Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G001781`

染色体: Chr08 坐标: 15017274-15019616 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G001781`
名称	SmilChr08G001781
描述	adenosylhomocysteinase-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	15017274 - 15019616 / `+`

ID 对照

NCBI Gene ID	`LOC131001324`
GeneID	`131001324`
locus_tag	`-`
NCBI Name	`LOC131001324`
原始查询	`LOC131001324`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	adenosylhomocysteinase-like
产物	adenosylhomocysteinase-like
Arabidopsis	`AT4G13940` (HOG1) S-adenosyl-L-homocysteine hydrolase [Source:NCBI gene (formerly Entrezgene);Acc:827028] identity=89.5; qcov=1; evalue=0; confidence=high
Rice	`Os11g0455500` - identity=90.5; qcov=0.979; evalue=0; confidence=high
GO	GO:0004013 (adenosylhomocysteinase activity); GO:0005829 (cytosol); GO:0033353 (L-methionine cycle)
KEGG	smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil00670 (One carbon pool by folate - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage))
Pfam	PF00670 (AdoHcyase_NAD); PF02826 (2-Hacid_dh_C); PF05221 (AdoHcyase); PF07991 (KARI_N)
InterPro	-
eggNOG	-
NR	GeneID:131001324

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057783669.1`
2	Cytoplasm	细胞质	0.80000	`XP_057783669.1`
3	Nucleus	细胞核	0.00000	`XP_057783669.1`
4	Chromosome	染色体	0.00000	`XP_057783669.1`
5	Centromere	着丝粒	0.00000	`XP_057783669.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:15017534`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C4
`Chr8:15017744`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B11,B18,B3,B45,B59
`Chr8:15018002`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B2,B25,C64,C66,C8
`Chr8:15018868`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B23
`Chr8:15018883`	`GA`	`G`	1bp_deletion	frameshift_variant	1	B130
`Chr8:15018883`	`GA`	`G`	1bp_deletion	CDS_variant	1	B130
`Chr8:15018918`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B26,B90,B92
`Chr8:15019017`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr8:15019233`	`GC`	`G`	1bp_deletion	frameshift_variant	1	C42
`Chr8:15019233`	`GC`	`G`	1bp_deletion	CDS_variant	1	C42
`Chr8:15019254`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C64,C66,C8
`Chr8:15019320`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B2

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057783669.1

485 aa

242

485

AdoHcyase

AdoHcyase_NAD

KARI_N

2-Hacid_dh_C

PF05221 AdoHcyase 13-484 aa PF00670 AdoHcyase_NAD 240-403 aa PF07991 KARI_N 260-323 aa PF02826 2-Hacid_dh_C 260-349 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057783669.1`	Pfam	`PF05221`	AdoHcyase	Domain	13	484	2.8e-146	487.1	S-adenosyl-L-homocysteine hydrolase
`XP_057783669.1`	Pfam	`PF00670`	AdoHcyase_NAD	Domain	240	403	2.3e-84	282.2	S-adenosyl-L-homocysteine hydrolase, NAD binding domain
`XP_057783669.1`	Pfam	`PF07991`	KARI_N	Family	260	323	0.00016	22.0	Acetohydroxy acid isomeroreductase, NADPH-binding domain
`XP_057783669.1`	Pfam	`PF02826`	2-Hacid_dh_C	Domain	260	349	9.3e-07	29.1	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057927686.1
AATAAGCAAAAGTATGAGAGGCAAAAATGAAATTATCGGTTTTGACACCCACCACCACCAATACCATCTCTTTATATGTCCCTCCCTCTCCCTCCATCACCCTCGTCCACATCTCTACTCTAAAACCCTCATTTCTCAGATCTGAATCCTCTGCAACTCGCGGCATCCATGGCGCTCCAAATCGAGAAGACTACCTCCGGCCGCGAGTACAAGGTCAAGGACATGTCGCAGGCCGACTTCGGGCGCCTCGAGATCGAGCT...

CDS

1 records

下载 CDS FASTA

LOC131001324
ATGGCGCTCCAAATCGAGAAGACTACCTCCGGCCGCGAGTACAAGGTCAAGGACATGTCGCAGGCCGACTTCGGGCGCCTCGAGATCGAGCTCGCCGAGGTGGAGATGCCGGGCCTCATGTCCTGCCGCACCGAATTCGGCCCCTCCCAGCCCTTCAAGGGGGCTCGGATCACTGGCAGTCTCCACATGACCATCCAGACCGCCGTCCTCATCGAGACCCTCACCGCCCTCGGCGCCGAGGTCAGGTGGTGCTCCTGCAA...

Protein

1 records

下载 Protein FASTA

XP_057783669.1
MALQIEKTTSGREYKVKDMSQADFGRLEIELAEVEMPGLMSCRTEFGPSQPFKGARITGSLHMTIQTAVLIETLTALGAEVRWCSCNIFSTQDHAAAAIARDSAAVFAWKGETLQEYWWCTERALDWGPGGGPDLIVDDGGDTTLLIHEGVKAEEEYEKSGKLPDPSSTDNAEFQIVLTLIRDGLKGDPTKYRKMNERLVGVSEETTTGVKRLYQMQANGTLLFPAINVNDSVTKSKFDNLYGCRHSLPDGLMRATDVMI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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