Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr07G003591`

染色体: Chr07 坐标: 41927245-41930577 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr07G003591`
名称	SmilChr07G003591
描述	adenine DNA glycosylase-like
染色体 / SeqID	Chr07 / NC_080393.1
坐标与链方向	41927245 - 41930577 / `-`

ID 对照

NCBI Gene ID	`LOC130996245`
GeneID	`130996245`
locus_tag	`-`
NCBI Name	`LOC130996245`
原始查询	`LOC130996245`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	adenine DNA glycosylase-like
产物	adenine DNA glycosylase-like
Arabidopsis	`AT4G12740` (AT4G12740) HhH-GPD base excision DNA repair family protein [Source:NCBI gene (formerly Entrezgene);Acc:826886] identity=59.4; qcov=0.867; evalue=2.66e-176; confidence=high
Rice	`Os12g0211400` - identity=57.7; qcov=0.851; evalue=5.13e-165; confidence=high
GO	GO:0000701 (purine-specific mismatch base pair DNA N-glycosylase activity); GO:0005634 (nucleus); GO:0006284 (base-excision repair); GO:0006298 (mismatch repair); GO:0032357 (oxidized purine DNA binding); GO:0034039 (8-oxo-7,8-dihydroguanine DNA N-glycosylase activity); GO:0035485 (adenine/guanine mispair binding)
KEGG	smil03410 (Base excision repair - Salvia miltiorrhiza (redroot sage))
Pfam	PF00730 (HhH-GPD); PF14815 (NUDIX_4)
InterPro	-
eggNOG	-
NR	GeneID:130996245

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057777738.1`
2	Chloroplast	叶绿体	1.00000	`XP_057777738.1`
3	Nucleus	细胞核	0.00000	`XP_057777738.1`
4	Chromosome	染色体	0.00000	`XP_057777738.1`
5	Centromere	着丝粒	0.00000	`XP_057777738.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr7:41927688`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B140,B72
`Chr7:41928428`	`G`	`A`	EMS_canonical_SNV	stop_gained	3	B42,B43,B80
`Chr7:41928428`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B42,B43,B80
`Chr7:41928503`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B128,C19,C61
`Chr7:41928505`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B37
`Chr7:41928545`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A5,B138
`Chr7:41928648`	`G`	`GGA`	2bp_insertion	frameshift_variant	70	A10,A14,A16,A19,A22,A3,A8,A9,B10,B107,B108,B119,B120,B121,B122,B124,B126,B133,B134,B137,B14,B18,B22,B26,B3,B30,B35,B37,B40,B46,B47,B56,B64,B66,B68,B70,B81,B82,B85,B88,B94,B96,C10,C13,C17,C22,C23,C24,C25,C32,C33,C36,C4,C41,C47,C48,C5,C52,C62,C63,C68,C73,C74,C76,C77,C8,C81,C87,C9,D4
`Chr7:41928699`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A5,B127,B130,B22,B44
`Chr7:41929008`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	D11
`Chr7:41929008`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr7:41929019`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B66
`Chr7:41929054`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B23,C10,C18,C3,C70

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057777738.1

495 aa

248

495

HhH-GPD

NUDIX_4

PF00730 HhH-GPD 116-249 aa PF14815 NUDIX_4 332-459 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057777738.1`	Pfam	`PF00730`	HhH-GPD	Domain	116	249	2.1e-24	86.7	HhH-GPD superfamily base excision DNA repair protein
`XP_057777738.1`	Pfam	`PF14815`	NUDIX_4	Domain	332	459	3.7e-15	56.5	NUDIX domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XR_009092458.1
AATTTGATTGTAGCAATGATTACCTCAGACTTGAAAATCAACTATTTAGCGGGAAAATTACATTCTCCACTCTTGCCTCCCACTCTCCCCATTCGCCTTCCTCACCACTCGCCGGCAGCCGCCGCCGCCGCCGCACTCACGATGAAGAGATGCCGGCAATCAAAATCCGTAGCAAAAGAGACATTCGATGTTGTTGACTTAGAAGATATCGGCTTCAGCAGAAACGATATTGAAGAAATCAGGGCTTCTCTGCTACAATG...

XM_057921755.1
ATATCCCTACCTTAACTCGTAGTAGAAATTTGATTGTAGCAATGATTACCTCAGACTTGAAAATCAACTATTTAGCGGGAAAATTACATTCTCCACTCTTGCCTCCCACTCTCCCCATTCGCCTTCCTCACCACTCGCCGGCAGCCGCCGCCGCCGCCGCACTCACGATGAAGAGATGCCGGCAATCAAAATCCGTAGCAAAAGAGACATTCGATGTTGTTGACTTAGAAGATATCGGCTTCAGCAGAAACGATATTGAA...

CDS

1 records

下载 CDS FASTA

LOC130996245
ATGATTACCTCAGACTTGAAAATCAACTATTTAGCGGGAAAATTACATTCTCCACTCTTGCCTCCCACTCTCCCCATTCGCCTTCCTCACCACTCGCCGGCAGCCGCCGCCGCCGCCGCACTCACGATGAAGAGATGCCGGCAATCAAAATCCGTAGCAAAAGAGACATTCGATGTTGTTGACTTAGAAGATATCGGCTTCAGCAGAAACGATATTGAAGAAATCAGGGCTTCTCTGCTACAATGGTACGACGAGAATCG...

Protein

1 records

下载 Protein FASTA

XP_057777738.1
MITSDLKINYLAGKLHSPLLPPTLPIRLPHHSPAAAAAAALTMKRCRQSKSVAKETFDVVDLEDIGFSRNDIEEIRASLLQWYDENRRDLPWRRISSKESKGGVEQRERKAYAVWVSEVMLQQTRVQTVIDYFNRWMEKWPTIHHLAQATIEEVNETWAGLGYYRRARFLLEGAQMIVESGGEFPNTASSLQMVKGIGSYTAGAIASIAFDEAVPVVDGNVVRVVTRLKAISANPKDSKTVKDIWELARKLVDPLRPGDF...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

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