Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G001369`

染色体: Chr08 坐标: 10907337-10912294 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G001369`
名称	SmilChr08G001369
描述	probable E3 ubiquitin-protein ligase ARI2
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	10907337 - 10912294 / `-`

ID 对照

NCBI Gene ID	`LOC131000836`
GeneID	`131000836`
locus_tag	`-`
NCBI Name	`LOC131000836`
原始查询	`LOC131000836`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	probable E3 ubiquitin-protein ligase ARI2
产物	probable E3 ubiquitin-protein ligase ARI2
Arabidopsis	`AT4G34370` (ARI1) RING/U-box superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:829587] identity=68.2; qcov=0.957; evalue=0; confidence=high
Rice	`Os03g0233500` - identity=64.4; qcov=0.95; evalue=0; confidence=high
GO	GO:0000151 (ubiquitin ligase complex); GO:0000209 (protein polyubiquitination); GO:0005737 (cytoplasm); GO:0006511 (ubiquitin-dependent protein catabolic process); GO:0008270 (zinc ion binding); GO:0031624 (ubiquitin conjugating enzyme binding); GO:0032436 (positive regulation of proteasomal ubiquitin-dependent protein catabolic process); GO:0061630 (ubiquitin protein ligase activity)
KEGG	-
Pfam	PF01485 (IBR); PF19422 (Ariadne); PF21235 (UBA_ARI1); PF22605 (IBR_2)
InterPro	-
eggNOG	-
NR	GeneID:131000836

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057782923.1`
2	Cytoplasm	细胞质	1.00000	`XP_057782924.1`
3	Cytosol	细胞质基质	0.20000	`XP_057782923.1`
4	Chromosome	染色体	0.00000	`XP_057782924.1`
5	Centromere	着丝粒	0.00000	`XP_057782924.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:10908750`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B55,C23,C73
`Chr8:10908827`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D8
`Chr8:10909003`	`G`	`A`	EMS_canonical_SNV	stop_gained	43	A13,A16,B1,B11,B110,B115,B122,B124,B126,B128,B13,B130,B139,B140,B15,B17,B26,B27,B33,B44,B50,B53,B62,B69,B73,B74,B80,B98,C18,C25,C27,C3,C35,C37,C39,C42,C45,C50,C53,C61,C8,C84,D7
`Chr8:10909087`	`G`	`A`	EMS_canonical_SNV	stop_gained	11	B113,B129,B49,B77,B88,C22,C7,C73,C77,C80,D7
`Chr8:10909124`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B35,B94,C34,C61
`Chr8:10909395`	`T`	`TA`	1bp_insertion	frameshift_variant	14	A13,B110,B126,B139,B140,B94,C23,C25,C35,C37,C39,C50,C61,C73
`Chr8:10909408`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B122,B13,B44,C18,C19
`Chr8:10909425`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C8
`Chr8:10909862`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B135
`Chr8:10909922`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B35,B94,C34,C61
`Chr8:10910110`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B35,B94,C34,C61
`Chr8:10910471`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B1

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057782923.1

596 aa

298

596

UBA_ARI1

IBR

IBR_2

Ariadne

PF21235 UBA_ARI1 58-97 aa PF01485 IBR 199-261 aa PF22605 IBR_2 281-323 aa PF19422 Ariadne 353-595 aa

XP_057782924.1

559 aa

280

559

UBA_ARI1

IBR

IBR_2

Ariadne

PF21235 UBA_ARI1 58-97 aa PF01485 IBR 199-261 aa PF22605 IBR_2 281-323 aa PF19422 Ariadne 353-553 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057782923.1`	Pfam	`PF21235`	UBA_ARI1	Domain	58	97	2.4e-08	34.3	E3 ubiquitin-protein ligase ARIH1, UBA-like domain
`XP_057782923.1`	Pfam	`PF01485`	IBR	Domain	199	261	5e-16	59.2	IBR domain, a half RING-finger domain
`XP_057782923.1`	Pfam	`PF22605`	IBR_2	Domain	281	323	1.4e-06	29.0	IBR domain
`XP_057782923.1`	Pfam	`PF19422`	Ariadne	Domain	353	595	2e-127	424.9	Ariadne domain
`XP_057782924.1`	Pfam	`PF21235`	UBA_ARI1	Domain	58	97	2.2e-08	34.4	E3 ubiquitin-protein ligase ARIH1, UBA-like domain
`XP_057782924.1`	Pfam	`PF01485`	IBR	Domain	199	261	4e-16	59.6	IBR domain, a half RING-finger domain
`XP_057782924.1`	Pfam	`PF22605`	IBR_2	Domain	281	323	1.3e-06	29.1	IBR domain
`XP_057782924.1`	Pfam	`PF19422`	Ariadne	Domain	353	553	7.8e-116	386.9	Ariadne domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057926940.1
TGGACTTTGGAGGACGCACTTTTCTCCAAACGACGACGTATGATCTACTCTACTACATACAGTACTCCCTTCCCTCACAGTAAACTAAAGGCGCAAAAACAAACCCTCCCTCCCCCCAAACTGGCAGCTTTCTCTCTCACCTTTTCAATCGCCGGCTGAATTTCGCCGGAAAATCATCTCGGCTCGGCCTGCTGATCCGATCACATAAGCGCAAGTTTCAAGCGGCTACTTTTGACCATTTATTTTATGAATATATACAT...

XM_057926941.1
ACGCACTTTTCTCCAAACGACGACGTATGATCTACTCTACTACATACAGTACTCCCTTCCCTCACAGTAAACTAAAGGCGCAAAAACAAACCCTCCCTCCCCCCAAACTGGCAGCTTTCTCTCTCACCTTTTCAATCGCCGGCTGAATTTCGCCGGAAAATCATCTCGGCTCGGCCTGCTGATCCGATCACATAAGCGCAAGTTTCAAGCGGCTACTTTTGACCATTTATTTTATGAATATATACATATTTTCTAGGGGA...

CDS

2 records

下载 CDS FASTA

LOC131000836
ATGGAGGACGATTATTACATGAGCGACAACAGCGAAGATAGAGATGAATCTTACTCGTCCGACAGAGAGGAGGAATCGCTCGACGGACTCGAGAATAAGGATCGCGATGCTCAATGGGTATCATCGAAAGCCCCTTCGTGCAAGGTGATTACAAGAGAGTCTCTGTTGGCTGCACAGACAGAAGATTTGGGGAGAGTGATGGACTTGTTCTCAGTGAGAGAACACCATGCCAGAACTCTACTCATTCATTACCGCTGGGA...

Protein

2 records

下载 Protein FASTA

XP_057782923.1
MEDDYYMSDNSEDRDESYSSDREEESLDGLENKDRDAQWVSSKAPSCKVITRESLLAAQTEDLGRVMDLFSVREHHARTLLIHYRWDVEKVIAVYVEKGKSGIFAEAGVTLAEFVDLDPEESTSTVMCYICMDDVPAKDVTLMDCGHCFCNNCWTEHFIVKINEGQSKRMRCMAHKCNAICDETIVRRLVSARHPDLAEKFDRFLLESYIEDNRMVKWCPSIPHCGNAIRVENDELCEVECSCGMQFCFSCVSEAHSPCS...

XP_057782924.1
MEDDYYMSDNSEDRDESYSSDREEESLDGLENKDRDAQWVSSKAPSCKVITRESLLAAQTEDLGRVMDLFSVREHHARTLLIHYRWDVEKVIAVYVEKGKSGIFAEAGVTLAEFVDLDPEESTSTVMCYICMDDVPAKDVTLMDCGHCFCNNCWTEHFIVKINEGQSKRMRCMAHKCNAICDETIVRRLVSARHPDLAEKFDRFLLESYIEDNRMVKWCPSIPHCGNAIRVENDELCEVECSCGMQFCFSCVSEAHSPCS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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