Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G004749`

染色体: Chr01 坐标: 65661387-65669695 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G004749`
名称	SmilChr01G004749
描述	topless-related protein 1-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	65661387 - 65669695 / `+`

ID 对照

NCBI Gene ID	`LOC131005093`
GeneID	`131005093`
locus_tag	`-`
NCBI Name	`LOC131005093`
原始查询	`LOC131005093`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	topless-related protein 1-like
产物	topless-related protein 1-like
Arabidopsis	`AT1G80490` (TPR1) TOPLESS-related 1 [Source:NCBI gene (formerly Entrezgene);Acc:844388] identity=76.8; qcov=1.01; evalue=0; confidence=high
Rice	`Os03g0254700` (OsWD40-66) protein TPR3-like [Source:NCBI gene (formerly Entrezgene);Acc:4332285] identity=76; qcov=1.01; evalue=0; confidence=high
GO	GO:0005515 (protein binding); GO:0006355 (regulation of DNA-templated transcription)
KEGG	-
Pfam	PF00400 (WD40); PF17814 (LisH_TPL); PF21359 (zf_topless); PF21889 (TPR1-like_2nd)
InterPro	-
eggNOG	-
NR	GeneID:131005093

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	0.80000	`XP_057787882.1`
2	Nucleus	细胞核	0.60000	`XP_057787882.1`
3	Cytosol	细胞质基质	0.60000	`XP_057787882.1`
4	Chromosome	染色体	0.00000	`XP_057787882.1`
5	Centromere	着丝粒	0.00000	`XP_057787882.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:65662539`	`G`	`A`	EMS_canonical_SNV	stop_gained	235	A1,A10,A13,A14,A15,A16,A18,A19,A2,A20,A21,A22,A23,A24,A25,A3,A5,A6,A8,A9,B1,B10,B100,B101,B102,B103,B104,B105,B106,B107,B108,B109,B11,B110,B111,B112,B113,B114,B115,B117,B118,B119,B12,B120,B121,B122,B123,B124,B125,B126,B127,B128,B129,B13,B130,B131,B132,B133,B134,B135,B138,B139,B14,B140,B15,B17,B18,B19,B2,B20,B21,B23,B24,B25,B26,B27,B28,B3,B30,B31,B32,B33,B34,B36,B38,B39,B4,B40,B41,B42,B43,B44,B45,B46,B47,B48,B49,B5,B50,B51,B52,B53,B54,B55,B56,B57,B59,B6,B60,B61,B63,B64,B65,B66,B67,B68,B69,B7,B70,B71,B72,B73,B74,B75,B76,B77,B78,B79,B8,B80,B81,B83,B84,B85,B86,B87,B89,B9,B90,B91,B92,B93,B94,B95,B96,B97,B98,B99,C10,C11,C12,C13,C14,C15,C16,C17,C18,C19,C2,C20,C22,C23,C24,C25,C26,C27,C28,C29,C3,C30,C32,C33,C34,C35,C36,C37,C38,C4,C40,C41,C42,C44,C45,C46,C47,C48,C49,C5,C50,C51,C53,C54,C55,C56,C57,C59,C6,C60,C61,C62,C64,C65,C67,C68,C69,C7,C70,C71,C72,C73,C75,C76,C77,C78,C79,C8,C80,C81,C82,C83,C84,C85,C86,C87,C9,D1,D10,D11,D2,D3,D4,D5,D6,D7,D9
`Chr1:65662544`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B25,B38,B59,C27,C55
`Chr1:65662605`	`TG`	`T`	1bp_deletion	frameshift_variant	4	B32,B4,B57,B99
`Chr1:65662605`	`TG`	`T`	1bp_deletion	CDS_variant	4	B32,B4,B57,B99
`Chr1:65662611`	`TTG`	`T`	2bp_deletion	frameshift_variant	4	B32,B4,B57,B99
`Chr1:65662611`	`TTG`	`T`	2bp_deletion	CDS_variant	4	B32,B4,B57,B99
`Chr1:65662832`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B113
`Chr1:65662841`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B113
`Chr1:65663282`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B25
`Chr1:65663408`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A11,B139,B59
`Chr1:65663546`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A5,B11,B69
`Chr1:65664592`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B138,B69

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057787882.1

1130 aa

565

1130

LisH_TPL

TPR1-like_2nd

zf_topless

WD40

PF17814 LisH_TPL 5-34 aa PF21889 TPR1-like_2nd 37-161 aa PF21359 zf_topless 164-204 aa PF00400 WD40 459-493 aa PF00400 WD40 499-536 aa PF00400 WD40 912-947 aa

XP_057787883.1

1130 aa

565

1130

LisH_TPL

TPR1-like_2nd

zf_topless

WD40

PF17814 LisH_TPL 5-34 aa PF21889 TPR1-like_2nd 37-161 aa PF21359 zf_topless 164-204 aa PF00400 WD40 459-493 aa PF00400 WD40 499-536 aa PF00400 WD40 912-947 aa

XP_057787884.1

1129 aa

564

1129

LisH_TPL

TPR1-like_2nd

zf_topless

WD40

PF17814 LisH_TPL 5-34 aa PF21889 TPR1-like_2nd 37-161 aa PF21359 zf_topless 164-204 aa PF00400 WD40 458-492 aa PF00400 WD40 498-535 aa PF00400 WD40 911-946 aa

XP_057787885.1

1129 aa

564

1129

LisH_TPL

TPR1-like_2nd

zf_topless

WD40

PF17814 LisH_TPL 5-34 aa PF21889 TPR1-like_2nd 37-161 aa PF21359 zf_topless 164-204 aa PF00400 WD40 458-492 aa PF00400 WD40 498-535 aa PF00400 WD40 911-946 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057787882.1`	Pfam	`PF17814`	LisH_TPL	Domain	5	34	4e-13	49.5	LisH-like dimerisation domain
`XP_057787882.1`	Pfam	`PF21889`	TPR1-like_2nd	Domain	37	161	1.3e-60	203.9	TPR1-like, CTLH-containing domain
`XP_057787882.1`	Pfam	`PF21359`	zf_topless	Domain	164	204	2.1e-24	85.5	TOPLESS, zinc finger domain
`XP_057787882.1`	Pfam	`PF00400`	WD40	Repeat	459	493	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787882.1`	Pfam	`PF00400`	WD40	Repeat	499	536	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787882.1`	Pfam	`PF00400`	WD40	Repeat	912	947	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787883.1`	Pfam	`PF17814`	LisH_TPL	Domain	5	34	4e-13	49.5	LisH-like dimerisation domain
`XP_057787883.1`	Pfam	`PF21889`	TPR1-like_2nd	Domain	37	161	1.3e-60	203.9	TPR1-like, CTLH-containing domain
`XP_057787883.1`	Pfam	`PF21359`	zf_topless	Domain	164	204	2.1e-24	85.5	TOPLESS, zinc finger domain
`XP_057787883.1`	Pfam	`PF00400`	WD40	Repeat	459	493	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787883.1`	Pfam	`PF00400`	WD40	Repeat	499	536	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787883.1`	Pfam	`PF00400`	WD40	Repeat	912	947	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787884.1`	Pfam	`PF17814`	LisH_TPL	Domain	5	34	4e-13	49.5	LisH-like dimerisation domain
`XP_057787884.1`	Pfam	`PF21889`	TPR1-like_2nd	Domain	37	161	1.3e-60	203.9	TPR1-like, CTLH-containing domain
`XP_057787884.1`	Pfam	`PF21359`	zf_topless	Domain	164	204	2.1e-24	85.5	TOPLESS, zinc finger domain
`XP_057787884.1`	Pfam	`PF00400`	WD40	Repeat	458	492	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787884.1`	Pfam	`PF00400`	WD40	Repeat	498	535	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787884.1`	Pfam	`PF00400`	WD40	Repeat	911	946	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787885.1`	Pfam	`PF17814`	LisH_TPL	Domain	5	34	4e-13	49.5	LisH-like dimerisation domain
`XP_057787885.1`	Pfam	`PF21889`	TPR1-like_2nd	Domain	37	161	1.3e-60	203.9	TPR1-like, CTLH-containing domain
`XP_057787885.1`	Pfam	`PF21359`	zf_topless	Domain	164	204	2.1e-24	85.5	TOPLESS, zinc finger domain
`XP_057787885.1`	Pfam	`PF00400`	WD40	Repeat	458	492	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787885.1`	Pfam	`PF00400`	WD40	Repeat	498	535	1.4e-32	111.4	WD domain, G-beta repeat
`XP_057787885.1`	Pfam	`PF00400`	WD40	Repeat	911	946	1.4e-32	111.4	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057931900.1
TATATGTTGCTGCAATCAAGGTTGTAATCCCCTTTCCTCCAACGATAGTCTAGAGAGAGAAACCCCTTTGTCTTTGTATGCATATTTGTATGTGTATGTAATATGTATGTATCTATTATTGTGAGATACATATAGAGAGGGAATACATGTAGACACACCTTCACTCCCTTTTAGAGAGAGAGAGAGAGAGAGATCGAACCCTACTTTCACCTTGAGTTCATCGCTCTCTGCTTCAGTTGATTTTAAAAATCCAAACTTTT...

XM_057931901.1
TCCCCTTTCCTCCAACGATAGTCTAGAGAGAGAAACCCCTTTGTCTTTGTATGCATATTTGTATGTGTATGTAATATGTATGTATCTATTATTGTGAGATACATATAGAGAGGGAATACATGTAGACACACCTTCACTCCCTTTTAGAGAGAGAGAGAGAGAGAGATCGAACCCTACTTTCACCTTGAGTTCATCGCTCTCTGCTTCAGTTGATTTTAAAAATCCAAACTTTTTCCCTTAATTGAGGTGATCTAAAGGAT...

CDS

4 records

下载 CDS FASTA

LOC131005093
ATGTCCTCTCTGAGTCGAGAACTTGTTTTCTTGATTTTACAATTCCTGGATGAAGAGAAGTTTAAGGAGACTGTTCACAAGCTCGAGCAAGAATCGGGGTTTTTCTTTAACATGAAGCATTTTGAGGATGAGGTGCACAATGGGAACTGGGAGGAGGTTGAAAGATACCTCTCTGGCTTCACAAAAGTGGACGACAATCGCTATTCGATGAAGTTGTTTTTTGAGATTAGAAAGCAGAAGTACCTTGAAGCATTGGATAA...

Protein

4 records

下载 Protein FASTA

XP_057787882.1
MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKHFEDEVHNGNWEEVERYLSGFTKVDDNRYSMKLFFEIRKQKYLEALDKHDLSKAVDVLVKDLKVFSSFNEELFKEITQLLTLENFRDNEQLSKYGDTRSARAVMLVELKKLIEANPLFRDKLQFPNLKNSRLRTLINQSLNWQHQLCKSPKPNPDIKTLFVDHSCGQPNGASTPSQASNPLLGGAVPKPGGFPPLAAHVPFQPMPVPVPTPLASWMSNPPA...

XP_057787883.1
MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKHFEDEVHNGNWEEVERYLSGFTKVDDNRYSMKLFFEIRKQKYLEALDKHDLSKAVDVLVKDLKVFSSFNEELFKEITQLLTLENFRDNEQLSKYGDTRSARAVMLVELKKLIEANPLFRDKLQFPNLKNSRLRTLINQSLNWQHQLCKSPKPNPDIKTLFVDHSCGQPNGASTPSQASNPLLGGAVPKPGGFPPLAAHVPFQPMPVPVPTPLASWMSNPPA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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