Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G003531`

染色体: Chr08 坐标: 37903082-37908772 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G003531`
名称	SmilChr08G003531
描述	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	37903082 - 37908772 / `-`

ID 对照

NCBI Gene ID	`LOC130996647`
GeneID	`130996647`
locus_tag	`-`
NCBI Name	`LOC130996647`
原始查询	`LOC130996647`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic-like
产物	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase%2C chloroplastic-like
Arabidopsis	`AT2G36230` (APG10) Aldolase-type TIM barrel family protein [Source:NCBI gene (formerly Entrezgene);Acc:818195] identity=76.5; qcov=0.877; evalue=1.32e-155; confidence=high
Rice	`Os05g0400800` - identity=74.3; qcov=0.49; evalue=1.81e-80; confidence=medium
GO	GO:0000105 (L-histidine biosynthetic process); GO:0000162 (L-tryptophan biosynthetic process); GO:0003949 (1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity); GO:0005737 (cytoplasm)
KEGG	smil00340 (Histidine metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00977 (His_biosynth)
InterPro	-
eggNOG	-
NR	GeneID:130996647

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057777921.1`
2	Chloroplast stroma	叶绿体基质	0.80000	`XP_057777921.1`
3	Nucleus	细胞核	0.00000	`XP_057777921.1`
4	Chromosome	染色体	0.00000	`XP_057777921.1`
5	Centromere	着丝粒	0.00000	`XP_057777921.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:37903304`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B131,C41
`Chr8:37903414`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B114,C71
`Chr8:37903775`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C59,D11
`Chr8:37904039`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B123,C59,D11
`Chr8:37904089`	`G`	`A`	EMS_canonical_SNV	stop_gained	82	A11,A14,A15,A16,A18,A19,A4,A7,A8,B101,B107,B11,B12,B123,B124,B125,B126,B127,B13,B131,B136,B20,B23,B24,B29,B30,B32,B33,B4,B42,B48,B49,B5,B50,B51,B55,B57,B58,B59,B67,B71,B72,B73,B75,B77,B78,B80,B88,B94,B97,C1,C12,C14,C15,C20,C26,C27,C31,C33,C37,C38,C39,C4,C42,C45,C47,C51,C55,C60,C62,C64,C66,C71,C72,C73,C77,C78,C81,C85,C86,D11,D8
`Chr8:37904508`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B4
`Chr8:37904798`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A8,B20
`Chr8:37904805`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C59
`Chr8:37904820`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A8,B20
`Chr8:37905122`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A10,B13,C26,C42
`Chr8:37905173`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B131,C41
`Chr8:37905183`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B32,B9,B99,C3

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057777921.1

310 aa

155

310

His_biosynth

PF00977 His_biosynth 53-286 aa

XP_057777922.1

310 aa

155

310

His_biosynth

PF00977 His_biosynth 53-286 aa

XP_057777923.1

310 aa

155

310

His_biosynth

PF00977 His_biosynth 53-286 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057777921.1`	Pfam	`PF00977`	His_biosynth	Family	53	286	1.1e-30	107.5	Histidine biosynthesis protein
`XP_057777922.1`	Pfam	`PF00977`	His_biosynth	Family	53	286	1.1e-30	107.5	Histidine biosynthesis protein
`XP_057777923.1`	Pfam	`PF00977`	His_biosynth	Family	53	286	1.1e-30	107.5	Histidine biosynthesis protein

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057921939.1
AATGAAAATAAAGAAAATAAATAAAAGAAAATAGGGGCCCTAAATTTCTTTCATACTACTATCAGTGCCGCTCTTCTTCGCCATACTTCTTATTTCTCTTTTCTTCTTTTTGATTTCTTATCTTTTTATTTTTCTGTACTTGTAGTTGTCTTCGATCTTATCTTTGATTGTATTATTTGAAATCGCATCGAGAGCTAATCCTTGCTATCTAAGAGCTGGTCTGTGGATTCTTGGGGATTCTTTGGTGTAAGCCATTTGAA...

XM_057921938.1
TCCTTTAATTATGAGCCCCAAAGCTAAGTTGTTAAAAAAAAGCCCATTCATCATTTTAAAAAATAAGCCCATGGAATGAGCCCAAACCCTTATATCTGTTTCTTCTCAATAGCTCTCCCATTCTTTTCGAGTTTCAATCCCTCGGCAGCAACAGTCACAGGTAGCCACGGCCGCCGCCGTCGCCGTACACACTACACACCACCATCTCTCTAGCCTCTCGCCCTCTGTCTCACTTCTCCTTCACAAATTCTGGCGCGGCA...

CDS

3 records

下载 CDS FASTA

LOC130996647
ATGAGCATTCACAATCTTCAAGCGACTTCATGGAAGGATTTTACTGAGCTTCCTGCGGTGTATGCACCTCGAGGCAAGCAGACTTTCGTCCATGCTGCACCTTGGGTGGTCCAGAGAAGTCGAAGGCTATTGATACAATGTGCCGTCAAGTTTCGTCCTTGCATTGACATACATAAGGGGAAAGTGAAACAGATTGTTGGATCCACTCTTCGAGATTTTAAAGAGGGAGATTCAAGTCTTATCACTAATTACGAATCTGA...

Protein

3 records

下载 Protein FASTA

XP_057777921.1
MSIHNLQATSWKDFTELPAVYAPRGKQTFVHAAPWVVQRSRRLLIQCAVKFRPCIDIHKGKVKQIVGSTLRDFKEGDSSLITNYESDISAAEYAKMYKDDGLTGGHVIMLGADPLSKAAAVEALHAYPGGLQVGGGINTRNALTYIDEGASHVIVTSYVFSDGQVDFERLKELAQAVGKERLVLDLSCRKKDGRYAVVTDRWQKFTDVFLDQEVLNFLAGHADEFLVHGVDVEGKKLGIDEELVELLGRHSPIPVTYAGG...

XP_057777922.1
MSIHNLQATSWKDFTELPAVYAPRGKQTFVHAAPWVVQRSRRLLIQCAVKFRPCIDIHKGKVKQIVGSTLRDFKEGDSSLITNYESDISAAEYAKMYKDDGLTGGHVIMLGADPLSKAAAVEALHAYPGGLQVGGGINTRNALTYIDEGASHVIVTSYVFSDGQVDFERLKELAQAVGKERLVLDLSCRKKDGRYAVVTDRWQKFTDVFLDQEVLNFLAGHADEFLVHGVDVEGKKLGIDEELVELLGRHSPIPVTYAGG...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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