Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G002553`

染色体: Chr07 坐标: 24214138-24218001 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G002553`
名称	SmilChr07G002553
描述	ATP-citrate synthase alpha chain protein 1
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	24214138 - 24218001 / `+`

ID 对照

NCBI Gene ID	`LOC130993625`
GeneID	`130993625`
locus_tag	`-`
NCBI Name	`LOC130993625`
原始查询	`LOC130993625`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	ATP-citrate synthase alpha chain protein 1
产物	ATP-citrate synthase alpha chain protein 1
Arabidopsis	`AT1G10670` (ACLA-1) ATP-citrate lyase A-1 [Source:NCBI gene (formerly Entrezgene);Acc:837610] identity=85.1; qcov=1; evalue=0; confidence=high
Rice	`Os12g0566300` (ACLA-3) - identity=82; qcov=1; evalue=0; confidence=high
GO	GO:0004775 (succinate-CoA ligase (ADP-forming) activity); GO:0006099 (tricarboxylic acid cycle); GO:0006104 (succinyl-CoA metabolic process); GO:0042709 (succinate-CoA ligase complex)
KEGG	smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF08442 (ATP-grasp_2); PF16114 (Citrate_bind); PF24948 (Citrate_synth_N)
InterPro	-
eggNOG	-
NR	GeneID:130993625

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057774565.1`
2	Cytoplasm	细胞质	0.80000	`XP_057774565.1`
3	Nucleoplasm	核质	0.20000	`XP_057774565.1`
4	Nucleus	细胞核	0.00000	`XP_057774565.1`
5	Chromosome	染色体	0.00000	`XP_057774565.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:24214559`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C72
`Chr7:24215680`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B15,C51
`Chr7:24217111`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B106
`Chr7:24217595`	`C`	`CAA`	2bp_insertion	frameshift_variant	27	A4,B120,B125,B130,B31,B36,B45,B63,B69,B90,B97,C10,C30,C39,C51,C56,C60,C64,C65,C69,C72,C78,C81,C86,C87,D2,D4
`Chr7:24217612`	`C`	`CA`	1bp_insertion	frameshift_variant	31	A10,A18,A6,B120,B122,B125,B130,B14,B2,B31,B36,B38,B63,B69,B88,B90,B92,B94,B97,C10,C30,C38,C39,C51,C56,C60,C76,C81,C86,C87,D4

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057774565.1

436 aa

218

436

Citrate_synth_N

ATP-grasp_2

Citrate_bind

PF24948 Citrate_synth_N 2-230 aa PF08442 ATP-grasp_2 6-203 aa PF16114 Citrate_bind 241-403 aa

XP_057774566.1

423 aa

212

423

Citrate_synth_N

ATP-grasp_2

Citrate_bind

PF24948 Citrate_synth_N 2-230 aa PF08442 ATP-grasp_2 6-203 aa PF16114 Citrate_bind 241-417 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057774565.1`	Pfam	`PF24948`	Citrate_synth_N	Domain	2	230	1.5e-74	251.0	ATP-citrate synthase ATP-grasp domain
`XP_057774565.1`	Pfam	`PF08442`	ATP-grasp_2	Domain	6	203	4.9e-16	59.7	ATP-grasp domain
`XP_057774565.1`	Pfam	`PF16114`	Citrate_bind	Domain	241	403	3.1e-76	255.6	ATP citrate lyase citrate-binding
`XP_057774566.1`	Pfam	`PF24948`	Citrate_synth_N	Domain	2	230	1.4e-74	251.1	ATP-citrate synthase ATP-grasp domain
`XP_057774566.1`	Pfam	`PF08442`	ATP-grasp_2	Domain	6	203	1.4e-15	58.2	ATP-grasp domain
`XP_057774566.1`	Pfam	`PF16114`	Citrate_bind	Domain	241	417	2.4e-83	278.7	ATP citrate lyase citrate-binding

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057918583.1
GGAAGGAAACTAAAAATAAGTTAAATAAATAAGTAATTTAGTTGCATTTCATGGAATCATGTTTGTCTAACTATAAATATCGGTAGGTGGATTACAAGATTACAAGCTTTGAGTGTTGAGTCATACTAGTCTGCCAGTGTGTGCGCACCAGAAAATTCTTGCAACCTCCTCTGCGCATTCCTTCAATCAGTTAAAAAGGAAAAATGGCGAGGAAGAAGATCAGAGAGTATGACTCCAAGAGACTGTTGAAGGAGCATTTC...

XM_057918582.1
AAAAATAAGTTAAATAAATAAGTAATTTAGTTGCATTTCATGGAATCATGTTTGTCTAACTATAAATATCGGTAGGTGGATTACAAGATTACAAGCTTTGAGTGTTGAGTCATACTAGTCTGCCAGTGTGTGCGCACCAGAAAATTCTTGCAACCTCCTCTGCGCATTCCTTCAATCAGTTAAAAAGGAAAAATGGCGAGGAAGAAGATCAGAGAGTATGACTCCAAGAGACTGTTGAAGGAGCATTTCAAGAGGATTTC...

CDS

2 records

下载 CDS FASTA

LOC130993625
ATGGCGAGGAAGAAGATCAGAGAGTATGACTCCAAGAGACTGTTGAAGGAGCATTTCAAGAGGATTTCTGGATCCGATTTGGAAATCAAATCTGCCCAGGTGACCGAGTCTACTGACTTTAATCAACTAGTGGACAAGGAGCCCTGGCTTTCATCTACAAGATTGGTTGTTAAACCAGATATGCTGTTTGGGAAACGTGGTAAAAGTGGTCTTGTTGCTTTGAACCTGGATTTGGCTGGAGTTGCTGCTTTTGTGAAAGA...

Protein

2 records

下载 Protein FASTA

XP_057774565.1
MARKKIREYDSKRLLKEHFKRISGSDLEIKSAQVTESTDFNQLVDKEPWLSSTRLVVKPDMLFGKRGKSGLVALNLDLAGVAAFVKERLGKEVEMGGCKGPITTFIVEPFIPHNEEFYLNIVSDRLGCSISFSECGGIDIEENWDKVKTIFVPTGVSFTSELCAPLVATLPLEVKPVIEEFITFIYALFLDLDFTFLEMNPFTLVNGKPYPLDMRGELDDTAAFKNFKKWGNIEFPMPFGRVMSPTESFIHGLDEKTSAS...

XP_057774566.1
MARKKIREYDSKRLLKEHFKRISGSDLEIKSAQVTESTDFNQLVDKEPWLSSTRLVVKPDMLFGKRGKSGLVALNLDLAGVAAFVKERLGKEVEMGGCKGPITTFIVEPFIPHNEEFYLNIVSDRLGCSISFSECGGIDIEENWDKVKTIFVPTGVSFTSELCAPLVATLPLEVKPVIEEFITFIYALFLDLDFTFLEMNPFTLVNGKPYPLDMRGELDDTAAFKNFKKWGNIEFPMPFGRVMSPTESFIHGLDEKTSAS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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