Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G003329`

染色体: Chr08 坐标: 34589675-34594593 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G003329`
名称	SmilChr08G003329
描述	threonine dehydratase 1 biosynthetic, chloroplastic-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	34589675 - 34594593 / `+`

ID 对照

NCBI Gene ID	`LOC130997888`
GeneID	`130997888`
locus_tag	`-`
NCBI Name	`LOC130997888`
原始查询	`LOC130997888`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	threonine dehydratase 1 biosynthetic, chloroplastic-like
产物	threonine dehydratase 1 biosynthetic%2C chloroplastic-like
Arabidopsis	`AT3G10050` (OMR1) L-O-methylthreonine resistant 1 [Source:NCBI gene (formerly Entrezgene);Acc:820166] identity=75.7; qcov=0.874; evalue=0; confidence=high
Rice	`Os03g0713000` (OSJNBa0014G15.29) - identity=77.1; qcov=0.884; evalue=0; confidence=high
GO	GO:0004794 (threonine deaminase activity); GO:0006567 (L-threonine catabolic process); GO:0009097 (GO:0009097); GO:0030170 (pyridoxal phosphate binding)
KEGG	smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00290 (Valine, leucine and isoleucine biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00291 (PALP); PF00585 (Thr_dehydrat_C)
InterPro	-
eggNOG	-
NR	GeneID:130997888

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057779303.1`
2	Chloroplast stroma	叶绿体基质	0.80000	`XP_057779303.1`
3	Nucleus	细胞核	0.00000	`XP_057779303.1`
4	Chromosome	染色体	0.00000	`XP_057779303.1`
5	Centromere	着丝粒	0.00000	`XP_057779303.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:34589988`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B108
`Chr8:34590024`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B105,B51,C35,C64,C66
`Chr8:34590081`	`G`	`GT`	1bp_insertion	frameshift_variant	1	B33
`Chr8:34590081`	`G`	`GT`	1bp_insertion	CDS_variant	1	B33
`Chr8:34590118`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A18,B33,B49,C32,C68
`Chr8:34590190`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B106,B107,B17,C13,C24
`Chr8:34590311`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B44
`Chr8:34590359`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C11,C69
`Chr8:34591082`	`TG`	`T`	1bp_deletion	frameshift_variant	25	A15,A20,A21,A24,B118,B38,B39,B46,B56,B59,B66,B69,B8,B91,B96,B97,C11,C16,C22,C3,C4,C53,C69,C84,D4
`Chr8:34591296`	`TG`	`T`	1bp_deletion	frameshift_variant	3	B66,B8,C16
`Chr8:34591296`	`TG`	`T`	1bp_deletion	CDS_variant	3	B66,B8,C16
`Chr8:34591333`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B37

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057779303.1

612 aa

306

612

PALP

Thr_dehydrat_C

PF00291 PALP 128-415 aa PF00585 Thr_dehydrat_C 428-518 aa PF00585 Thr_dehydrat_C 524-607 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057779303.1`	Pfam	`PF00291`	PALP	Family	128	415	1.7e-81	274.5	Pyridoxal-phosphate dependent enzyme
`XP_057779303.1`	Pfam	`PF00585`	Thr_dehydrat_C	Domain	428	518	2.2e-48	162.7	C-terminal regulatory domain of Threonine dehydratase
`XP_057779303.1`	Pfam	`PF00585`	Thr_dehydrat_C	Domain	524	607	2.2e-48	162.7	C-terminal regulatory domain of Threonine dehydratase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057923320.1
TTGCTCGGGCAATTTAGTCCATAGGTTTTCAAATGGATTCCACGCTGGCCGAACTCGGTCGGCACTAATCACAAACCAAACGTGCTAGTTATTTTATTTATTTATTTTTGACATAGCGAAACGTGCTAATTATTATTGGATCCTCCCGTCACCCGCGGCTAACCCTATAGTTTTCACTCATAGGCATAGGCATAGGCATAGCAAAACCCTTTAGGTGAAGGTGACTATAAAAGGTTTTCATCTCCCTCGCATTTCCTGCC...

CDS

1 records

下载 CDS FASTA

LOC130997888
ATGGAAGTTCTCCGTTTTGCCCCTACGCAATCGCCTCTCCGCCGCGCCACATTTCCCGGCAGAGACTTCACGGAGGCTTCCTCAGCCACTATCCCGAGCTGCTGCCGACCGAGATCTTCTGCGGTCGCCAGGCTGTCAAAGCCGGCGCCGGCGCCGACTTTACCGACCGTTGAGGAGCTCCATTTGGCTGCGCCTTTGTCTCCTCCTCCACCTCCGGCGCCGGAGAAGCCGTTGTTGGTGGTTCCGCCGAGCTCACTGCA...

Protein

1 records

下载 Protein FASTA

XP_057779303.1
MEVLRFAPTQSPLRRATFPGRDFTEASSATIPSCCRPRSSAVARLSKPAPAPTLPTVEELHLAAPLSPPPPPAPEKPLLVVPPSSLQCESGYLVPNRYSGSCAAGVGSLNAMEYLTSILSSKVYDVAYESPLQVASKLSEKLGTNVWLKREDFQPVFSFKLRGAYNMMAKLSREQLERGVICSSAGNHAQGVALSAQKLGCNAVIVMPVTTPEIKWRSVERLGGTVVLVGDSYDEAQAFAKKQAEEEGRTFVPPFDHPDV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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