Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G002888`

染色体: Chr08 坐标: 28753037-28759926 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G002888`
名称	SmilChr08G002888
描述	dihydrolipoyl dehydrogenase 2, chloroplastic-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	28753037 - 28759926 / `-`

ID 对照

NCBI Gene ID	`LOC130997493`
GeneID	`130997493`
locus_tag	`-`
NCBI Name	`LOC130997493`
原始查询	`LOC130997493`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	dihydrolipoyl dehydrogenase 2, chloroplastic-like
产物	dihydrolipoyl dehydrogenase 2%2C chloroplastic-like
Arabidopsis	`AT4G16155` (AT4G16155) dihydrolipoamide dehydrogenase [Source:NCBI gene (formerly Entrezgene);Acc:827307] identity=82.4; qcov=0.996; evalue=0; confidence=high
Rice	`Os01g0337900` - identity=80.7; qcov=0.953; evalue=0; confidence=high
GO	GO:0004148 (dihydrolipoyl dehydrogenase (NADH) activity); GO:0005739 (mitochondrion); GO:0045252 (oxoglutarate dehydrogenase complex); GO:0050660 (flavin adenine dinucleotide binding)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00280 (Valine, leucine and isoleucine degradation - Salvia miltiorrhiza (redroot sage)); smil00310 (Lysine degradation - Salvia miltiorrhiza (redroot sage)); smil00380 (Tryptophan metabolism - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil00640 (Propanoate metabolism - Salvia miltiorrhiza (redroot sage)); smil00670 (One carbon pool by folate - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage))
Pfam	PF00070 (Pyr_redox); PF01134 (GIDA); PF02852 (Pyr_redox_dim); PF07992 (Pyr_redox_2)
InterPro	-
eggNOG	-
NR	GeneID:130997493

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057778804.1`
2	Mitochondrion	线粒体	0.40000	`XP_057778804.1`
3	Chloroplast stroma	叶绿体基质	0.20000	`XP_057778804.1`
4	Nucleus	细胞核	0.00000	`XP_057778804.1`
5	Chromosome	染色体	0.00000	`XP_057778804.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:28753364`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C32
`Chr8:28754791`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B12
`Chr8:28755913`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C26
`Chr8:28757570`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C30
`Chr8:28757847`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A22,B89,B99,D2,D6
`Chr8:28758060`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A22,B89,B99,D2,D6
`Chr8:28758129`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B111,B50,B73,C29
`Chr8:28758852`	`C`	`CTG`	2bp_insertion	frameshift_variant	1	B25
`Chr8:28758852`	`C`	`CTG`	2bp_insertion	CDS_variant	1	B25
`Chr8:28759619`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B110
`Chr8:28759653`	`TG`	`T`	1bp_deletion	frameshift_variant	1	C65
`Chr8:28759653`	`TG`	`T`	1bp_deletion	CDS_variant	1	C65

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057778804.1

570 aa

285

570

Pyr_redox_2

GIDA

Pyr_redox

Pyr_redox_dim

PF07992 Pyr_redox_2 84-419 aa PF01134 GIDA 85-144 aa PF00070 Pyr_redox 258-334 aa PF02852 Pyr_redox_dim 438-549 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057778804.1`	Pfam	`PF07992`	Pyr_redox_2	Domain	84	419	8.3e-58	196.8	Pyridine nucleotide-disulphide oxidoreductase
`XP_057778804.1`	Pfam	`PF01134`	GIDA	Family	85	144	8.6e-05	22.5	Glucose inhibited division protein A
`XP_057778804.1`	Pfam	`PF00070`	Pyr_redox	Domain	258	334	1.1e-16	61.8	Pyridine nucleotide-disulphide oxidoreductase
`XP_057778804.1`	Pfam	`PF02852`	Pyr_redox_dim	Domain	438	549	1.5e-31	109.5	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057922821.1
ATGCGATTGGTGTCGTAAATTAAATGAAAAAGAAGAAATGGAAAAGGTGTTTTGTTTTAGTTGAGCTGCAGAACCTGAAAACAATACTAAAAGAGTCTTAGCAAACTCCGCCATCCCTCAACGGACCTCCCAAAGCTCCACCGCCCCCATTTAAACCACCCCTCCTTCCCACACTGCGCATACTCATACTTCTCCTTCTCCAAAATGCACTCCGCCATTTCTCTCTCCTTCTCTTCTCCCTCGCCGATCACCCGATCCTC...

CDS

1 records

下载 CDS FASTA

LOC130997493
ATGCACTCCGCCATTTCTCTCTCCTTCTCTTCTCCCTCGCCGATCACCCGATCCTCCGCCGCCTCTTCCACCGCGCCGCGCTCGCTCCGCTTCTGCGGCCTCCGGAGGGAGGCATTCGGCGCCGGCGCCTCCCCTGATGCGTCTTCCTTGCGCTTAGCTCGTTTCAATTCGCGTTCCCAGCATTTCAATTTGAATGGAGTTCTGGCGGCCTTGAAAGGCAACGGCGCGCCATCGTCTGGCGGCTTCGACTACGATCTCGT...

Protein

1 records

下载 Protein FASTA

XP_057778804.1
MHSAISLSFSSPSPITRSSAASSTAPRSLRFCGLRREAFGAGASPDASSLRLARFNSRSQHFNLNGVLAALKGNGAPSSGGFDYDLVIIGAGVGGHGAALHAVEKGLKTAIIEGDIVGGTCVNRGCVPSKALLAVSGRMRELQNEQHMKSFGLQVAAAGYDRQKVADHANNLASKIRGNLTNSMKALGVDILTGFGTILGPQKLKFGKGDSGDKIITAKDIIVATGSVPLVPKGIEVDGKTVITSDHALKLEFVPQWIAI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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