retinoblastoma-related 1 [Source:NCBI gene (formerly Entrezgene);Acc:820408] identity=66.4; qcov=0.991; evalue=0; confidence=high
Rice	`Os08g0538700` (Orysa) - identity=62.3; qcov=0.966; evalue=0; confidence=high
GO	GO:0000785 (chromatin); GO:0000977 (RNA polymerase II transcription regulatory region sequence-specific DNA binding); GO:0005634 (nucleus); GO:0005667 (transcription regulator complex); GO:0006357 (regulation of transcription by RNA polymerase II); GO:0030154 (cell differentiation); GO:2000134 (negative regulation of G1/S transition of mitotic cell cycle)
KEGG	-
Pfam	PF01857 (RB_B); PF01858 (RB_A); PF11934 (DUF3452)
InterPro	-
eggNOG	-
NR	GeneID:130993153

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057773914.1`
2	Nucleoplasm	核质	0.60000	`XP_057773914.1`
3	Chromosome	染色体	0.00000	`XP_057773914.1`
4	Centromere	着丝粒	0.00000	`XP_057773914.1`
5	Chromatin	染色质	0.00000	`XP_057773914.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:18843288`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A8
`Chr7:18843299`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B91
`Chr7:18843318`	`TC`	`T`	1bp_deletion	frameshift_variant	3	A3,B80,C78
`Chr7:18843318`	`TC`	`T`	1bp_deletion	CDS_variant	3	A3,B80,C78
`Chr7:18843348`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr7:18844019`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C83
`Chr7:18845219`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C39
`Chr7:18845226`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B2,C6
`Chr7:18846520`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C52
`Chr7:18846941`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B99
`Chr7:18848791`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr7:18848844`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057773914.1

1000 aa

500

1000

DUF3452

RB_A

RB_B

PF11934 DUF3452 94-228 aa PF01858 RB_A 411-604 aa PF01857 RB_B 724-851 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057773914.1`	Pfam	`PF11934`	DUF3452	Family	94	228	2e-32	112.4	Domain of unknown function (DUF3452)
`XP_057773914.1`	Pfam	`PF01858`	RB_A	Domain	411	604	1.2e-63	215.3	Retinoblastoma-associated protein A domain
`XP_057773914.1`	Pfam	`PF01857`	RB_B	Domain	724	851	1.5e-41	142.5	Retinoblastoma-associated protein B domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057917931.1
GCGTTTCTATAAAAAAAATATCAAAATATCAACATTTTGAATTTATAGAGCTTAGATTGTACTCCATATACTTACAGATAATTCTTTCTTTTGCCCTTTTGATTGCATATAAAAAACAAAAAACCGCAGATTCGTAACTGTCCAAGATAATTATATCGAAAATAGTAGTATAAATTAACAATGATAATTTCTCAAAAAACAAAAAAATAACACAATGATAAAATAAAAATAACACAAAATTGCCAGCAAAAATAAAAAAT...

CDS

1 records

下载 CDS FASTA

LOC130993153
ATGGCTGAGCTGAATAATGTTTCAAGCCCTAATCGTGAGCGAGATGGAGGTGGAGCCACCATTGAAGCTCGATTTGCTCACTTCTGCAAGAATGATCTACTGTTAGATGACAACGACCTTTTGGAGCAAGCCACAAAGCTGTTCGGTCAAAGCAAGAGTCTTCTGTTAGCCAATCTATCCGCTATTGGAACTGGGACGCCGGATGAAGCAGAACGGTACTGGTTTGCGTTTGTCCTCTACTCAGCGAGAAGACTCAGTGA...

Protein

1 records

下载 Protein FASTA

XP_057773914.1
MAELNNVSSPNRERDGGGATIEARFAHFCKNDLLLDDNDLLEQATKLFGQSKSLLLANLSAIGTGTPDEAERYWFAFVLYSARRLSENVGPIEKGLNLCQLLRAARLSIVDFYKELHHFLIKVGSILSNLYGEDWEKRLEAMESHTNFVHLTLLSKKYERAFRDLFSMVDANDSKQLNVANISGHGSDYYRFGWLLFLALRVHVFRLCKDLVSCTHGLVSVLAILLIHVPARFRNFNLNDSERIVMKGDKADLLASLCNM...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

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