Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G003893`

染色体: Chr01 坐标: 57225823-57234347 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G003893`
名称	SmilChr01G003893
描述	probable E3 ubiquitin-protein ligase ARI8
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	57225823 - 57234347 / `+`

ID 对照

NCBI Gene ID	`LOC130997704`
GeneID	`130997704`
locus_tag	`-`
NCBI Name	`LOC130997704`
原始查询	`LOC130997704`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	probable E3 ubiquitin-protein ligase ARI8
产物	probable E3 ubiquitin-protein ligase ARI8
Arabidopsis	`AT2G31510` (ARI7) IBR domain-containing protein [Source:NCBI gene (formerly Entrezgene);Acc:817709] identity=67.7; qcov=1.01; evalue=0; confidence=high
Rice	`Os08g0540300` (P0666G10.134) - identity=66.8; qcov=0.882; evalue=0; confidence=high
GO	GO:0000151 (ubiquitin ligase complex); GO:0000209 (protein polyubiquitination); GO:0005737 (cytoplasm); GO:0006511 (ubiquitin-dependent protein catabolic process); GO:0008270 (zinc ion binding); GO:0031624 (ubiquitin conjugating enzyme binding); GO:0032436 (positive regulation of proteasomal ubiquitin-dependent protein catabolic process); GO:0061630 (ubiquitin protein ligase activity)
KEGG	-
Pfam	PF00097 (zf-C3HC4); PF01485 (IBR); PF13445 (zf-RING_UBOX); PF19422 (Ariadne); PF21235 (UBA_ARI1); PF22191 (IBR_1); PF22605 (IBR_2)
InterPro	-
eggNOG	-
NR	GeneID:130997704

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057779089.1`
2	Nucleus	细胞核	0.80000	`XP_057779098.1`
3	Cytosol	细胞质基质	0.80000	`XP_057779098.1`
4	Chromosome	染色体	0.00000	`XP_057779089.1`
5	Centromere	着丝粒	0.00000	`XP_057779089.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:57226219`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A2
`Chr1:57226237`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C74
`Chr1:57227564`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A2,B13
`Chr1:57227789`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C19,C4
`Chr1:57227812`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B65
`Chr1:57228648`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C3
`Chr1:57229552`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A15,C78
`Chr1:57233859`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D4

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057779089.1

604 aa

302

604

UBA_ARI1

zf-RING_UBOX

zf-C3HC4

IBR

IBR_1

IBR_2

Ariadne

PF21235 UBA_ARI1 88-126 aa PF13445 zf-RING_UBOX 154-180 aa PF00097 zf-C3HC4 154-190 aa PF01485 IBR 223-285 aa PF01485 IBR 302-349 aa PF22191 IBR_1 307-347 aa PF22605 IBR_2 308-347 aa PF19422 Ariadne 386-536 aa

XP_057779098.1

474 aa

237

474

UBA_ARI1

zf-RING_UBOX

zf-C3HC4

IBR

IBR_1

IBR_2

PF21235 UBA_ARI1 88-126 aa PF13445 zf-RING_UBOX 154-180 aa PF00097 zf-C3HC4 154-190 aa PF01485 IBR 223-285 aa PF01485 IBR 302-349 aa PF22191 IBR_1 307-347 aa PF22605 IBR_2 308-347 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057779089.1`	Pfam	`PF21235`	UBA_ARI1	Domain	88	126	2.6e-09	37.4	E3 ubiquitin-protein ligase ARIH1, UBA-like domain
`XP_057779089.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	154	180	1.6e-05	25.5	RING-type zinc-finger
`XP_057779089.1`	Pfam	`PF00097`	zf-C3HC4	Domain	154	190	1.6e-05	25.4	Zinc finger, C3HC4 type (RING finger)
`XP_057779089.1`	Pfam	`PF01485`	IBR	Domain	223	285	6.7e-23	81.2	IBR domain, a half RING-finger domain
`XP_057779089.1`	Pfam	`PF01485`	IBR	Domain	302	349	6.7e-23	81.2	IBR domain, a half RING-finger domain
`XP_057779089.1`	Pfam	`PF22191`	IBR_1	Domain	307	347	4e-15	56.2	IBR domain
`XP_057779089.1`	Pfam	`PF22605`	IBR_2	Domain	308	347	3.4e-13	50.2	IBR domain
`XP_057779089.1`	Pfam	`PF19422`	Ariadne	Domain	386	536	1.2e-05	26.0	Ariadne domain
`XP_057779098.1`	Pfam	`PF21235`	UBA_ARI1	Domain	88	126	1.7e-09	38.0	E3 ubiquitin-protein ligase ARIH1, UBA-like domain
`XP_057779098.1`	Pfam	`PF13445`	zf-RING_UBOX	Domain	154	180	7.3e-06	26.6	RING-type zinc-finger
`XP_057779098.1`	Pfam	`PF00097`	zf-C3HC4	Domain	154	190	1.2e-05	25.8	Zinc finger, C3HC4 type (RING finger)
`XP_057779098.1`	Pfam	`PF01485`	IBR	Domain	223	285	7.2e-24	84.4	IBR domain, a half RING-finger domain
`XP_057779098.1`	Pfam	`PF01485`	IBR	Domain	302	349	7.2e-24	84.4	IBR domain, a half RING-finger domain
`XP_057779098.1`	Pfam	`PF22191`	IBR_1	Domain	307	347	4.3e-16	59.2	IBR domain
`XP_057779098.1`	Pfam	`PF22605`	IBR_2	Domain	308	347	2.5e-13	50.7	IBR domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057923106.1
TAATAAGTTTCCTAAATGTGCACGATTTAAGTCGTCCTAACAAGTAACAAGTCCAATCCATCTCCAATTGTAGTCTGTAGAACGAAAAGATGATCGCATCATTACTTTAGCCCTAATACTCGGTGGGAATCACTGATTTCCATCCCCCAATTCTCACCGTTCCTAAATTCTCTCAATTTTCTCTCTCTAGGGTTTTCTCAACTGAAAATCCGCGTATCGTGCGACCACCATGGAGTCTGAGGACGATATGCACGATGCCA...

XM_057923115.1
CGATTTAAGTCGTCCTAACAAGTAACAAGTCCAATCCATCTCCAATTGTAGTCTGTAGAACGAAAAGATGATCGCATCATTACTTTAGCCCTAATACTCGGTGGGAATCACTGATTTCCATCCCCCAATTCTCACCGTTCCTAAATTCTCTCAATTTTCTCTCTCTAGGGTTTTCTCAACTGAAAATCCGCGTATCGTGCGACCACCATGGAGTCTGAGGACGATATGCACGATGCCAATGAAGTAGCGTCGGTGGAGGA...

CDS

2 records

下载 CDS FASTA

LOC130997704
ATGGAGTCTGAGGACGATATGCACGATGCCAATGAAGTAGCGTCGGTGGAGGAGGATGATAACTACTACAGCGGCGGCGAGGACGACGATGATATGGACGAAGCTGGGGAAGACGAAGACTACGGCTACGACTATGCCGATGAAGAGGATGACGACGCTACCAATTACGACTTCATCGCCAACTCGGATGATGGCGATGACTCACTAGTCAGTCGGTCACAGAAGAACTATACTATCTTAAAAGAAGAAGATATACAACA...

Protein

2 records

下载 Protein FASTA

XP_057779089.1
MESEDDMHDANEVASVEEDDNYYSGGEDDDDMDEAGEDEDYGYDYADEEDDDATNYDFIANSDDGDDSLVSRSQKNYTILKEEDIQHRQFEDITKISTVLSIPREAACILLRRYNWSVNNVHEEWFADEENVRKAVGILEKPVVKSPNFKEVSCGICFENYSIDKLRTLACSHLFCDTCWKAYISTSINDGPGCLVLRCPDPSCGAAVGQDMIDNLASHEDKEKYRRYLLRSYVEDSRKIKWCPAPGCDSAVEFVVGSGS...

XP_057779098.1
MESEDDMHDANEVASVEEDDNYYSGGEDDDDMDEAGEDEDYGYDYADEEDDDATNYDFIANSDDGDDSLVSRSQKNYTILKEEDIQHRQFEDITKISTVLSIPREAACILLRRYNWSVNNVHEEWFADEENVRKAVGILEKPVVKSPNFKEVSCGICFENYSIDKLRTLACSHLFCDTCWKAYISTSINDGPGCLVLRCPDPSCGAAVGQDMIDNLASHEDKEKYRRYLLRSYVEDSRKIKWCPAPGCDSAVEFVVGSGS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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