Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G002422`

染色体: Chr08 坐标: 23009078-23016751 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G002422`
名称	SmilChr08G002422
描述	inositol 1,3,4-trisphosphate 5/6-kinase 4
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	23009078 - 23016751 / `+`

ID 对照

NCBI Gene ID	`LOC131001941`
GeneID	`131001941`
locus_tag	`-`
NCBI Name	`LOC131001941`
原始查询	`LOC131001941`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	inositol 1,3,4-trisphosphate 5/6-kinase 4
产物	inositol 1%2C3%2C4-trisphosphate 5/6-kinase 4
Arabidopsis	`AT2G43980` (ITPK4) inositol 1,3,4-trisphosphate 5/6-kinase 4 [Source:NCBI gene (formerly Entrezgene);Acc:819003] identity=49.8; qcov=0.978; evalue=1.01e-160; confidence=high
Rice	`Os09g0518700` (OsITPK6) - identity=49.5; qcov=1; evalue=1.06e-152; confidence=high
GO	GO:0000287 (magnesium ion binding); GO:0005524 (ATP binding); GO:0005737 (cytoplasm); GO:0032957 (inositol trisphosphate metabolic process); GO:0047325 (inositol-3,4,5,6-tetrakisphosphate 1-kinase activity); GO:0052725 (inositol-1,3,4-trisphosphate 6-kinase activity); GO:0052726 (inositol-1,3,4-trisphosphate 5-kinase activity)
KEGG	smil00562 (Inositol phosphate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage))
Pfam	PF05770 (Ins134_P3_kin); PF28688 (HAD_ITPK4_N)
InterPro	-
eggNOG	-
NR	GeneID:131001941

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057784574.1`
2	Cytoplasm	细胞质	0.40000	`XP_057784574.1`
3	Nucleus	细胞核	0.20000	`XP_057784574.1`
4	Chromosome	染色体	0.00000	`XP_057784574.1`
5	Centromere	着丝粒	0.00000	`XP_057784574.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:23009175`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B118,B44,B60
`Chr8:23009266`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D3
`Chr8:23011699`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr8:23011730`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C73
`Chr8:23012790`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A23
`Chr8:23013750`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A23
`Chr8:23015085`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B6
`Chr8:23015538`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C48
`Chr8:23015729`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B70,C48,C62
`Chr8:23015807`	`G`	`GA`	1bp_insertion	frameshift_variant	123	A1,A11,A13,A14,A15,A16,A18,A2,A20,A23,A25,A3,A5,A7,A8,A9,B10,B104,B105,B106,B108,B109,B111,B112,B114,B12,B120,B123,B124,B126,B139,B14,B140,B15,B16,B21,B23,B25,B28,B31,B33,B38,B40,B41,B48,B49,B51,B52,B53,B59,B61,B64,B65,B66,B67,B68,B7,B71,B75,B76,B79,B81,B82,B87,B88,B89,B91,B93,B94,B95,B97,B98,B99,C12,C13,C15,C18,C2,C21,C22,C23,C24,C25,C27,C28,C29,C3,C32,C33,C34,C35,C37,C4,C40,C42,C43,C44,C47,C49,C5,C51,C55,C57,C58,C60,C63,C65,C67,C68,C7,C72,C73,C74,C79,C82,C84,C86,C9,D11,D4,D7,D8,D9
`Chr8:23015810`	`AG`	`A`	1bp_deletion	frameshift_variant	124	A1,A11,A13,A14,A15,A16,A18,A2,A20,A23,A25,A3,A5,A7,A8,A9,B10,B104,B105,B106,B108,B109,B111,B112,B114,B12,B120,B123,B124,B126,B139,B14,B140,B15,B16,B21,B23,B25,B28,B31,B33,B38,B40,B41,B48,B49,B51,B52,B53,B59,B61,B64,B65,B66,B67,B68,B7,B71,B75,B76,B79,B81,B82,B87,B88,B89,B91,B93,B94,B95,B97,B98,B99,C12,C13,C15,C18,C2,C21,C22,C23,C24,C25,C27,C28,C29,C3,C32,C33,C34,C35,C37,C4,C40,C42,C43,C44,C47,C49,C5,C51,C55,C57,C58,C60,C63,C65,C67,C68,C7,C72,C73,C74,C79,C8,C82,C84,C86,C9,D11,D4,D7,D8,D9

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057784574.1

507 aa

254

507

HAD_ITPK4_N

Ins134_P3_kin

PF28688 HAD_ITPK4_N 1-162 aa PF05770 Ins134_P3_kin 297-480 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057784574.1`	Pfam	`PF28688`	HAD_ITPK4_N	Domain	1	162	4.4e-40	137.9	ITPK4, N-terminal HAD-like domain
`XP_057784574.1`	Pfam	`PF05770`	Ins134_P3_kin	Domain	297	480	4.3e-26	92.4	Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057928591.1
ACACTCTCGCAAACTGAAAACCTCTGCATGCATTACATCTCACCAGAACAAATTCACATAGAGAGAGATAGAGGATGGCTGGAGTGAAAGGGATTGTGCTGGATTCGTCTGTACTATTGCCGTCGGCCGATGATGAAGTAAACGGAGATGCTGGCCTCCGCTCCGGCGCCGAATTTTTGCTTCGCAAGCTGCGCTACTGCAATATCCCAATCGGCATATCTCATGAACAGGGTCTTTTGAGCTTGAAGGAGTGCCTTCTT...

CDS

1 records

下载 CDS FASTA

LOC131001941
ATGGCTGGAGTGAAAGGGATTGTGCTGGATTCGTCTGTACTATTGCCGTCGGCCGATGATGAAGTAAACGGAGATGCTGGCCTCCGCTCCGGCGCCGAATTTTTGCTTCGCAAGCTGCGCTACTGCAATATCCCAATCGGCATATCTCATGAACAGGGTCTTTTGAGCTTGAAGGAGTGCCTTCTTAAAGAGGTAGCCAAAACCTACTTATGTACAATCTTCTGCTTATCGCCAGAAGATGATATTTCAAGTGAGGTTGA...

Protein

1 records

下载 Protein FASTA

XP_057784574.1
MAGVKGIVLDSSVLLPSADDEVNGDAGLRSGAEFLLRKLRYCNIPIGISHEQGLLSLKECLLKEVAKTYLCTIFCLSPEDDISSEVDRIWEGKEGKLIHVISCGREDLSQKKNGSHILKVIVGSAERQASNGSDYALTAEMLSISINKLQELPLLVCSMNRKAAGEEVSAVGYVMKPSREEDFAKRGAFPLCPTQNGLIFLPLNYELPIPSQLQLVDAILHKATDEILAVDMASPSEISDKVTFTRNLQELQRYVEGQTD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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