Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G001732`

染色体: Chr08 坐标: 14566247-14571085 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G001732`
名称	SmilChr08G001732
描述	3-ketoacyl-CoA thiolase 2, peroxisomal-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	14566247 - 14571085 / `+`

ID 对照

NCBI Gene ID	`LOC131001276`
GeneID	`131001276`
locus_tag	`-`
NCBI Name	`LOC131001276`
原始查询	`LOC131001276`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	3-ketoacyl-CoA thiolase 2, peroxisomal-like
产物	3-ketoacyl-CoA thiolase 2%2C peroxisomal-like
Arabidopsis	`AT2G33150` (PKT3) peroxisomal 3-ketoacyl-CoA thiolase 3 [Source:NCBI gene (formerly Entrezgene);Acc:817876] identity=87.2; qcov=0.909; evalue=0; confidence=high
Rice	`Os02g0817700` (OsI57) - identity=76.9; qcov=0.888; evalue=0; confidence=high
GO	GO:0003988 (acetyl-CoA C-acyltransferase activity); GO:0005777 (peroxisome); GO:0006635 (fatty acid beta-oxidation); GO:0010124 (phenylacetate catabolic process)
KEGG	smil00071 (Fatty acid degradation - Salvia miltiorrhiza (redroot sage)); smil00280 (Valine, leucine and isoleucine degradation - Salvia miltiorrhiza (redroot sage)); smil00592 (alpha-Linolenic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01040 (Biosynthesis of unsaturated fatty acids - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01212 (Fatty acid metabolism - Salvia miltiorrhiza (redroot sage)); smil04146 (Peroxisome - Salvia miltiorrhiza (redroot sage))
Pfam	PF00108 (Thiolase_N); PF02803 (Thiolase_C)
InterPro	-
eggNOG	-
NR	GeneID:131001276

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Peroxisome	过氧化物酶体	1.00000	`XP_057783603.1`
2	Cytosol	细胞质基质	0.20000	`XP_057783603.1`
3	Nucleus	细胞核	0.00000	`XP_057783603.1`
4	Chromosome	染色体	0.00000	`XP_057783603.1`
5	Centromere	着丝粒	0.00000	`XP_057783603.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:14566403`	`C`	`T`	EMS_canonical_SNV	stop_gained	40	A1,A10,A14,A19,A25,A7,A8,B104,B105,B128,B129,B134,B135,B15,B17,B2,B21,B25,B55,B59,B67,B68,B7,B74,B85,B97,C1,C17,C23,C28,C29,C33,C41,C5,C58,C73,C78,C83,C85,D10
`Chr8:14566492`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B1,B24,B99,C12,C82
`Chr8:14567532`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A20,B82,C20,C48
`Chr8:14568308`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B140,C82
`Chr8:14568509`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B6
`Chr8:14568863`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B120,B13,B53,C41
`Chr8:14570447`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B34
`Chr8:14570505`	`G`	`GTC`	2bp_insertion	frameshift_variant	94	A1,A10,A14,A15,A22,A25,A4,A7,A9,B102,B103,B105,B108,B11,B111,B113,B114,B119,B128,B129,B13,B131,B134,B135,B136,B140,B15,B17,B2,B21,B25,B31,B32,B36,B4,B40,B44,B46,B49,B51,B52,B53,B55,B56,B57,B62,B63,B64,B69,B7,B71,B74,B77,B80,B85,B94,B97,C1,C10,C15,C2,C21,C23,C24,C26,C27,C28,C29,C33,C35,C38,C4,C41,C5,C51,C54,C55,C62,C71,C72,C73,C76,C78,C79,C8,C80,C81,C82,C83,C84,C85,D2,D6,D9
`Chr8:14570530`	`TCC`	`T`	2bp_deletion	frameshift_variant	9	A15,A5,B44,B52,B80,C16,C19,C40,D3
`Chr8:14570531`	`C`	`CT`	1bp_insertion	frameshift_variant	14	A19,A7,B109,B115,B139,B73,B76,B77,B82,B97,C17,C20,C25,C60
`Chr8:14570534`	`TCC`	`T`	2bp_deletion	frameshift_variant	1	C61
`Chr8:14570534`	`TCC`	`T`	2bp_deletion	CDS_variant	1	C61

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057783603.1

512 aa

256

512

Thiolase_N

Thiolase_C

PF00108 Thiolase_N 98-353 aa PF02803 Thiolase_C 362-476 aa

XP_057783604.1

508 aa

254

508

Thiolase_N

Thiolase_C

PF00108 Thiolase_N 98-353 aa PF02803 Thiolase_C 362-484 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057783603.1`	Pfam	`PF00108`	Thiolase_N	Domain	98	353	2e-77	260.8	Thiolase, N-terminal domain
`XP_057783603.1`	Pfam	`PF02803`	Thiolase_C	Domain	362	476	1.8e-45	154.2	Thiolase, C-terminal domain
`XP_057783604.1`	Pfam	`PF00108`	Thiolase_N	Domain	98	353	1.9e-77	260.8	Thiolase, N-terminal domain
`XP_057783604.1`	Pfam	`PF02803`	Thiolase_C	Domain	362	484	1.8e-49	167.2	Thiolase, C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057927621.1
AACGTAGGATGAATTCATACGGTATAAGATTGAGACATATAGATACAATAATCGTATGTATATTTTGCCATGTATCAGATAATCTCACATTTTTGTCACATTTCCCAATACCAAACCGAAGATATATATACATATTTCAGGCAAGCTTCTTCCGATCAAAACCCGATACAGTTTGTTAATAACTTTTTAGAGAGAGAAACGATGGAGAAAGCAGCTGAGAGGCAGAGAGTTTTGCTGCAGCACCTCCGTCCGTCCTTCAC...

XM_057927620.1
CATACGGTATAAGATTGAGACATATAGATACAATAATCGTATGTATATTTTGCCATGTATCAGATAATCTCACATTTTTGTCACATTTCCCAATACCAAACCGAAGATATATATACATATTTCAGGCAAGCTTCTTCCGATCAAAACCCGATACAGTTTGTTAATAACTTTTTAGAGAGAGAAACGATGGAGAAAGCAGCTGAGAGGCAGAGAGTTTTGCTGCAGCACCTCCGTCCGTCCTTCACTTCATCATCCCTCGA...

CDS

2 records

下载 CDS FASTA

LOC131001276
ATGTATCAGATAATCTCACATTTTTGTCACATTTCCCAATACCAAACCGAAGATATATATACATATTTCAGGCAAGCTTCTTCCGATCAAAACCCGATACAGTTTGTTAATAACTTTTTAGAGAGAGAAACGATGGAGAAAGCAGCTGAGAGGCAGAGAGTTTTGCTGCAGCACCTCCGTCCGTCCTTCACTTCATCATCCCTCGAAGATATTGAATCTTCACTTTCCGCATCTATATGTTCTGCCGGGGATAGTGCAGC...

Protein

2 records

下载 Protein FASTA

XP_057783603.1
MYQIISHFCHISQYQTEDIYTYFRQASSDQNPIQFVNNFLERETMEKAAERQRVLLQHLRPSFTSSSLEDIESSLSASICSAGDSAAYHRSSVFGDDVVIVAAYRTPQCKSKRGGFKDTFPDDLLAPVLRALIEKTNISPAEVGDIVVGSVLAPGSQRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTTNPMAWEGSVNPRVKTMAEAQNCLLPMGITSENVAHRFGVTRQEQ...

XP_057783604.1
MYQIISHFCHISQYQTEDIYTYFRQASSDQNPIQFVNNFLERETMEKAAERQRVLLQHLRPSFTSSSLEDIESSLSASICSAGDSAAYHRSSVFGDDVVIVAAYRTPQCKSKRGGFKDTFPDDLLAPVLRALIEKTNISPAEVGDIVVGSVLAPGSQRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTTNPMAWEGSVNPRVKTMAEAQNCLLPMGITSENVAHRFGVTRQEQ...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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