Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002207`

染色体: Chr07 坐标: 20319312-20322278 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002207`
名称	SmilChr07G002207
描述	cell division cycle 20.2, cofactor of APC complex-like
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	20319312 - 20322278 / `+`

ID 对照

NCBI Gene ID	`LOC130993288`
GeneID	`130993288`
locus_tag	`-`
NCBI Name	`LOC130993288`
原始查询	`LOC130993288`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	cell division cycle 20.2, cofactor of APC complex-like
产物	cell division cycle 20.2%2C cofactor of APC complex-like
Arabidopsis	`AT4G33270` (CDC20.1) Transducin family protein / WD-40 repeat family protein [Source:NCBI gene (formerly Entrezgene);Acc:829463] identity=77.7; qcov=1.01; evalue=0; confidence=high
Rice	`Os02g0700100` (OsWD40-51) - identity=73.9; qcov=0.938; evalue=0; confidence=high
GO	GO:0005515 (protein binding); GO:0005680 (anaphase-promoting complex); GO:0010997 (anaphase-promoting complex binding); GO:0031145 (anaphase-promoting complex-dependent catabolic process); GO:1904668 (positive regulation of ubiquitin protein ligase activity); GO:1905786 (positive regulation of anaphase-promoting complex-dependent catabolic process); GO:1990757 (ubiquitin ligase activator activity)
KEGG	smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00400 (WD40); PF12894 (ANAPC4_WD40); PF24807 (WD40_CDC20-Fz)
InterPro	-
eggNOG	-
NR	GeneID:130993288

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	0.80000	`XP_057774104.1`
2	Cytoskeleton	细胞骨架	0.40000	`XP_057774104.1`
3	Chromosome	染色体	0.20000	`XP_057774104.1`
4	Nucleoplasm	核质	0.20000	`XP_057774104.1`
5	Spindle	Spindle	0.20000	`XP_057774104.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:20319832`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B6,C67
`Chr7:20320917`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B140
`Chr7:20320964`	`C`	`CA`	1bp_insertion	frameshift_variant	2	B136,B139
`Chr7:20320964`	`C`	`CA`	1bp_insertion	CDS_variant	2	B136,B139
`Chr7:20321127`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B121,B6,C67
`Chr7:20321193`	`C`	`CGG`	2bp_insertion	frameshift_variant	1	C61
`Chr7:20321193`	`C`	`CGG`	2bp_insertion	CDS_variant	1	C61
`Chr7:20321415`	`T`	`TTA`	2bp_insertion	frameshift_variant	1	B131
`Chr7:20321415`	`T`	`TTA`	2bp_insertion	CDS_variant	1	B131
`Chr7:20321446`	`G`	`GT`	1bp_insertion	frameshift_variant	13	B11,B138,B14,B22,B51,B54,B88,B90,C13,C48,C58,C66,C84

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057774104.1

453 aa

226

453

WD40_CDC20-Fz

ANAPC4_WD40

WD40

PF24807 WD40_CDC20-Fz 128-425 aa PF12894 ANAPC4_WD40 175-231 aa PF00400 WD40 177-206 aa PF00400 WD40 255-290 aa PF00400 WD40 303-341 aa PF00400 WD40 390-426 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057774104.1`	Pfam	`PF24807`	WD40_CDC20-Fz	Repeat	128	425	4.3e-126	420.9	CDC20/Fizzy WD40 domain
`XP_057774104.1`	Pfam	`PF12894`	ANAPC4_WD40	Repeat	175	231	3.4e-17	63.2	Anaphase-promoting complex subunit 4 WD40 domain
`XP_057774104.1`	Pfam	`PF00400`	WD40	Repeat	177	206	2.6e-33	113.7	WD domain, G-beta repeat
`XP_057774104.1`	Pfam	`PF00400`	WD40	Repeat	255	290	2.6e-33	113.7	WD domain, G-beta repeat
`XP_057774104.1`	Pfam	`PF00400`	WD40	Repeat	303	341	2.6e-33	113.7	WD domain, G-beta repeat
`XP_057774104.1`	Pfam	`PF00400`	WD40	Repeat	390	426	2.6e-33	113.7	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057918121.1
CCTTGGCAGCGAGTAAATTTCGTCAAGTAAATCTCAACGGCTCTCTTCCTCGAATTCCTCCACAAATTAGCCGTTGGCGCCTTTCCATTCGAAAAAGCCCTCTCAAAACCCTAAACACAAAATCAATCCAATATAAAAACCCCTCAATTGAACCAGATTTCATTCACCCAACAAGCAATTTAATCTCTGTCTGCTGAATCGAGAAAAATCCCTCACGATCTGTCATCTCAATTACATACATCTGTTATTGTTTTTTGTAT...

CDS

1 records

下载 CDS FASTA

LOC130993288
ATGGAAACAGGAAACATGAACTCATCTTCCACACCAAACAAGAGTAAGTCGCAACTCCCGCTGCAAGAACAGCTCCTGCAAAGAAGAAATTCGAAGGAGAATTTGGATCGCTTCATACCGAATAGGTCGGCAATGGATTTCGACTATGCTCATTACATGCTTACAGGTAAGGAAAACCCAACTGCAAGCTCCTCTCCATCCAGAGAAGCATACAGGAAGCAGCTTGCAGAAACCTTCAACATGAACAGAAGTCGGATTTT...

Protein

1 records

下载 Protein FASTA

XP_057774104.1
METGNMNSSSTPNKSKSQLPLQEQLLQRRNSKENLDRFIPNRSAMDFDYAHYMLTGKENPTASSSPSREAYRKQLAETFNMNRSRILAFKNKPPTPVEAIPSDFSSAAHQVKSAKPRRHIPQTSEKTLDAPDLMDDYYLNLLDWGSSNVLSIALGHTVYLWDAPDGATSELVTIDEECGPITSVKWAPDGRHIAVGLNNSEVQLWDSTSNRMLRTLKGGHRSRVGAMDWNNHILTTGGMDGQIFNNDVRVRAHIVETYTG...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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