Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002078`

染色体: Chr07 坐标: 18890937-18897188 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002078`
名称	SmilChr07G002078
描述	DNA replication licensing factor MCM2
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	18890937 - 18897188 / `+`

ID 对照

NCBI Gene ID	`LOC130993159`
GeneID	`130993159`
locus_tag	`-`
NCBI Name	`LOC130993159`
原始查询	`LOC130993159`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA replication licensing factor MCM2
产物	DNA replication licensing factor MCM2
Arabidopsis	`AT1G44900` (MCM2) minichromosome maintenance (MCM2/3/5) family protein [Source:NCBI gene (formerly Entrezgene);Acc:841056] identity=76.7; qcov=0.962; evalue=0; confidence=high
Rice	`Os11g0484300` (OsMCM2) - identity=78.2; qcov=1; evalue=0; confidence=high
GO	GO:0000727 (double-strand break repair via break-induced replication); GO:0003697 (single-stranded DNA binding); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0006260 (DNA replication); GO:0006268 (GO:0006268); GO:0017116 (single-stranded DNA helicase activity); GO:0042555 (MCM complex); GO:0043138 (3'-5' DNA helicase activity); GO:1902975 (mitotic DNA replication initiation); GO:1905775 (GO:1905775)
KEGG	smil03030 (DNA replication - Salvia miltiorrhiza (redroot sage))
Pfam	PF00493 (MCM); PF01078 (Mg_chelatase); PF07728 (AAA_5); PF12619 (MCM2_N); PF14551 (MCM_N); PF17207 (MCM_OB); PF17855 (MCM_lid); PF23669 (WHD_MCM2)
InterPro	-
eggNOG	-
NR	GeneID:130993159

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057773920.1`
2	Chromosome	染色体	1.00000	`XP_057773920.1`
3	Centromere	着丝粒	0.00000	`XP_057773920.1`
4	Chromatin	染色质	0.00000	`XP_057773920.1`
5	Telomere	端粒	0.00000	`XP_057773920.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:18892459`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B2
`Chr7:18892501`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B30,B85,C2,C79,D9
`Chr7:18892711`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B72
`Chr7:18892772`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B10,C41,C74
`Chr7:18893520`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C51
`Chr7:18894899`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B66,D7
`Chr7:18895932`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A19,B75,C42
`Chr7:18896176`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B3
`Chr7:18896261`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B130,B36,B48,C5,D4

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057773920.1

955 aa

478

955

MCM2_N

MCM_N

MCM_OB

MCM

AAA_5

Mg_chelatase

MCM_lid

WHD_MCM2

PF12619 MCM2_N 60-176 aa PF14551 MCM_N 239-331 aa PF17207 MCM_OB 338-465 aa PF00493 MCM 506-728 aa PF07728 AAA_5 563-680 aa PF01078 Mg_chelatase 617-708 aa PF17855 MCM_lid 765-849 aa PF23669 WHD_MCM2 873-949 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057773920.1`	Pfam	`PF12619`	MCM2_N	Family	60	176	9.2e-15	56.0	Mini-chromosome maintenance protein 2
`XP_057773920.1`	Pfam	`PF14551`	MCM_N	Domain	239	331	1.5e-17	64.5	MCM N-terminal domain
`XP_057773920.1`	Pfam	`PF17207`	MCM_OB	Domain	338	465	2.5e-34	118.5	MCM OB domain
`XP_057773920.1`	Pfam	`PF00493`	MCM	Domain	506	728	1.6e-103	345.4	MCM P-loop domain
`XP_057773920.1`	Pfam	`PF07728`	AAA_5	Domain	563	680	2.4e-06	28.3	AAA domain (dynein-related subfamily)
`XP_057773920.1`	Pfam	`PF01078`	Mg_chelatase	Domain	617	708	6.5e-08	32.9	Magnesium chelatase, subunit ChlI
`XP_057773920.1`	Pfam	`PF17855`	MCM_lid	Domain	765	849	2.8e-25	89.3	MCM AAA-lid domain
`XP_057773920.1`	Pfam	`PF23669`	WHD_MCM2	Domain	873	949	3.1e-23	82.4	DNA replication licensing factor MCM2-like, winged-helix domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057917937.1
TGATATGGGCCTGTGCACCCGTGGAAGGTTTTGGCGCGAAATATTCCCGCCAAAGCAACGGAATAAGGGGGGATATGTCGATGCCCTAGTCGAAAACCGCTTCTCACTCCGGCAAGCCACATTTCTCTATCTTCTTCAAACACAGAGTCTTCTGCAGAGCGACGATGGCGGGCGACGACGATTCATCCAGATCGGGAGGCGACGGCAACGGGGCGGCGGCGAACGCGATTCCTCCGTCCACACCCGATTCTCCGACTTCG...

CDS

1 records

下载 CDS FASTA

LOC130993159
ATGGCGGGCGACGACGATTCATCCAGATCGGGAGGCGACGGCAACGGGGCGGCGGCGAACGCGATTCCTCCGTCCACACCCGATTCTCCGACTTCGGTCGGTTTCAACACGGACCAGCTGCCGTTCAACACCAGCCAGAATTACACTGACGACGACGATGAAGCGTCCGTTGATCCTGAGATCGTCAGGGACGACATCGAAGATGAACACCTCAACGAGGAAGAGGAGGAAGGAGAGGACCTCTTCAATGACAATTTCAT...

Protein

1 records

下载 Protein FASTA

XP_057773920.1
MAGDDDSSRSGGDGNGAAANAIPPSTPDSPTSVGFNTDQLPFNTSQNYTDDDDEASVDPEIVRDDIEDEHLNEEEEEGEDLFNDNFMEDYRGMGEQDQYEGLGIDDSLEDERDLDQIMADRRAAELELDAKEARVSQRKLPQLLHDQDTDDESYRPSKRTRADFRPPGTPGSMDDTDGMASSPGRSRGNSRDDVPMTDQTDDDPYDDEENDEPENAMYRVQGTLREWVTRDEVRRFIGKKFKGFLLTYVKPKSENEDFEY...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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