Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G000027`

染色体: Chr08 坐标: 179349-184205 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G000027`
名称	SmilChr08G000027
描述	copper-transporting ATPase HMA4-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	179349 - 184205 / `-`

ID 对照

NCBI Gene ID	`LOC130999652`
GeneID	`130999652`
locus_tag	`-`
NCBI Name	`LOC130999652`
原始查询	`LOC130999652`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	copper-transporting ATPase HMA4-like
产物	copper-transporting ATPase HMA4-like
Arabidopsis	`AT1G63440` (HMA5) heavy metal atpase 5 [Source:NCBI gene (formerly Entrezgene);Acc:842650] identity=56.5; qcov=0.968; evalue=0; confidence=high
Rice	`Os02g0196600` (HMA4) - identity=68.5; qcov=1; evalue=0; confidence=high
GO	GO:0005507 (copper ion binding); GO:0005524 (ATP binding); GO:0006812 (monoatomic cation transport); GO:0016020 (membrane); GO:0016887 (ATP hydrolysis activity); GO:0019829 (ATPase-coupled monoatomic cation transmembrane transporter activity)
KEGG	smil04016 (MAPK signaling pathway - plant - Salvia miltiorrhiza (redroot sage))
Pfam	PF00122 (E1-E2_ATPase); PF00403 (HMA); PF00702 (Hydrolase)
InterPro	-
eggNOG	-
NR	GeneID:130999652

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Vacuole	液泡	0.80000	`XP_057781231.1`
2	Vacuole membrane	液泡膜	0.80000	`XP_057781231.1`
3	Endoplasmic reticulum	内质网	0.40000	`XP_057781231.1`
4	Endoplasmic reticulum membrane	内质网膜	0.40000	`XP_057781231.1`
5	Nucleus	细胞核	0.00000	`XP_057781231.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:179602`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B38,B39,B44
`Chr8:179643`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B100,B127,C41,D11
`Chr8:179670`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B105,B119,B2,B47,C51
`Chr8:179716`	`AT`	`A`	1bp_deletion	frameshift_variant	2	B32,D11
`Chr8:179716`	`AT`	`A`	1bp_deletion	CDS_variant	2	B32,D11
`Chr8:179724`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B32,D11
`Chr8:179727`	`AGG`	`A`	2bp_deletion	frameshift_variant	2	B32,D11
`Chr8:179727`	`AGG`	`A`	2bp_deletion	CDS_variant	2	B32,D11
`Chr8:179743`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B19,B21
`Chr8:179779`	`GC`	`G`	1bp_deletion	frameshift_variant	10	A25,B114,B55,B7,B76,C15,C20,C39,C53,D8
`Chr8:179786`	`TG`	`T`	1bp_deletion	frameshift_variant	2	B32,D11
`Chr8:179786`	`TG`	`T`	1bp_deletion	CDS_variant	2	B32,D11

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057781231.1

960 aa

480

960

HMA

E1-E2_ATPase

Hydrolase

PF00403 HMA 32-93 aa PF00403 HMA 107-167 aa PF00403 HMA 197-241 aa PF00122 E1-E2_ATPase 431-519 aa PF00702 Hydrolase 628-853 aa

XP_057781232.1

960 aa

480

960

HMA

E1-E2_ATPase

Hydrolase

PF00403 HMA 32-93 aa PF00403 HMA 107-167 aa PF00403 HMA 197-241 aa PF00122 E1-E2_ATPase 431-519 aa PF00702 Hydrolase 628-853 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057781231.1`	Pfam	`PF00403`	HMA	Domain	32	93	3.5e-37	127.3	Heavy-metal-associated domain
`XP_057781231.1`	Pfam	`PF00403`	HMA	Domain	107	167	3.5e-37	127.3	Heavy-metal-associated domain
`XP_057781231.1`	Pfam	`PF00403`	HMA	Domain	197	241	3.5e-37	127.3	Heavy-metal-associated domain
`XP_057781231.1`	Pfam	`PF00122`	E1-E2_ATPase	Domain	431	519	1.6e-26	92.8	P-type ATPase actuator domain
`XP_057781231.1`	Pfam	`PF00702`	Hydrolase	Domain	628	853	2.2e-33	117.0	haloacid dehalogenase-like hydrolase
`XP_057781232.1`	Pfam	`PF00403`	HMA	Domain	32	93	3.5e-37	127.3	Heavy-metal-associated domain
`XP_057781232.1`	Pfam	`PF00403`	HMA	Domain	107	167	3.5e-37	127.3	Heavy-metal-associated domain
`XP_057781232.1`	Pfam	`PF00403`	HMA	Domain	197	241	3.5e-37	127.3	Heavy-metal-associated domain
`XP_057781232.1`	Pfam	`PF00122`	E1-E2_ATPase	Domain	431	519	1.6e-26	92.8	P-type ATPase actuator domain
`XP_057781232.1`	Pfam	`PF00702`	Hydrolase	Domain	628	853	2.2e-33	117.0	haloacid dehalogenase-like hydrolase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057925248.1
GCTTAATATTATCTGACAAAGCGAAGCCAAACACAACCTAAACCTTTTTTAAAATTGAAATTTGCCACCAGTTTTGCTACTGGCGCGGCGCTTCCAGTTCTGATCATCACGAGAGGTCGTTGCTTTCGGAGCAGATAAATCATGGATATAAACGGGAAACATGATCTGAGTTCGCCGCTTTTACAACATCGAGATGATGTCGTCGTTGCTATCACCGAGAAGACGAGGACGTTAGTATTCAAAGTTGTGGGGATAACATG...

XM_057925249.1
AAACACAACCTAAACCTTTTTTAAAATTGAAATTTGCCACCAGTTTTGCTACTGGCGCGGCGCTTCCAGTTCTGGTAATTGACGGCGTCGCGGCCTCTCTCGGCGTTGCCGCCCCTCCAGAATTTCAATTTTTGTTTCGATATTTAGCCTTTCACCGTTCTAATTGAGTGATAGGAATATATTCCTAGCCTTTCGCTCGGTGGAATTCAGCTGACAATATTCTCTGCGTTGTTTGAATTGGGCTTTGCAGATCATCACGA...

CDS

2 records

下载 CDS FASTA

LOC130999652
ATGGATATAAACGGGAAACATGATCTGAGTTCGCCGCTTTTACAACATCGAGATGATGTCGTCGTTGCTATCACCGAGAAGACGAGGACGTTAGTATTCAAAGTTGTGGGGATAACATGCGCGTCTTGTGTGGCTTCGATTGAATCTGCGCTTGGAGGAATCGACGGCGTGCAGAGCGTGATGGTTTCCGTGCTTCAAGGTCGAGCTGTGGTGAAGTATGTGCCTGAAATTATCGCTGCAAAAAGGATAAAGGAAGCAGT...

Protein

2 records

下载 Protein FASTA

XP_057781231.1
MDINGKHDLSSPLLQHRDDVVVAITEKTRTLVFKVVGITCASCVASIESALGGIDGVQSVMVSVLQGRAVVKYVPEIIAAKRIKEAVEDTGFEVVDFPEQDNAMCRVRIKGMACTSCSESVERALRMVDGIKKAVVGLALGEAKIHFDPNITDTNRIIQAIEEDAGFGAELISSGNDLSKLYLKLGGITSPDDFTIIQKSLESLEGVNHVEVDPEQHTAIISYEPNVIGPRSLIQCIQEAGDGSNTYQATLYTPPRGGET...

XP_057781232.1
MDINGKHDLSSPLLQHRDDVVVAITEKTRTLVFKVVGITCASCVASIESALGGIDGVQSVMVSVLQGRAVVKYVPEIIAAKRIKEAVEDTGFEVVDFPEQDNAMCRVRIKGMACTSCSESVERALRMVDGIKKAVVGLALGEAKIHFDPNITDTNRIIQAIEEDAGFGAELISSGNDLSKLYLKLGGITSPDDFTIIQKSLESLEGVNHVEVDPEQHTAIISYEPNVIGPRSLIQCIQEAGDGSNTYQATLYTPPRGGET...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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