Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G004837`

染色体: Chr01 坐标: 66502369-66509300 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G004837`
名称	SmilChr01G004837
描述	methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	66502369 - 66509300 / `-`

ID 对照

NCBI Gene ID	`LOC131005174`
GeneID	`131005174`
locus_tag	`-`
NCBI Name	`LOC131005174`
原始查询	`LOC131005174`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
产物	methylmalonate-semialdehyde dehydrogenase [acylating]%2C mitochondrial
Arabidopsis	`AT2G14170` (ALDH6B2) aldehyde dehydrogenase 6B2 [Source:NCBI gene (formerly Entrezgene);Acc:815903] identity=86.9; qcov=0.998; evalue=0; confidence=high
Rice	`Os07g0188800` (OsALDH6B2) - identity=82.3; qcov=1; evalue=0; confidence=high
GO	GO:0004491 (methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity); GO:0005739 (mitochondrion); GO:0006210 (thymine catabolic process); GO:0006574 (L-valine catabolic process); GO:0018478 (malonate-semialdehyde dehydrogenase (acetylating) activity)
KEGG	smil00280 (Valine, leucine and isoleucine degradation - Salvia miltiorrhiza (redroot sage)); smil00410 (beta-Alanine metabolism - Salvia miltiorrhiza (redroot sage)); smil00562 (Inositol phosphate metabolism - Salvia miltiorrhiza (redroot sage)); smil00640 (Propanoate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00171 (Aldedh)
InterPro	-
eggNOG	-
NR	GeneID:131005174

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057787987.1`
2	Cytoplasm	细胞质	1.00000	`XP_057787988.1`
3	Mitochondrion matrix	线粒体基质	1.00000	`XP_057787987.1`
4	Cytosol	细胞质基质	0.20000	`XP_057787988.1`
5	Nucleus	细胞核	0.00000	`XP_057787987.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:66503226`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B66
`Chr1:66503615`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A20,B137,B44,C49
`Chr1:66504755`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B132,B59,D3
`Chr1:66505347`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A20,B137,B44,C49
`Chr1:66507170`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C5
`Chr1:66507325`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C80
`Chr1:66507548`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B107,B33,C22,C29
`Chr1:66507585`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C6

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057787987.1

536 aa

268

536

Aldedh

PF00171 Aldedh 51-515 aa

XP_057787988.1

429 aa

214

429

Aldedh

PF00171 Aldedh 1-408 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057787987.1`	Pfam	`PF00171`	Aldedh	Family	51	515	1e-147	493.2	Aldehyde dehydrogenase family
`XP_057787988.1`	Pfam	`PF00171`	Aldedh	Family	1	408	8.5e-127	424.2	Aldehyde dehydrogenase family

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057932004.1
GAATAAATTAATCCAAATAAACGATTTAAAATAAGCATACAGAGATAGAAACAGAGAGAGAGAGAGAGAGACAGAGAGAGAAAGAGAGAGAGAGAGAGAGGTGGCACACTTCATTTTCACTTCTTCAGCAAAAACTCAAAATGTTGCAGTTTTCGATCCAACGAGTGAGAGGCATGAGGAGGTTGAGTCCAGGAATATTTTGGGCTGCAAATTCTCGTCTCTCGACTGTTTCTGAACCATCTTCGAGGCCTGGCAACTCC...

XM_057932005.1
GAGTAAGCAAAGTTTGGAGAGGATTCCGAATCTAATTGGAGGTAGGTTTGTAGACTCACATTCAACCGACTCCATTGATGTCATAAATCCGGCAACACAAGAGGTTGTTTCACAAGTGCCTCTGACAACAAAAGAGGAGTTCAAATCTGCAGTATCGGCTGCAAAAGAGGCATTTCCATCCTGGCGAAACACACCTATTACGACACGTCAGCGCGTCATGTTGAAGCTCCAAGAACTCATTCGTAAAAATATGGATAAGC...

CDS

2 records

下载 CDS FASTA

LOC131005174
ATGTTGCAGTTTTCGATCCAACGAGTGAGAGGCATGAGGAGGTTGAGTCCAGGAATATTTTGGGCTGCAAATTCTCGTCTCTCGACTGTTTCTGAACCATCTTCGAGGCCTGGCAACTCCCTGAGGATTCCGAATCTAATTGGAGGTAGGTTTGTAGACTCACATTCAACCGACTCCATTGATGTCATAAATCCGGCAACACAAGAGGTTGTTTCACAAGTGCCTCTGACAACAAAAGAGGAGTTCAAATCTGCAGTATC...

LOC131005174
ATGTTGAAGCTCCAAGAACTCATTCGTAAAAATATGGATAAGCTTGCCTTGAACATTACAACAGAACAAGGAAAAACACTGAAGGACGCTCAAGGAGATGTGTTCCGAGGGCTAGAGGTGGTGGAACATGCATGTGGCATGGCAACTCTACAGATGGGAGAGTATGTATCCAACGTGTCAAATGGAATCGATACCTATAGCATTAGAGAACCTCTTGGCGTTTGTGCTGGGATTTGCCCCTTTAACTTCCCTGCAATGAT...

Protein

2 records

下载 Protein FASTA

XP_057787987.1
MLQFSIQRVRGMRRLSPGIFWAANSRLSTVSEPSSRPGNSLRIPNLIGGRFVDSHSTDSIDVINPATQEVVSQVPLTTKEEFKSAVSAAKEAFPSWRNTPITTRQRVMLKLQELIRKNMDKLALNITTEQGKTLKDAQGDVFRGLEVVEHACGMATLQMGEYVSNVSNGIDTYSIREPLGVCAGICPFNFPAMIPLWMVPVAVTCGNTFVLKPSEKDPGASMILAELAMEAGLPDGVLNIVHGTNDTVNAICDDEDIRAV...

XP_057787988.1
MLKLQELIRKNMDKLALNITTEQGKTLKDAQGDVFRGLEVVEHACGMATLQMGEYVSNVSNGIDTYSIREPLGVCAGICPFNFPAMIPLWMVPVAVTCGNTFVLKPSEKDPGASMILAELAMEAGLPDGVLNIVHGTNDTVNAICDDEDIRAVSFVGSNTAGMHIYSRASASGKRVQSNMGAKNHGVVMPDANIDATLNALVAAGFGAAGQRCMALSTVVFVGDSKFWEEKIVERAKALKVSAGTDPEADLGPVISKQAK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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