Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G004244`

染色体: Chr08 坐标: 51900423-51903986 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G004244`
名称	SmilChr08G004244
描述	3-methyl-2-oxobutanoate hydroxymethyltransferase 1, mitochondrial-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	51900423 - 51903986 / `+`

ID 对照

NCBI Gene ID	`LOC130998974`
GeneID	`130998974`
locus_tag	`-`
NCBI Name	`LOC130998974`
原始查询	`LOC130998974`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	3-methyl-2-oxobutanoate hydroxymethyltransferase 1, mitochondrial-like
产物	3-methyl-2-oxobutanoate hydroxymethyltransferase 1%2C mitochondrial-like
Arabidopsis	`AT2G46110` (KPHMT1) ketopantoate hydroxymethyltransferase 1 [Source:NCBI gene (formerly Entrezgene);Acc:819219] identity=82; qcov=0.989; evalue=0; confidence=high
Rice	`Os01g0225500` (KPHMT2) - identity=71.7; qcov=0.817; evalue=5.14e-149; confidence=high
GO	GO:0000287 (magnesium ion binding); GO:0003864 (3-methyl-2-oxobutanoate hydroxymethyltransferase activity); GO:0005739 (mitochondrion); GO:0015940 (pantothenate biosynthetic process)
KEGG	smil00770 (Pantothenate and CoA biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage))
Pfam	PF02548 (Pantoate_transf)
InterPro	-
eggNOG	-
NR	GeneID:130998974

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057780407.1`
2	Mitochondrion matrix	线粒体基质	1.00000	`XP_057780407.1`
3	Nucleus	细胞核	0.00000	`XP_057780407.1`
4	Chromosome	染色体	0.00000	`XP_057780407.1`
5	Centromere	着丝粒	0.00000	`XP_057780407.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:51900577`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C80
`Chr8:51900606`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr8:51900634`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B16
`Chr8:51900663`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C39
`Chr8:51901567`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B44,C70
`Chr8:51901574`	`GC`	`G`	1bp_deletion	frameshift_variant	175	A1,A10,A11,A13,A14,A15,A18,A19,A21,A22,A23,A24,A25,A3,A4,A5,A6,A7,A8,A9,B10,B100,B101,B103,B106,B11,B112,B113,B114,B117,B119,B12,B121,B122,B123,B124,B125,B126,B127,B128,B129,B13,B131,B132,B134,B135,B136,B137,B138,B139,B14,B15,B16,B17,B18,B2,B20,B21,B23,B25,B27,B28,B29,B30,B31,B32,B34,B35,B37,B38,B39,B41,B42,B43,B46,B48,B49,B5,B50,B51,B53,B55,B57,B59,B60,B61,B62,B63,B65,B67,B68,B69,B7,B71,B72,B73,B74,B75,B77,B78,B79,B80,B81,B82,B83,B84,B85,B88,B89,B9,B90,B91,B92,B94,B95,B96,B97,B98,B99,C1,C11,C13,C16,C17,C19,C23,C24,C25,C29,C3,C31,C33,C36,C37,C39,C41,C43,C45,C46,C48,C5,C51,C52,C54,C55,C57,C58,C59,C60,C61,C62,C64,C65,C66,C69,C71,C73,C74,C75,C78,C79,C8,C80,C81,C82,C83,C84,C86,C87,C9,D10,D4,D5,D6,D8
`Chr8:51901585`	`AGT`	`A`	2bp_deletion	frameshift_variant	107	A11,A13,A16,A18,A19,A2,A20,A21,A4,A6,A7,A9,B10,B101,B106,B107,B108,B112,B113,B117,B120,B121,B122,B125,B126,B129,B13,B130,B132,B14,B15,B16,B17,B18,B19,B2,B29,B3,B30,B32,B36,B38,B39,B40,B43,B45,B46,B49,B5,B56,B57,B6,B60,B66,B67,B68,B7,B70,B80,B84,B87,B88,B90,B94,B96,B97,B98,C1,C10,C14,C16,C18,C20,C21,C23,C25,C26,C27,C29,C30,C37,C39,C4,C40,C41,C42,C47,C49,C5,C56,C59,C6,C60,C62,C63,C67,C72,C8,C80,C83,C86,D11,D5,D6,D7,D8,D9
`Chr8:51901594`	`TG`	`T`	1bp_deletion	frameshift_variant	1	B44
`Chr8:51901594`	`TG`	`T`	1bp_deletion	CDS_variant	1	B44
`Chr8:51901610`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B96
`Chr8:51901629`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B132,B135,B46,C46,C79
`Chr8:51901855`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A25,B115,B77,C38,D2

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057780407.1

355 aa

178

355

Pantoate_transf

PF02548 Pantoate_transf 48-311 aa

XP_057780408.1

355 aa

178

355

Pantoate_transf

PF02548 Pantoate_transf 48-311 aa

XP_057780409.1

355 aa

178

355

Pantoate_transf

PF02548 Pantoate_transf 48-311 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057780407.1`	Pfam	`PF02548`	Pantoate_transf	Family	48	311	2e-104	349.3	Ketopantoate hydroxymethyltransferase
`XP_057780408.1`	Pfam	`PF02548`	Pantoate_transf	Family	48	311	2e-104	349.3	Ketopantoate hydroxymethyltransferase
`XP_057780409.1`	Pfam	`PF02548`	Pantoate_transf	Family	48	311	2e-104	349.3	Ketopantoate hydroxymethyltransferase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057924426.1
TCCGTTGAATGGAATTTAACAAAACAATATAAAAACTTGGTACATTCCTACTCCTCCAACTACCCATCATTTTCCTTTCCCGGCGGCGCCGCCACCCTCCACCGCTGCCACCAAAATGTCTTCTTCACTCTTCAAAACCCTCCGCCGCACCTCCGTCACCAACCGCCTCAGTTCTGCGAAGTCCATTTTCCGGTGGCTGAGTAACGTGCCGGAAAACACCGTCTACGGCGGCCCGAAGCCGCAGAACCCTAACCAGCGCG...

XM_057924425.1
TCCGTTGAATGGAATTTAACAAAACAATATAAAAACTTGGTACATTCCTACTCCTCCAACTACCCATCATTTTCCTTTCCCGGCGGCGCCGCCACCCTCCACCGCTGCCACCAAAATGTCTTCTTCACTCTTCAAAACCCTCCGCCGCACCTCCGTCACCAACCGCCTCAGTTCTGCGAAGTCCATTTTCCGGTGGCTGAGTAACGTGCCGGAAAACACCGTCTACGGCGGCCCGAAGCCGCAGAACCCTAACCAGCGCG...

CDS

3 records

下载 CDS FASTA

LOC130998974
ATGTCTTCTTCACTCTTCAAAACCCTCCGCCGCACCTCCGTCACCAACCGCCTCAGTTCTGCGAAGTCCATTTTCCGGTGGCTGAGTAACGTGCCGGAAAACACCGTCTACGGCGGCCCGAAGCCGCAGAACCCTAACCAGCGCGTCACGCTCACTAACATCCGCCAGAAGCACAGGAGGCGCGAGCCCATAACCATGGTCACGGCGTACGACTACCCGTCGGCGGTGCATCTGGACACCGCCGGCATCGACATTTGCTT...

Protein

3 records

下载 Protein FASTA

XP_057780407.1
MSSSLFKTLRRTSVTNRLSSAKSIFRWLSNVPENTVYGGPKPQNPNQRVTLTNIRQKHRRREPITMVTAYDYPSAVHLDTAGIDICLVGDSAAMVVHGHDTTLPITLDEMLVHCRAVARGARRPLLVGDLPFGTYESSTQQAVDTAVRVLKEGGMDAIKLEGGAPSRITAAKGIVEAGIAVIGHVGLTPQAISVLGGFRPQGRNIDSAVKVVETSMALQESGCFAVVLECVPPPVAAAATSALQIPTIGIGAGPFCSGQV...

XP_057780408.1
MSSSLFKTLRRTSVTNRLSSAKSIFRWLSNVPENTVYGGPKPQNPNQRVTLTNIRQKHRRREPITMVTAYDYPSAVHLDTAGIDICLVGDSAAMVVHGHDTTLPITLDEMLVHCRAVARGARRPLLVGDLPFGTYESSTQQAVDTAVRVLKEGGMDAIKLEGGAPSRITAAKGIVEAGIAVIGHVGLTPQAISVLGGFRPQGRNIDSAVKVVETSMALQESGCFAVVLECVPPPVAAAATSALQIPTIGIGAGPFCSGQV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器