Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G003396`

染色体: Chr08 坐标: 35811181-35827137 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G003396`
名称	SmilChr08G003396
描述	serine/threonine-protein kinase CTR1
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	35811181 - 35827137 / `+`

ID 对照

NCBI Gene ID	`LOC130997943`
GeneID	`130997943`
locus_tag	`-`
NCBI Name	`LOC130997943`
原始查询	`LOC130997943`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	serine/threonine-protein kinase CTR1
产物	serine/threonine-protein kinase CTR1
Arabidopsis	`AT4G24480` (AT4G24480) Protein kinase superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:828550] identity=45; qcov=0.905; evalue=0; confidence=medium
Rice	`Os09g0566550` - identity=57.9; qcov=0.821; evalue=0; confidence=high
GO	GO:0004672 (protein kinase activity); GO:0005524 (ATP binding); GO:0006468 (protein phosphorylation)
KEGG	smil04016 (MAPK signaling pathway - plant - Salvia miltiorrhiza (redroot sage)); smil04075 (Plant hormone signal transduction - Salvia miltiorrhiza (redroot sage))
Pfam	PF00069 (Pkinase); PF07714 (PK_Tyr_Ser-Thr); PF14381 (EDR1_CTR1_ARMC3_pept)
InterPro	-
eggNOG	-
NR	GeneID:130997943

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057779363.1`
2	Cell membrane	细胞膜	0.80000	`XP_057779363.1`
3	Cytoplasm	细胞质	0.60000	`XP_057779363.1`
4	Nucleus	细胞核	0.00000	`XP_057779363.1`
5	Chromosome	染色体	0.00000	`XP_057779363.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:35811531`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D2
`Chr8:35811593`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B105,B51,C35
`Chr8:35816502`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B53
`Chr8:35816681`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A4,B131,C66
`Chr8:35816699`	`CAT`	`C`	2bp_deletion	frameshift_variant	33	A1,A4,A5,B10,B100,B105,B134,B17,B28,B32,B4,B5,B56,B61,B70,B71,B74,B75,B81,B91,B98,C11,C32,C37,C38,C49,C61,C71,C84,C9,D4,D7,D9
`Chr8:35816702`	`T`	`TGG`	2bp_insertion	frameshift_variant	34	A1,A4,A5,B10,B100,B105,B107,B134,B17,B28,B32,B4,B5,B56,B61,B70,B71,B74,B75,B81,B91,B98,C11,C32,C37,C38,C49,C61,C71,C84,C9,D4,D7,D9
`Chr8:35816713`	`GAC`	`G`	2bp_deletion	frameshift_variant	33	A1,A4,A5,B10,B100,B107,B134,B17,B28,B32,B33,B4,B5,B56,B61,B70,B71,B74,B75,B81,B91,B98,C11,C32,C37,C49,C61,C71,C84,C9,D4,D7,D9
`Chr8:35816716`	`G`	`GGA`	2bp_insertion	frameshift_variant	32	A1,A4,A5,B10,B100,B107,B134,B17,B28,B32,B4,B5,B56,B61,B70,B71,B74,B75,B81,B91,B98,C11,C32,C37,C49,C61,C71,C84,C9,D4,D7,D9
`Chr8:35816745`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B105,B51,C35
`Chr8:35816802`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B67,B70,C32,C37
`Chr8:35816860`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A22,B58,B64,B97,C84
`Chr8:35817846`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B122,B80,C79

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057779363.1

876 aa

438

876

EDR1_CTR1_ARMC3_pept

PK_Tyr_Ser-Thr

Pkinase

PF14381 EDR1_CTR1_ARMC3_pept 202-407 aa PF07714 PK_Tyr_Ser-Thr 602-855 aa PF00069 Pkinase 603-853 aa

XP_057779364.1

875 aa

438

875

EDR1_CTR1_ARMC3_pept

PK_Tyr_Ser-Thr

Pkinase

PF14381 EDR1_CTR1_ARMC3_pept 202-407 aa PF07714 PK_Tyr_Ser-Thr 602-855 aa PF00069 Pkinase 603-853 aa

XP_057779365.1

875 aa

438

875

EDR1_CTR1_ARMC3_pept

PK_Tyr_Ser-Thr

Pkinase

PF14381 EDR1_CTR1_ARMC3_pept 202-407 aa PF07714 PK_Tyr_Ser-Thr 602-855 aa PF00069 Pkinase 603-853 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057779363.1`	Pfam	`PF14381`	EDR1_CTR1_ARMC3_pept	Domain	202	407	5.2e-80	268.8	EDR1/CTR1/ARMC3, peptidase-like
`XP_057779363.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	602	855	1.6e-70	238.1	Protein tyrosine and serine/threonine kinase
`XP_057779363.1`	Pfam	`PF00069`	Pkinase	Domain	603	853	4.1e-55	187.7	Protein kinase domain
`XP_057779364.1`	Pfam	`PF14381`	EDR1_CTR1_ARMC3_pept	Domain	202	407	5.2e-80	268.8	EDR1/CTR1/ARMC3, peptidase-like
`XP_057779364.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	602	855	1.6e-70	238.1	Protein tyrosine and serine/threonine kinase
`XP_057779364.1`	Pfam	`PF00069`	Pkinase	Domain	603	853	4.1e-55	187.7	Protein kinase domain
`XP_057779365.1`	Pfam	`PF14381`	EDR1_CTR1_ARMC3_pept	Domain	202	407	5.2e-80	268.8	EDR1/CTR1/ARMC3, peptidase-like
`XP_057779365.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	602	855	1.6e-70	238.1	Protein tyrosine and serine/threonine kinase
`XP_057779365.1`	Pfam	`PF00069`	Pkinase	Domain	603	853	4.1e-55	187.7	Protein kinase domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

5 records

下载 cDNA FASTA

XR_009093262.1
TATGTTTCTTCGATTGAAATTTGCATACTTACCGAAGTGCAGTAACTGGGAGCCATTTATTAAAATAAAATAAAGTATGTAATGATGATGAGAAAGTTGTGTCTTAAGGAATATTGATAAAATCTAGTAGAAGAATATTAAGATATCACCATTTAACAGAAACACTCCCTCTTTCCGACGATCTGATTCTGAGCTGAAGGAAAGGAAACGTGACGAAAGAGAGATAGAATTGAAGTCCTCCGATAATGGCGAATCCCGAC...

XR_009093261.1
TGTTTCTTCGATTGAAATTTGCATACTTACCGAAGTGCAGTAACTGGGAGCCATTTATTAAAATAAAATAAAGTATGTAATGATGATGAGAAAGTTGTGTCTTAAGGAATATTGATAAAATCTAGTAGAAGAATATTAAGATATCACCATTTAACAGAAACACTCCCTCTTTCCGACGATCTGATTCTGAGCTGAAGGAAAGGAAACGTGACGAAAGAGAGATAGAATTGAAGTCCTCCGATAATGGCGGTGCGTCGGGT...

CDS

3 records

下载 CDS FASTA

LOC130997943
ATGGAAATGCCTGGAAGGCGATCTAATTACGCTCTGTTAAGCCAGAATCCCGACGAACCGTTCTACCCCCAGCCGCCGCCAAAGCAGCCGAAAGTCTCCGTCGCTCCGGTGGCTCAGCAGCCTCTTTACTACGAATCTCACTCCGGCGAGAAGAATAAGTTGAAGTCCGGCAGAGCAGGAGCCTTTGACGCGATTGATCAAAGAATGATTCAGGGGCAGCCGCAGCCGCAGCAGAGCCGGATTGCAACGGCGCCGTTTTT...

Protein

3 records

下载 Protein FASTA

XP_057779363.1
MEMPGRRSNYALLSQNPDEPFYPQPPPKQPKVSVAPVAQQPLYYESHSGEKNKLKSGRAGAFDAIDQRMIQGQPQPQQSRIATAPFLGSFGLQRQSSESSFGESSLSGDYYVPSLSNPDVGISNLSDGVGEFRAKATEVSFSGGDGSSSSKSWALQTEESYQLQLALALRLSSEATCADDPNFLDPVPDEAACVAASSPASAEAISHRYWINGCLSYFDRIPDGFYMIHGMDPYVWTVCSDHQESGRIPSFESLRTVDPA...

XP_057779364.1
MEMPGRRSNYALLSQNPDEPFYPQPPPKQPKVSVAPVAQQPLYYESHSGEKNKLKSGRAGAFDAIDQRMIQGQPQPQQSRIATAPFLGSFGLQRQSSESSFGESSLSGDYYVPSLSNPDVGISNLSDGVGEFRAKATEVSFSGGDGSSSSKSWALQTEESYQLQLALALRLSSEATCADDPNFLDPVPDEAACVAASSPASAEAISHRYWINGCLSYFDRIPDGFYMIHGMDPYVWTVCSDHQESGRIPSFESLRTVDPA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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