当前解析结果
SmilChr08G000973| 统一基因 ID | SmilChr08G000973 |
|---|---|
| 名称 | SmilChr08G000973 |
| 描述 | cell division cycle protein 48 homolog |
| 染色体 / SeqID | Chr08 / NC_080394.1 |
| 坐标与链方向 | 7239215 - 7243948 / + |
| NCBI Gene ID | LOC131000533 |
|---|---|
| GeneID | 131000533 |
| locus_tag | - |
| NCBI 名称 | LOC131000533 |
| 原始查询 | LOC131000533 |
| 来源 | GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog |
|---|---|
| 描述 | cell division cycle protein 48 homolog |
| 产物 | cell division cycle protein 48 homolog |
| 拟南芥 | AT5G03340 (AtCDC48C)ATPase, AAA-type, CDC48 protein [Source:NCBI gene (formerly Entrezgene);Acc:831870] identity=91.49; qcov=1.0; evalue=0.0; confidence=high |
| 水稻 | Os03g0151800 (OsCDC48)- identity=90.75; qcov=0.978; evalue=0.0; confidence=high |
| GO | GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0005829 (cytosol); GO:0016887 (ATP hydrolysis activity); GO:0030433 (GO:0030433); GO:0030970 (retrograde protein transport, ER to cytosol); GO:0031593 (polyubiquitin modification-dependent protein binding); GO:0034098 (VCP-NPL4-UFD1 AAA ATPase complex); GO:0051228 (mitotic spindle disassembly); GO:0071712 (GO:0071712); GO:0097352 (autophagosome maturation) |
| KEGG | smil04141 (Protein processing in endoplasmic reticulum - Salvia miltiorrhiza (redroot sage)) |
| Pfam | PF00004 (AAA); PF02359 (CDC48_N); PF02933 (CDC48_2); PF07728 (AAA_5); PF17862 (AAA_lid_3) |
| InterPro | - |
| eggNOG | - |
| NR | GeneID:131000533 |
预测得分表示模型支持程度，不能作为定位概率；所有候选均需实验验证。
当前结果已使用全部46,325条核基因组蛋白的完整原生特征重算。逐条核验39×39×7 PROFEAT、1280维ESM2、整条序列及五组模型的定位判定；当前模型、阈值文件和执行种子有记录。历史缓存及历史执行版本仍未确认。结果为计算候选，预测得分表示模型支持程度，不是校准概率，也不代表实验确认或已建立的预测准确率。模型含部分动物相关标签，应谨慎解读其在植物中的适用性。 四舍五入后概率与阈值相等的481条记录已按未舍入模型值再次复核，原始投票全部一致。
| 排序 | 定位位置 | 预测得分 | 蛋白 ID |
|---|---|---|---|
| 1 | 细胞质基质 | 1.00000 | XP_057782482.1 |
| 2 | 细胞质 | 1.00000 | XP_057782484.1 |
| 3 | 细胞核 | 0.80000 | XP_057782482.1 |
下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。
| 位置 | 参考等位基因 | 变异等位基因 | 类型 | 影响 | 携带材料数 | 材料 |
|---|---|---|---|---|---|---|
Chr8:7239373 |
C |
T |
EMS_canonical_SNV | CDS_variant | 5 | B111,B8,C27,C57,C84 |
Chr8:7239560 |
G |
A |
EMS_canonical_SNV | CDS_variant | 3 | A11,A3,C58 |
Chr8:7240739 |
T |
TA |
1bp_insertion | frameshift_variant | 1 | C77 |
Chr8:7240739 |
T |
TA |
1bp_insertion | CDS_variant | 1 | C77 |
Chr8:7240741 |
G |
A |
EMS_canonical_SNV | CDS_variant | 2 | B113,C20 |
Chr8:7240815 |
G |
A |
EMS_canonical_SNV | CDS_variant | 1 | B108 |
Chr8:7240826 |
C |
T |
EMS_canonical_SNV | CDS_variant | 5 | B111,B8,C27,C57,C84 |
Chr8:7240860 |
C |
T |
EMS_canonical_SNV | stop_gained | 17 | A14,A7,B105,B109,B11,B114,B127,B132,B139,B34,B47,B65,B72,C30,C49,C57,D6 |
Chr8:7240883 |
G |
A |
EMS_canonical_SNV | CDS_variant | 5 | B124,B53,B62,C74,C80 |
Chr8:7240893 |
C |
T |
EMS_canonical_SNV | CDS_variant | 1 | B35 |
Chr8:7240996 |
A |
AG |
1bp_insertion | frameshift_variant | 2 | A8,B27 |
Chr8:7240996 |
A |
AG |
1bp_insertion | CDS_variant | 2 | A8,B27 |
结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。
XP_057782482.1PF02359
CDC48_N 30-111 aa
PF02933
CDC48_2 131-195 aa
PF07728
AAA_5 245-363 aa
PF00004
AAA 245-374 aa
PF17862
AAA_lid_3 397-438 aa
PF00004
AAA 518-651 aa
PF17862
AAA_lid_3 673-712 aa
XP_057782484.1PF02933
CDC48_2 43-107 aa
PF07728
AAA_5 157-275 aa
PF00004
AAA 157-286 aa
PF17862
AAA_lid_3 309-350 aa
PF00004
AAA 430-563 aa
PF17862
AAA_lid_3 585-624 aa
| 蛋白 ID | 来源 | 结构域编号 | 结构域名称 | 类型 | 起始 aa | 终止 aa | E-value | 得分 | 说明 |
|---|---|---|---|---|---|---|---|---|---|
XP_057782482.1 |
Pfam | PF02359 |
CDC48_N | Domain | 30 | 111 | 3.4e-23 | 82.4 | Cell division protein 48 (CDC48), N-terminal domain |
XP_057782482.1 |
Pfam | PF02933 |
CDC48_2 | Domain | 131 | 195 | 1.5e-11 | 44.4 | Cell division protein 48 (CDC48), domain 2 |
XP_057782482.1 |
Pfam | PF07728 |
AAA_5 | Domain | 245 | 363 | 2e-10 | 41.5 | AAA domain (dynein-related subfamily) |
XP_057782482.1 |
Pfam | PF00004 |
AAA | Domain | 245 | 374 | 3.7e-97 | 322.5 | ATPase family associated with various cellular activities (AAA) |
XP_057782482.1 |
Pfam | PF17862 |
AAA_lid_3 | Domain | 397 | 438 | 4.9e-31 | 106.6 | AAA+ lid domain |
XP_057782482.1 |
Pfam | PF00004 |
AAA | Domain | 518 | 651 | 3.7e-97 | 322.5 | ATPase family associated with various cellular activities (AAA) |
XP_057782482.1 |
Pfam | PF17862 |
AAA_lid_3 | Domain | 673 | 712 | 4.9e-31 | 106.6 | AAA+ lid domain |
XP_057782484.1 |
Pfam | PF02933 |
CDC48_2 | Domain | 43 | 107 | 1.4e-11 | 44.5 | Cell division protein 48 (CDC48), domain 2 |
XP_057782484.1 |
Pfam | PF07728 |
AAA_5 | Domain | 157 | 275 | 1.4e-10 | 42.0 | AAA domain (dynein-related subfamily) |
XP_057782484.1 |
Pfam | PF00004 |
AAA | Domain | 157 | 286 | 2.6e-97 | 323.0 | ATPase family associated with various cellular activities (AAA) |
XP_057782484.1 |
Pfam | PF17862 |
AAA_lid_3 | Domain | 309 | 350 | 3.6e-31 | 107.0 | AAA+ lid domain |
XP_057782484.1 |
Pfam | PF00004 |
AAA | Domain | 430 | 563 | 2.6e-97 | 323.0 | ATPase family associated with various cellular activities (AAA) |
XP_057782484.1 |
Pfam | PF17862 |
AAA_lid_3 | Domain | 585 | 624 | 3.6e-31 | 107.0 | AAA+ lid domain |
每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。
2 records
下载 cDNA FASTA2 records
下载 CDS FASTA2 records
下载 Protein FASTAupstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。