Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G002233`

染色体: Chr08 坐标: 20454682-20458435 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G002233`
名称	SmilChr08G002233
描述	serine hydroxymethyltransferase, mitochondrial
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	20454682 - 20458435 / `+`

ID 对照

NCBI Gene ID	`LOC131001763`
GeneID	`131001763`
locus_tag	`-`
NCBI Name	`LOC131001763`
原始查询	`LOC131001763`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	serine hydroxymethyltransferase, mitochondrial
产物	serine hydroxymethyltransferase%2C mitochondrial
Arabidopsis	`AT4G37930` (SHM1) serine transhydroxymethyltransferase 1 [Source:NCBI gene (formerly Entrezgene);Acc:829949] identity=89; qcov=1.01; evalue=0; confidence=high
Rice	`Os03g0738400` (OsSHM1) - identity=87.8; qcov=1.01; evalue=0; confidence=high
GO	GO:0004372 (glycine hydroxymethyltransferase activity); GO:0005737 (cytoplasm); GO:0006565 (L-serine catabolic process); GO:0008270 (zinc ion binding); GO:0019264 (GO:0019264); GO:0030170 (pyridoxal phosphate binding); GO:0035999 (tetrahydrofolate interconversion); GO:0046655 (folic acid metabolic process); GO:0050897 (cobalt ion binding); GO:0070905 (serine binding)
KEGG	smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00460 (Cyanoamino acid metabolism - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil00670 (One carbon pool by folate - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage)); smil04981 (Folate transport and metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00464 (SHMT)
InterPro	-
eggNOG	-
NR	GeneID:131001763

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057784313.1`
2	Mitochondrion matrix	线粒体基质	1.00000	`XP_057784313.1`
3	Nucleus	细胞核	0.00000	`XP_057784313.1`
4	Chromosome	染色体	0.00000	`XP_057784313.1`
5	Centromere	着丝粒	0.00000	`XP_057784313.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:20455845`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B70
`Chr8:20456915`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B41,B82,B95,C60
`Chr8:20456957`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B41,B82,B95,C60
`Chr8:20457160`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B41,B95,C60
`Chr8:20457207`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B118,B13,B8,D11
`Chr8:20457224`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B1,C8
`Chr8:20457228`	`C`	`T`	EMS_canonical_SNV	stop_gained	2	C28,C38
`Chr8:20457228`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C28,C38
`Chr8:20457413`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B52
`Chr8:20457551`	`AC`	`A`	1bp_deletion	frameshift_variant	12	B134,B136,B3,B95,B98,C21,C24,C25,C48,C73,C78,C84
`Chr8:20458070`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B29
`Chr8:20458130`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B103

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057784313.1

514 aa

257

514

SHMT

PF00464 SHMT 53-450 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057784313.1`	Pfam	`PF00464`	SHMT	Domain	53	450	1.1e-215	716.5	Serine hydroxymethyltransferase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057928330.1
CCGTTAGTTAGCTGGTAGTGCAAATTCAAACCGGATAAACCAATAAAGCGCTGAAATCACAAAATCTTATTGCTTTGAGGCCGACGACAAACAAGAACCAGAAATATTGTTCGATTTTCCGCCACCACCCAAAACCTCACCCAAAAAACACATCCATTCGCCCACAACAACACACGATCTCGCATGTCTCCTGCTCACACTCACACTTAGTGAGAGAAAATACAGAGAGAGAAGATGATGTTGGCAATGGCTGTGAGGAG...

CDS

1 records

下载 CDS FASTA

LOC131001763
ATGATGTTGGCAATGGCTGTGAGGAGGCTTTCCTCCTCCATCTCCAAACCTCTCAAGCGCGGCGGCTCTCTCTATCACATGTCTTCGTTGCCTAATGAAGCTGTGTACGAGAAGGAAAAGAATGGCGTCGCGTGGCCGAAGCAGTTGAATGCTCCGTTGGAGGTCGTTGATCCCGAGATTGCTGACATTATCGAGCACGAAAAGGCTAGACAATGGAAGGGGCTTGAGCTCATTCCCTCGGAAAATTTCACTTCTGTGTC...

Protein

1 records

下载 Protein FASTA

XP_057784313.1
MMLAMAVRRLSSSISKPLKRGGSLYHMSSLPNEAVYEKEKNGVAWPKQLNAPLEVVDPEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFRLDPAKWGVNVQPLSGSPANFHVYTALLKPHDRIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLNESTGYIDYDQLEKSAVLFRPKLIVAGASAYARLYDYDRIRKVCDKQKAVLLADMAHIS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器