Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G001044`

染色体: Chr08 坐标: 7976756-7979113 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G001044`
名称	SmilChr08G001044
描述	cinnamoyl-CoA reductase CAD2-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	7976756 - 7979113 / `+`

ID 对照

NCBI Gene ID	`LOC131000585`
GeneID	`131000585`
locus_tag	`-`
NCBI Name	`LOC131000585`
原始查询	`LOC131000585`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	cinnamoyl-CoA reductase CAD2-like
产物	cinnamoyl-CoA reductase CAD2-like
Arabidopsis	`AT5G58490` (AT5G58490) NAD(P)-binding Rossmann-fold superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:835962] identity=62.8; qcov=0.916; evalue=3.58e-125; confidence=high
Rice	`Os03g0818200` (OsCCR22) - identity=56.2; qcov=0.89; evalue=1.1e-91; confidence=high
GO	GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
KEGG	-
Pfam	PF01073 (3Beta_HSD); PF01370 (Epimerase); PF02719 (Polysacc_synt_2); PF05368 (NmrA); PF07993 (NAD_binding_4); PF08659 (KR); PF13460 (NAD_binding_10); PF16363 (GDP_Man_Dehyd)
InterPro	-
eggNOG	-
NR	GeneID:131000585

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057782573.1`
2	Cytoplasm	细胞质	0.80000	`XP_057782573.1`
3	Nucleus	细胞核	0.00000	`XP_057782573.1`
4	Chromosome	染色体	0.00000	`XP_057782573.1`
5	Centromere	着丝粒	0.00000	`XP_057782573.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:7976850`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C60
`Chr8:7977031`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B25,B68,B97
`Chr8:7977051`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr8:7977545`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B136
`Chr8:7978102`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A23,B107,B110
`Chr8:7978105`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A24
`Chr8:7978544`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C78
`Chr8:7978876`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A10,B119,B26,B85

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057782573.1

348 aa

174

348

NmrA

Epimerase

NAD_binding_4

3Beta_HSD

NAD_binding_10

GDP_Man_Dehyd

Polysacc_synt_2

PF05368 NmrA 9-130 aa PF08659 KR 10-164 aa PF01370 Epimerase 10-270 aa PF07993 NAD_binding_4 12-233 aa PF01073 3Beta_HSD 12-267 aa PF13460 NAD_binding_10 71-167 aa PF16363 GDP_Man_Dehyd 73-222 aa PF02719 Polysacc_synt_2 86-163 aa

XP_057782574.1

322 aa

161

322

NmrA

Polysacc_synt_2

Epimerase

GDP_Man_Dehyd

NAD_binding_4

3Beta_HSD

NAD_binding_10

PF05368 NmrA 9-104 aa PF02719 Polysacc_synt_2 10-137 aa PF08659 KR 10-138 aa PF01370 Epimerase 10-244 aa PF16363 GDP_Man_Dehyd 12-197 aa PF07993 NAD_binding_4 12-207 aa PF01073 3Beta_HSD 12-241 aa PF13460 NAD_binding_10 14-141 aa

XP_057782575.1

308 aa

154

308

NmrA

Polysacc_synt_2

Epimerase

GDP_Man_Dehyd

NAD_binding_4

3Beta_HSD

NAD_binding_10

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057782573.1`	Pfam	`PF05368`	NmrA	Family	9	130	2.1e-09	38.1	NmrA-like family
`XP_057782573.1`	Pfam	`PF08659`	KR	Family	10	164	1.3e-05	26.0	KR domain
`XP_057782573.1`	Pfam	`PF01370`	Epimerase	Family	10	270	1.4e-26	94.1	NAD dependent epimerase/dehydratase family
`XP_057782573.1`	Pfam	`PF07993`	NAD_binding_4	Family	12	233	2.9e-11	43.8	Male sterility protein
`XP_057782573.1`	Pfam	`PF01073`	3Beta_HSD	Family	12	267	5.8e-18	65.6	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057782573.1`	Pfam	`PF13460`	NAD_binding_10	Domain	71	167	9.9e-13	49.1	NAD(P)H-binding
`XP_057782573.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	73	222	1.3e-14	55.2	GDP-mannose 4,6 dehydratase
`XP_057782573.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	86	163	2.3e-06	27.7	Polysaccharide biosynthesis protein
`XP_057782574.1`	Pfam	`PF05368`	NmrA	Family	9	104	1.5e-11	45.1	NmrA-like family
`XP_057782574.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	10	137	2.3e-08	34.3	Polysaccharide biosynthesis protein
`XP_057782574.1`	Pfam	`PF08659`	KR	Family	10	138	1.6e-07	32.1	KR domain
`XP_057782574.1`	Pfam	`PF01370`	Epimerase	Family	10	244	3.6e-29	102.6	NAD dependent epimerase/dehydratase family
`XP_057782574.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	12	197	2.9e-18	67.1	GDP-mannose 4,6 dehydratase
`XP_057782574.1`	Pfam	`PF07993`	NAD_binding_4	Family	12	207	1.2e-11	44.9	Male sterility protein
`XP_057782574.1`	Pfam	`PF01073`	3Beta_HSD	Family	12	241	4.4e-21	75.8	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057782574.1`	Pfam	`PF13460`	NAD_binding_10	Domain	14	141	3e-14	54.0	NAD(P)H-binding
`XP_057782575.1`	Pfam	`PF05368`	NmrA	Family	9	104	1.5e-11	45.2	NmrA-like family
`XP_057782575.1`	Pfam	`PF02719`	Polysacc_synt_2	Family	10	137	2.1e-08	34.4	Polysaccharide biosynthesis protein
`XP_057782575.1`	Pfam	`PF08659`	KR	Family	10	138	1.5e-07	32.2	KR domain
`XP_057782575.1`	Pfam	`PF01370`	Epimerase	Family	10	244	3.1e-29	102.8	NAD dependent epimerase/dehydratase family
`XP_057782575.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	12	197	2.6e-18	67.3	GDP-mannose 4,6 dehydratase
`XP_057782575.1`	Pfam	`PF07993`	NAD_binding_4	Family	12	207	1.1e-11	45.1	Male sterility protein
`XP_057782575.1`	Pfam	`PF01073`	3Beta_HSD	Family	12	241	3.7e-21	76.1	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057782575.1`	Pfam	`PF13460`	NAD_binding_10	Domain	14	141	2.5e-14	54.3	NAD(P)H-binding

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057926591.1
AAAAAAAAACACGTTCTCCGCTAAGACACTCCCACATGGTGATGAGCAAGGAAGGAGAAGTTGTCTGCGTCACCGGCGCCAGCGGCTTCATCGGCTCTTGGCTCGTCCACTTTCTCCTCCACCGCGGCTACGCCGTCCGAGCCACTGTAAAAAATCTAGGAGATGAGAGAGAAACGAAGCACTTGGAAGCCATGGAAGGAGCTGATTCCCGCCTTCGCCTCTTCCAGATTGATCTGCTTGATTATGACTCCATTGTTGCC...

XM_057926592.1
AAAAAAAAACACGTTCTCCGCTAAGACACTCCCACATGGTGATGAGCAAGGAAGGAGAAGTTGTCTGCGTCACCGGCGCCAGCGGCTTCATCGGCTCTTGGCTCGTCCACTTTCTCCTCCACCGCGGCTACGCCGTCCGAGCCACTGTAAAAAATCTAGGAGATGAGAGAGAAACGAAGCACTTGGAAGCCATGGAAGGAGCTGATTCCCGCCTTCGCCTCTTCCAGATTGATCTGCTTGATTATGACTCCATTGTTGCC...

CDS

3 records

下载 CDS FASTA

LOC131000585
ATGGTGATGAGCAAGGAAGGAGAAGTTGTCTGCGTCACCGGCGCCAGCGGCTTCATCGGCTCTTGGCTCGTCCACTTTCTCCTCCACCGCGGCTACGCCGTCCGAGCCACTGTAAAAAATCTAGGTTCTGCTCCTCTCCATGTACCACCACTCGTTCAGAGTTCGCTGATACTCGATCTTTTTGCTAACTGTGAATTATTAGGAGATGAGAGAGAAACGAAGCACTTGGAAGCCATGGAAGGAGCTGATTCCCGCCTTCG...

LOC131000585
ATGGTGATGAGCAAGGAAGGAGAAGTTGTCTGCGTCACCGGCGCCAGCGGCTTCATCGGCTCTTGGCTCGTCCACTTTCTCCTCCACCGCGGCTACGCCGTCCGAGCCACTGTAAAAAATCTAGGAGATGAGAGAGAAACGAAGCACTTGGAAGCCATGGAAGGAGCTGATTCCCGCCTTCGCCTCTTCCAGATTGATCTGCTTGATTATGACTCCATTGTTGCCGCAGTCAGCGGCGCCGCCGGCGTCTTCCACCTAGC...

Protein

3 records

下载 Protein FASTA

XP_057782573.1
MVMSKEGEVVCVTGASGFIGSWLVHFLLHRGYAVRATVKNLGSAPLHVPPLVQSSLILDLFANCELLGDERETKHLEAMEGADSRLRLFQIDLLDYDSIVAAVSGAAGVFHLASPCIIDQIEDPQAELLDPAIKGTINVLKAAKNHNVRRVVVTSSISAMIPSSNSLADAGEGCWIDEDYCRQNGFLYSVSKALAEKAAWQFAEENGVDVVVLNPGVVAGPILTPAINTSMTLILHVLQGKDFPEELFEALVHVKDVALA...

XP_057782574.1
MVMSKEGEVVCVTGASGFIGSWLVHFLLHRGYAVRATVKNLGDERETKHLEAMEGADSRLRLFQIDLLDYDSIVAAVSGAAGVFHLASPCIIDQIEDPQAELLDPAIKGTINVLKAAKNHNVRRVVVTSSISAMIPSSNSLADAGEGCWIDEDYCRQNGFLYSVSKALAEKAAWQFAEENGVDVVVLNPGVVAGPILTPAINTSMTLILHVLQGKDFPEELFEALVHVKDVALAHILLYENTSAAGRHLCVESLSCYDDF...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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