Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G004175`

染色体: Chr01 坐标: 60216834-60220138 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G004175`
名称	SmilChr01G004175
描述	MDIS1-interacting receptor like kinase 1-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	60216834 - 60220138 / `+`

ID 对照

NCBI Gene ID	`LOC131000007`
GeneID	`131000007`
locus_tag	`-`
NCBI Name	`LOC131000007`
原始查询	`LOC131000007`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	MDIS1-interacting receptor like kinase 1-like
产物	MDIS1-interacting receptor like kinase 1-like
Arabidopsis	`AT4G28650` (AT4G28650) Leucine-rich repeat transmembrane protein kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:828983] identity=62; qcov=1.03; evalue=0; confidence=high
Rice	`Os02g0111800` (OsCLVATA) - identity=57.7; qcov=0.994; evalue=0; confidence=high
GO	GO:0004672 (protein kinase activity); GO:0005515 (protein binding); GO:0005524 (ATP binding); GO:0006468 (protein phosphorylation)
KEGG	-
Pfam	PF00069 (Pkinase); PF00560 (LRR_1); PF07714 (PK_Tyr_Ser-Thr); PF08263 (LRRNT_2); PF13855 (LRR_8)
InterPro	-
eggNOG	-
NR	GeneID:131000007

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057781716.1`
2	Nucleus	细胞核	0.00000	`XP_057781716.1`
3	Chromosome	染色体	0.00000	`XP_057781716.1`
4	Centromere	着丝粒	0.00000	`XP_057781716.1`
5	Chromatin	染色质	0.00000	`XP_057781716.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:60217065`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B7,C5
`Chr1:60217219`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B122
`Chr1:60217220`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A25,B79,C27,C49
`Chr1:60217238`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B117,B53
`Chr1:60217304`	`CCG`	`C`	2bp_deletion	frameshift_variant	65	A11,A15,A19,A2,B100,B104,B105,B107,B109,B110,B112,B115,B118,B119,B120,B122,B126,B127,B135,B17,B20,B26,B29,B3,B30,B33,B37,B44,B49,B55,B56,B59,B62,B64,B67,B69,B7,B74,B77,B78,B79,B86,B91,B95,C26,C29,C37,C41,C45,C46,C49,C5,C51,C53,C54,C67,C68,C77,C83,C85,C87,D2,D4,D5,D6
`Chr1:60217323`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B17
`Chr1:60217368`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B7,B93,C63,C67
`Chr1:60217398`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B118,B65,C42,C87
`Chr1:60217430`	`GCT`	`G`	2bp_deletion	frameshift_variant	81	A1,A16,A19,A2,A20,A21,A24,B100,B101,B103,B107,B109,B110,B113,B118,B119,B120,B123,B125,B126,B127,B128,B135,B137,B139,B14,B16,B2,B20,B25,B3,B30,B33,B37,B41,B42,B44,B5,B52,B58,B63,B64,B66,B67,B69,B71,B74,B8,B83,B86,B88,B89,B97,B98,C1,C12,C13,C17,C23,C24,C29,C3,C32,C35,C45,C47,C49,C5,C50,C52,C54,C55,C63,C64,C65,C82,C85,D1,D2,D5,D6
`Chr1:60217434`	`A`	`AGC`	2bp_insertion	frameshift_variant	81	A1,A16,A19,A2,A20,A21,A24,B100,B101,B103,B107,B109,B110,B113,B118,B119,B120,B123,B125,B126,B127,B128,B135,B137,B139,B14,B16,B2,B20,B25,B3,B30,B33,B37,B41,B42,B44,B5,B52,B58,B63,B64,B66,B67,B69,B71,B74,B8,B83,B86,B88,B89,B97,B98,C1,C12,C13,C17,C23,C24,C29,C3,C32,C35,C45,C47,C49,C5,C50,C52,C54,C55,C63,C64,C65,C82,C85,D1,D2,D5,D6
`Chr1:60217445`	`G`	`GC`	1bp_insertion	frameshift_variant	77	A1,A16,A19,A2,A20,A21,A24,B100,B101,B103,B107,B109,B110,B113,B119,B120,B123,B125,B126,B127,B128,B135,B137,B139,B14,B16,B2,B20,B3,B30,B33,B37,B41,B42,B44,B5,B52,B58,B63,B64,B66,B67,B69,B71,B74,B8,B83,B88,B89,B98,C1,C12,C13,C17,C23,C24,C29,C3,C32,C35,C45,C47,C49,C5,C50,C52,C54,C55,C63,C64,C65,C82,C85,D1,D2,D5,D6
`Chr1:60217503`	`CG`	`C`	1bp_deletion	frameshift_variant	15	B109,B119,B135,B16,B20,B5,B88,B89,B98,C45,C5,C64,C85,D1,D5

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057781716.1

983 aa

492

983

LRRNT_2

LRR_8

LRR_1

LRR_8

LRR_1

Pkinase

PK_Tyr_Ser-Thr

PF08263 LRRNT_2 24-60 aa PF13855 LRR_8 67-123 aa PF00560 LRR_1 89-111 aa PF00560 LRR_1 159-180 aa PF00560 LRR_1 182-203 aa PF00560 LRR_1 279-300 aa PF00560 LRR_1 326-347 aa PF00560 LRR_1 351-370 aa PF00560 LRR_1 374-396 aa PF00560 LRR_1 398-420 aa PF13855 LRR_8 398-457 aa PF00560 LRR_1 422-441 aa PF00560 LRR_1 495-516 aa PF00560 LRR_1 519-537 aa PF00560 LRR_1 543-563 aa PF00069 Pkinase 693-956 aa PF07714 PK_Tyr_Ser-Thr 693-957 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057781716.1`	Pfam	`PF08263`	LRRNT_2	Family	24	60	2.2e-08	34.9	Leucine rich repeat N-terminal domain
`XP_057781716.1`	Pfam	`PF13855`	LRR_8	Repeat	67	123	8.5e-49	163.9	Leucine rich repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	89	111	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	159	180	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	182	203	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	279	300	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	326	347	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	351	370	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	374	396	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	398	420	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF13855`	LRR_8	Repeat	398	457	8.5e-49	163.9	Leucine rich repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	422	441	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	495	516	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	519	537	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00560`	LRR_1	Repeat	543	563	1e-59	186.2	Leucine Rich Repeat
`XP_057781716.1`	Pfam	`PF00069`	Pkinase	Domain	693	956	9e-46	157.1	Protein kinase domain
`XP_057781716.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	693	957	1.9e-40	139.5	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057925733.1
TATAAACCGAGCTTCCTCCGCTACCCCACCAGCCCCGCCAAGAAACATGATGAAAAAGTGATCCCAAAACAAGAAACAAATCAACATGAAAAACAAGTTTCTCTTACTCTTTCTCTTCTTCTCTTGCCACTATATCTCCTCCTTCTCTGAGGTGGATGAAGCGTCGCTTCTTCTGTCGATCAAAGCAGCCCTCTTCGACCCACTGGATCATCTCGGAGACTGGAAATCGCCCGAAAACCACTGCAGATGGAGTGGAGTTG...

CDS

1 records

下载 CDS FASTA

LOC131000007
ATGAAAAACAAGTTTCTCTTACTCTTTCTCTTCTTCTCTTGCCACTATATCTCCTCCTTCTCTGAGGTGGATGAAGCGTCGCTTCTTCTGTCGATCAAAGCAGCCCTCTTCGACCCACTGGATCATCTCGGAGACTGGAAATCGCCCGAAAACCACTGCAGATGGAGTGGAGTTGGGTGCGGCCACAATGGCATGGTTGAGAATCTTCATCTTTCACACATGAATCTCTCTGGTAGGCTGCCTGATGCAATCCAGGGATT...

Protein

1 records

下载 Protein FASTA

XP_057781716.1
MKNKFLLLFLFFSCHYISSFSEVDEASLLLSIKAALFDPLDHLGDWKSPENHCRWSGVGCGHNGMVENLHLSHMNLSGRLPDAIQGLTSLKHLNLSCNEFASPLPNSFSNLTALESIDLSQNYFIDAFPGLAAGLVAVNASGNNFSGPLPDDLGNATLLESLDLRGNFFQGSIPRSYKNLGSLRFLGLSGNNLTGEIPAELGAMASLETMILGYNAFDGGIPADLGNLTNLKYLDIAIANLSGPIPPEMGRLKQLTTIFL...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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