Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G001446`

染色体: Chr08 坐标: 11641458-11648094 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G001446`
名称	SmilChr08G001446
描述	squalene synthase 2-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	11641458 - 11648094 / `+`

ID 对照

NCBI Gene ID	`LOC131000996`
GeneID	`131000996`
locus_tag	`-`
NCBI Name	`LOC131000996`
原始查询	`LOC131000996`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	squalene synthase 2-like
产物	squalene synthase 2-like
Arabidopsis	`AT4G34640` (SQS1) squalene synthase 1 [Source:NCBI gene (formerly Entrezgene);Acc:829616] identity=76.1; qcov=0.99; evalue=0; confidence=high
Rice	`Os03g0805100` - identity=73.4; qcov=0.935; evalue=0; confidence=high
GO	GO:0004310 (GO:0004310); GO:0005789 (endoplasmic reticulum membrane); GO:0008610 (lipid biosynthetic process); GO:0045338 (farnesyl diphosphate metabolic process); GO:0051996 (squalene synthase [NAD(P)H] activity)
KEGG	smil00100 (Steroid biosynthesis - Salvia miltiorrhiza (redroot sage)); smil00909 (Sesquiterpenoid and triterpenoid biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF00494 (SQS_PSY)
InterPro	-
eggNOG	-
NR	GeneID:131000996

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	1.00000	`XP_057783132.1`
2	Endoplasmic reticulum membrane	内质网膜	1.00000	`XP_057783132.1`
3	Nucleus	细胞核	0.00000	`XP_057783132.1`
4	Chromosome	染色体	0.00000	`XP_057783132.1`
5	Centromere	着丝粒	0.00000	`XP_057783132.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:11641912`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B32,C62
`Chr8:11643646`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B139,B2
`Chr8:11643899`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A2
`Chr8:11644176`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B109
`Chr8:11644825`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C77
`Chr8:11646313`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B128,C30,C64,C66,D6
`Chr8:11647577`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	A2
`Chr8:11647577`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A2

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057783132.1

420 aa

210

420

SQS_PSY

PF00494 SQS_PSY 44-315 aa

XP_057783133.1

420 aa

210

420

SQS_PSY

PF00494 SQS_PSY 44-315 aa

XP_057783134.1

414 aa

207

414

SQS_PSY

PF00494 SQS_PSY 44-315 aa

XP_057783135.1

414 aa

207

414

SQS_PSY

PF00494 SQS_PSY 44-315 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057783132.1`	Pfam	`PF00494`	SQS_PSY	Domain	44	315	1.4e-53	183.0	Squalene/phytoene synthase
`XP_057783133.1`	Pfam	`PF00494`	SQS_PSY	Domain	44	315	1.4e-53	183.0	Squalene/phytoene synthase
`XP_057783134.1`	Pfam	`PF00494`	SQS_PSY	Domain	44	315	1.3e-53	183.1	Squalene/phytoene synthase
`XP_057783135.1`	Pfam	`PF00494`	SQS_PSY	Domain	44	315	1.3e-53	183.1	Squalene/phytoene synthase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057927150.1
GAAAAGAAATGGTAAACAGCATAACAACTTACTTTAGTCAAAGATTTCAGGCTCTTCAATTTTCCATCCAGCAAACCCCACACATATTTACACACACTACACGCACTAACTACTTCAACAGCACTCCTTTCTTTCAATCACTCCCCCATTAAATACATAAAGTCATCTTTGTATGCCCACATTTTCAGCAGCACGCACAAAATTCATCGTCGCAATTCGCGCTCGCTCTCCATTTTCAGAATATTCATAACTCTCGGAAT...

XM_057927151.1
AAAAGAAATGGTAAACAGCATAACAACTTACTTTAGTCAAAGATTTCAGGCTCTTCAATTTTCCATCCAGCAAACCCCACACATATTTACACACACTACACGCACTAACTACTTCAACAGCACTCCTTTCTTTCAATCACTCCCCCATTAAATACATAAAGTCATCTTTGTATGCCCACATTTTCAGCAGCACGCACAAAATTCATCGTCGCAATTCGCGCTCGCTCTCCATTTTCAGAATATTCATAACTCTCGGAATC...

CDS

4 records

下载 CDS FASTA

LOC131000996
ATGGTGAATTTGGGGGCGATTTTGAAGCATCCGGAAGATTTGTATCCGATGGTGAAACTGAAACTGGCGGCGCGACAGGCTGAGAAGCAGATACCGGCGGAGCCGCACTGGGCATTTTGTTATTCCATGCTTCATAAAGTATCTAGAAGTTTCGCTCTCGTTATTCAGCAGCTCGATACTGATCTTCGTGATGCTGTATGCATATTCTATTTAGTTCTGCGAGCGCTTGACACAGTTGAGGATGATACAAGCATAGCATC...

Protein

4 records

下载 Protein FASTA

XP_057783132.1
MVNLGAILKHPEDLYPMVKLKLAARQAEKQIPAEPHWAFCYSMLHKVSRSFALVIQQLDTDLRDAVCIFYLVLRALDTVEDDTSIASEVKVPILKAFHRHIYNSEWHFSCGTKEYKVLMDEFHHVSVAFLELGKGYQEAIENITMRMGEGMAKFICKEVETVDDYDEYCHYVAGLVGLGLSKLFHASGKEDLASDSISNSMGLFLQKTNIIRDYLEDINEIPKSRMFWPREIWSKYANKLEDLKYEENSVKAVHCLNDMV...

XP_057783133.1
MVNLGAILKHPEDLYPMVKLKLAARQAEKQIPAEPHWAFCYSMLHKVSRSFALVIQQLDTDLRDAVCIFYLVLRALDTVEDDTSIASEVKVPILKAFHRHIYNSEWHFSCGTKEYKVLMDEFHHVSVAFLELGKGYQEAIENITMRMGEGMAKFICKEVETVDDYDEYCHYVAGLVGLGLSKLFHASGKEDLASDSISNSMGLFLQKTNIIRDYLEDINEIPKSRMFWPREIWSKYANKLEDLKYEENSVKAVHCLNDMV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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