Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G002366`

染色体: Chr08 坐标: 22473901-22492490 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G002366`
名称	SmilChr08G002366
描述	brefeldin A-inhibited guanine nucleotide-exchange protein 5-like
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	22473901 - 22492490 / `-`

ID 对照

NCBI Gene ID	`LOC131001887`
GeneID	`131001887`
locus_tag	`-`
NCBI Name	`LOC131001887`
原始查询	`LOC131001887`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	brefeldin A-inhibited guanine nucleotide-exchange protein 5-like
产物	brefeldin A-inhibited guanine nucleotide-exchange protein 5-like
Arabidopsis	`AT3G43300` (ATMIN7) HOPM interactor 7 [Source:NCBI gene (formerly Entrezgene);Acc:823405] identity=67; qcov=1; evalue=0; confidence=high
Rice	`Os07g0564700` - identity=56.4; qcov=0.174; evalue=1.54e-110; confidence=weak
GO	GO:0005085 (guanyl-nucleotide exchange factor activity); GO:0005802 (trans-Golgi network); GO:0032012 (regulation of ARF protein signal transduction)
KEGG	-
Pfam	PF01369 (Sec7); PF09324 (Sec7-like_HDS); PF12783 (Sec7-like_HUS); PF16206 (Mon2_C); PF16213 (DCB); PF20252 (BIG2_C); PF23325 (TPR_28)
InterPro	-
eggNOG	-
NR	GeneID:131001887

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Golgi apparatus	高尔基体	0.80000	`XP_057784505.1`
2	Cytosol	细胞质基质	0.40000	`XP_057784505.1`
3	Trans-golgi network	Trans-golgi network	0.20000	`XP_057784505.1`
4	Nucleus	细胞核	0.00000	`XP_057784505.1`
5	Chromosome	染色体	0.00000	`XP_057784505.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:22475225`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B1,B108,B12,C85
`Chr8:22475266`	`TG`	`T`	1bp_deletion	frameshift_variant	1	A18
`Chr8:22475266`	`TG`	`T`	1bp_deletion	CDS_variant	1	A18
`Chr8:22477470`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B44,D3
`Chr8:22477612`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B1,B108,B12,C85
`Chr8:22477616`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B135,B35,C61,C62
`Chr8:22478141`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr8:22480922`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B66,B8
`Chr8:22482232`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C23
`Chr8:22482361`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B48
`Chr8:22482415`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B1,B107,B108,B12,C85
`Chr8:22483107`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B67

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057784505.1

1765 aa

882

1765

DCB

Sec7-like_HUS

Sec7

Sec7-like_HDS

Mon2_C

TPR_28

BIG2_C

PF16213 DCB 99-254 aa PF12783 Sec7-like_HUS 350-500 aa PF01369 Sec7 595-776 aa PF09324 Sec7-like_HDS 1088-1170 aa PF16206 Mon2_C 1245-1308 aa PF23325 TPR_28 1247-1342 aa PF20252 BIG2_C 1565-1755 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057784505.1`	Pfam	`PF16213`	DCB	Repeat	99	254	8.5e-30	104.5	Mon2/Sec7/BIG1-like, dimerisation and cyclophilin-binding domain
`XP_057784505.1`	Pfam	`PF12783`	Sec7-like_HUS	Repeat	350	500	7.1e-39	133.9	Mon2/Sec7/BIG1-like, HUS domain
`XP_057784505.1`	Pfam	`PF01369`	Sec7	Domain	595	776	1.2e-70	237.6	Sec7 domain
`XP_057784505.1`	Pfam	`PF09324`	Sec7-like_HDS	Domain	1088	1170	1.6e-30	105.5	Mon2/Sec7/BIG1-like, HDS
`XP_057784505.1`	Pfam	`PF16206`	Mon2_C	Repeat	1245	1308	5.4e-07	28.9	C-terminal region of Mon2 protein
`XP_057784505.1`	Pfam	`PF23325`	TPR_28	Repeat	1247	1342	1.7e-10	41.8	GBF1-like, tetratrico peptide repeat region
`XP_057784505.1`	Pfam	`PF20252`	BIG2_C	Domain	1565	1755	3.1e-26	93.2	BIG2 C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

6 records

下载 cDNA FASTA

XR_009094052.1
AATCTAAAACGAAAGGCGCATTATCGGTTAACAGAGATCTCCACTCTCTCTCTCTCTCTCTCTCTCTCTTAATTGTTCCATGGCAGATCTCTGATTTGCTGATACTAAAGATATTTACGCAATCTCCGGTTCGTGAGCAAAACGAGGGGATTGAGTTAAACTGAGTTGAACTGAGTTGAAGAAATGGCGGGGGCCGCGGCGGGTGGATTCGTGACGCGAGCATTTGAGTCGATGCTCAAGGAGTGTACTCTCAGGAAGTA...

XR_009094053.1
AATCTAAAACGAAAGGCGCATTATCGGTTAACAGAGATCTCCACTCTCTCTCTCTCTCTCTCTCTCTCTTAATTGTTCCATGGCAGATCTCTGATTTGCTGATACTAAAGATATTTACGCAATCTCCGGTTCGTGAGCAAAACGAGGGGATTGAGTTAAACTGAGTTGAACTGAGTTGAAGAAATGGCGGGGGCCGCGGCGGGTGGATTCGTGACGCGAGCATTTGAGTCGATGCTCAAGGAGTGTACTCTCAGGAAGTA...

CDS

1 records

下载 CDS FASTA

LOC131001887
ATGGCGGGGGCCGCGGCGGGTGGATTCGTGACGCGAGCATTTGAGTCGATGCTCAAGGAGTGTACTCTCAGGAAGTACACTGCTCTGCAGGCCGCCATTCAGGCTTATATAGACAACGGGAAGGAGTCTGGTCAGCAATCGAACACTGGTGAGAGTAATGAAGCTCAACCAGCAACTTCTAAGAAAAGTTCTTCTGAGCCTGATAGCGGGGCTGAAGAAGCTGAGATGGGAACTGATAATTCAAATAGAAATCCATCTTC...

Protein

1 records

下载 Protein FASTA

XP_057784505.1
MAGAAAGGFVTRAFESMLKECTLRKYTALQAAIQAYIDNGKESGQQSNTGESNEAQPATSKKSSSEPDSGAEEAEMGTDNSNRNPSSVEEIEPVERTTSSSVSIRMVLANAGHTLSGAEAELVLNPLRLAFETKNTKVVELALDCLHKLIEYNHLEGDPGLDGGKDAQLFTDIFNMVCRTVDNSSPDSTTLQVLKVLLTAVASTKLRVHGELLLAVIKICYNIALHSKSPINQATSKAMLTQMLSIIFRRMEADVVSSNE...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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