Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr08G002452`

染色体: Chr08 坐标: 23326566-23330251 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr08G002452`
名称	SmilChr08G002452
描述	alcohol dehydrogenase-like 7
染色体 / SeqID	Chr08 / NC_080394.1
坐标与链方向	23326566 - 23330251 / `-`

ID 对照

NCBI Gene ID	`LOC131001971`
GeneID	`131001971`
locus_tag	`-`
NCBI Name	`LOC131001971`
原始查询	`LOC131001971`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	alcohol dehydrogenase-like 7
产物	alcohol dehydrogenase-like 7
Arabidopsis	`AT5G42250` (AT5G42250) Zinc-binding alcohol dehydrogenase family protein [Source:NCBI gene (formerly Entrezgene);Acc:834230] identity=70; qcov=0.979; evalue=0; confidence=high
Rice	`Os03g0189400` - identity=60.4; qcov=0.969; evalue=1.93e-172; confidence=high
GO	GO:0004024 (GO:0004024); GO:0005829 (cytosol); GO:0008270 (zinc ion binding); GO:0046294 (formaldehyde catabolic process); GO:0051903 (S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00071 (Fatty acid degradation - Salvia miltiorrhiza (redroot sage)); smil00350 (Tyrosine metabolism - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00107 (ADH_zinc_N); PF08240 (ADH_N)
InterPro	-
eggNOG	-
NR	GeneID:131001971

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057784615.1`
2	Cytoplasm	细胞质	0.60000	`XP_057784615.1`
3	Nucleus	细胞核	0.00000	`XP_057784615.1`
4	Chromosome	染色体	0.00000	`XP_057784615.1`
5	Centromere	着丝粒	0.00000	`XP_057784615.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr8:23326899`	`C`	`CT`	1bp_insertion	frameshift_variant	9	A10,B120,B14,B69,C1,C27,C4,C45,C56
`Chr8:23327272`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C49
`Chr8:23327501`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B65
`Chr8:23327625`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C10
`Chr8:23327652`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B56,B96
`Chr8:23328015`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C39,C45,C80
`Chr8:23328659`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B119,B72,C26
`Chr8:23328750`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	B65
`Chr8:23328750`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B65
`Chr8:23328753`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B65
`Chr8:23328762`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B65
`Chr8:23328806`	`ATC`	`A`	2bp_deletion	frameshift_variant	1	B65

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057784615.1

388 aa

194

388

ADH_N

ADH_zinc_N

PF08240 ADH_N 42-171 aa PF00107 ADH_zinc_N 213-337 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057784615.1`	Pfam	`PF08240`	ADH_N	Domain	42	171	3.1e-20	73.1	Alcohol dehydrogenase GroES-like domain
`XP_057784615.1`	Pfam	`PF00107`	ADH_zinc_N	Domain	213	337	1.5e-26	93.6	Zinc-binding dehydrogenase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057928632.1
TGAAACATCCATCAACAACCCACCATTTCGTCATCTCCAAAATCATTTTCTACTTTAATTTCCTTCTGAAGGTTGCAATGGCTGACGCTGGCGTTGACTGTAGCAAAAATGCCGGCAAACCCATAAAATGCCGAGCGGCGGTGGCGAGGAAATCTGGGGCTCCCCTAGTGATAGAAGACGTGATCGTGGAGCCTCCTAAATCCCACGAAGTTCGGATCAAAATTATTTGCACTTCTCTCTGTCACAGCGATGTTACTTTC...

CDS

1 records

下载 CDS FASTA

LOC131001971
ATGGCTGACGCTGGCGTTGACTGTAGCAAAAATGCCGGCAAACCCATAAAATGCCGAGCGGCGGTGGCGAGGAAATCTGGGGCTCCCCTAGTGATAGAAGACGTGATCGTGGAGCCTCCTAAATCCCACGAAGTTCGGATCAAAATTATTTGCACTTCTCTCTGTCACAGCGATGTTACTTTCTTGAACTTGAACGACCCTCCGGCATGTTTTCCAAGAATTCTGGGACATGAAGCCGTCGGTGTGGTGGAGAGTGTTGG...

Protein

1 records

下载 Protein FASTA

XP_057784615.1
MADAGVDCSKNAGKPIKCRAAVARKSGAPLVIEDVIVEPPKSHEVRIKIICTSLCHSDVTFLNLNDPPACFPRILGHEAVGVVESVGDSVSELVEGDMVIPIFVPDCGECIDCKSEKSNLCTEFPFRIDPWMHDGSSRFKDLNGETLYHFLFVSSFTEYTVVHVANVTKIDSTIPPNRACLLSCGVSTGVGAAWRTADVKPGSTVAIFGLGSIGLAVAEGARLCGAARIIGIDVNPEKMEISKRFGVTDFVDSTSCVEKR...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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