Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G001640`

染色体: Chr07 坐标: 13834601-13837969 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G001640`
名称	SmilChr07G001640
描述	bifunctional protein FolD 2-like
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	13834601 - 13837969 / `+`

ID 对照

NCBI Gene ID	`LOC130995344`
GeneID	`130995344`
locus_tag	`-`
NCBI Name	`LOC130995344`
原始查询	`LOC130995344`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	bifunctional protein FolD 2-like
产物	bifunctional protein FolD 2-like
Arabidopsis	`AT3G12290` (AT3G12290) Amino acid dehydrogenase family protein [Source:NCBI gene (formerly Entrezgene);Acc:820409] identity=82.8; qcov=0.988; evalue=2.62e-142; confidence=high
Rice	`Os05g0150800` - identity=81.4; qcov=0.983; evalue=1.36e-142; confidence=high
GO	GO:0004477 (methenyltetrahydrofolate cyclohydrolase activity); GO:0004488 (methylenetetrahydrofolate dehydrogenase (NADP+) activity); GO:0005829 (cytosol); GO:0035999 (tetrahydrofolate interconversion)
KEGG	-
Pfam	PF00763 (THF_DHG_CYH); PF02882 (THF_DHG_CYH_C)
InterPro	-
eggNOG	-
NR	GeneID:130995344

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057776578.1`
2	Cytoplasm	细胞质	0.80000	`XP_057776578.1`
3	Mitochondrion	线粒体	0.60000	`XP_057776580.1`
4	Nucleus	细胞核	0.00000	`XP_057776578.1`
5	Chromosome	染色体	0.00000	`XP_057776578.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:13835743`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B123,B14,C77
`Chr7:13835785`	`GC`	`G`	1bp_deletion	frameshift_variant	1	B36
`Chr7:13835785`	`GC`	`G`	1bp_deletion	CDS_variant	1	B36

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057776578.1

296 aa

148

296

THF_DHG_CYH

THF_DHG_CYH_C

PF00763 THF_DHG_CYH 9-124 aa PF02882 THF_DHG_CYH_C 145-292 aa

XP_057776579.1

296 aa

148

296

THF_DHG_CYH

THF_DHG_CYH_C

PF00763 THF_DHG_CYH 9-124 aa PF02882 THF_DHG_CYH_C 145-292 aa

XP_057776580.1

241 aa

120

241

THF_DHG_CYH

THF_DHG_CYH_C

PF00763 THF_DHG_CYH 1-69 aa PF02882 THF_DHG_CYH_C 90-237 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057776578.1`	Pfam	`PF00763`	THF_DHG_CYH	Domain	9	124	1.3e-42	145.4	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
`XP_057776578.1`	Pfam	`PF02882`	THF_DHG_CYH_C	Domain	145	292	1.6e-60	203.5	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
`XP_057776579.1`	Pfam	`PF00763`	THF_DHG_CYH	Domain	9	124	1.3e-42	145.4	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
`XP_057776579.1`	Pfam	`PF02882`	THF_DHG_CYH_C	Domain	145	292	1.6e-60	203.5	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
`XP_057776580.1`	Pfam	`PF00763`	THF_DHG_CYH	Domain	1	69	1.5e-24	87.2	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
`XP_057776580.1`	Pfam	`PF02882`	THF_DHG_CYH_C	Domain	90	237	7.3e-61	204.7	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057920596.1
TGCCTCTACAATTGCATCAGTCCGCCTCTCTGACCTCCGCGGCTCTGGATGATGGGTTTGGTTTCTGAAAAATTGAGAAAATTTTGAAGAACTCTCGACAACTGCCACAGTTTTTGCCAATGTACAAGTTCGTAGGCGCGAAGTATAAATTTCCAAACAACAATTCTCGCTGCCAGATGCTGATGTTTATCTACACTACACAATCACGAATCACCGTTCAGTTGATCAGAATCTAGCAGCAAATCTCTGTGAACCCACAA...

XM_057920597.1
TTCTTCTCGTTCTTCTCCATCCACGATTTTTGAATTTTGTTGTATTTATCTGCTATTCAAATTGTACCTATTTATGGGTTGGTGAATTTTGAATTTTTCTTTTTTTATTTTGTTTAAAAGGAGGTTTCTTGGTATAATCCGATTTGAAAACTTAAGTTCGTTCAAAGTTTTGGAGAAAGGTTGAATGGTTTTCTTTTGCAGGGATGATGGGTTTGGTTTCTGAAAAATTGAGAAAATTTTGAAGAACTCTCGACAACTGC...

CDS

3 records

下载 CDS FASTA

LOC130995344
ATGTCGGATCACAAGGTCACTATAATCGACGGCAAAGCAGTCGCCCAAACAATCCGATCGGAGATCGCTGCCGAAGTCCGCCGCCTCTCCGAAACGTACGGCAAGGTTCCTGGTCTAGCTGTTGTGATTGTGGGGCAAAGGAAGGATTCACAGAGCTATGTGAATATGAAAAGGAAAGCTTGTGCAGAAGTTGGAATCAAGTCGATTGATTTGGACCTACCAGAGAATGTATCCGAAACTGAATTGATTAGCAAAGTTCA...

Protein

3 records

下载 Protein FASTA

XP_057776578.1
MSDHKVTIIDGKAVAQTIRSEIAAEVRRLSETYGKVPGLAVVIVGQRKDSQSYVNMKRKACAEVGIKSIDLDLPENVSETELISKVHELNVNPDVHGILVQLPLPKHINEEKILTEISLGKDVDGFHPLNIGKLAMKDRDPLFVPCTPKGCIELLTRHGITIKGKNAVVVGRSNIVGLPVSLLLLKEDATVTIVHSRTKEPESIVRNADIIIAAAGQAAMIKGSWIKPGAAVIDVGTNAVDDPSKKSGYRLVGDVDFQEA...

XP_057776579.1
MSDHKVTIIDGKAVAQTIRSEIAAEVRRLSETYGKVPGLAVVIVGQRKDSQSYVNMKRKACAEVGIKSIDLDLPENVSETELISKVHELNVNPDVHGILVQLPLPKHINEEKILTEISLGKDVDGFHPLNIGKLAMKDRDPLFVPCTPKGCIELLTRHGITIKGKNAVVVGRSNIVGLPVSLLLLKEDATVTIVHSRTKEPESIVRNADIIIAAAGQAAMIKGSWIKPGAAVIDVGTNAVDDPSKKSGYRLVGDVDFQEA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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