Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G004858`

染色体: Chr01 坐标: 66740836-66743910 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G004858`
名称	SmilChr01G004858
描述	glutamyl-tRNA reductase 1, chloroplastic-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	66740836 - 66743910 / `-`

ID 对照

NCBI Gene ID	`LOC131005196`
GeneID	`131005196`
locus_tag	`-`
NCBI Name	`LOC131005196`
原始查询	`LOC131005196`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	glutamyl-tRNA reductase 1, chloroplastic-like
产物	glutamyl-tRNA reductase 1%2C chloroplastic-like
Arabidopsis	`AT1G58290` (HEMA1) Glutamyl-tRNA reductase family protein [Source:NCBI gene (formerly Entrezgene);Acc:842198] identity=69.8; qcov=0.865; evalue=0; confidence=high
Rice	`Os10g0502400` (HEMA1) - identity=65.2; qcov=0.833; evalue=0; confidence=high
GO	GO:0008883 (glutamyl-tRNA reductase activity); GO:0033014 (tetrapyrrole biosynthetic process); GO:0050661 (NADP binding)
KEGG	smil00860 (Porphyrin metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage))
Pfam	PF00745 (GlutR_dimer); PF01488 (Shikimate_DH); PF03807 (F420_oxidored); PF05201 (GlutR_N)
InterPro	-
eggNOG	-
NR	GeneID:131005196

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057788012.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057788012.1`
3	Nucleus	细胞核	0.00000	`XP_057788012.1`
4	Chromosome	染色体	0.00000	`XP_057788012.1`
5	Centromere	着丝粒	0.00000	`XP_057788012.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:66741312`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C68
`Chr1:66741411`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B108,B131,C2,C23
`Chr1:66741505`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B74
`Chr1:66742005`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B36,B64,B74,B78,C84
`Chr1:66742113`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C48
`Chr1:66742215`	`TC`	`T`	1bp_deletion	frameshift_variant	1	C9
`Chr1:66742215`	`TC`	`T`	1bp_deletion	CDS_variant	1	C9
`Chr1:66742272`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A19
`Chr1:66742636`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A19
`Chr1:66743708`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B4,C36,D6

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057788012.1

562 aa

281

562

GlutR_N

Shikimate_DH

F420_oxidored

GlutR_dimer

PF05201 GlutR_N 113-263 aa PF01488 Shikimate_DH 279-420 aa PF03807 F420_oxidored 296-365 aa PF00745 GlutR_dimer 434-538 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057788012.1`	Pfam	`PF05201`	GlutR_N	Domain	113	263	2.8e-49	167.5	Glutamyl-tRNAGlu reductase, N-terminal domain
`XP_057788012.1`	Pfam	`PF01488`	Shikimate_DH	Family	279	420	2.3e-39	135.3	Shikimate / quinate 5-dehydrogenase
`XP_057788012.1`	Pfam	`PF03807`	F420_oxidored	Family	296	365	1.4e-06	29.5	NADP oxidoreductase coenzyme F420-dependent
`XP_057788012.1`	Pfam	`PF00745`	GlutR_dimer	Domain	434	538	5.6e-28	97.9	Glutamyl-tRNAGlu reductase, dimerisation domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057932029.1
CAATTATGATGGACGCACCAAATCTCCATAACCCAATATTTGAGCAGTTGAAAATTTCGTTCAACCTTTACACCAAACCCCCCTCTCTTTCTTTCTCTCTCTCTGTCTCTGCCTGATTCCTTTCAATAAAACTCAGCTGCCCCAAGTCCTCCCTCCCTGCAAGCCTCCGTTCACCGGCACCAATGGCGGCGGCGAGCAGCTTCGTGATTTCCATCTCATCTGCCAACCGTGATGTTAATTCGGATACTAGATTGAAAATT...

CDS

1 records

下载 CDS FASTA

LOC131005196
ATGGCGGCGGCGAGCAGCTTCGTGATTTCCATCTCATCTGCCAACCGTGATGTTAATTCGGATACTAGATTGAAAATTGATCATTGCGGCAATGCCCAGCGTCTTCGTAATCTGTCGAGCTCTTCCATGCTTTGTTTTCCTCCGCGGATGCGAGGTCTTTTCAATGATTTGAGGTACAAGATTCCCGTGCCTGAAACGCTGTCGTTTAGATTGTGTCCGAGATGCGAGCTTGCTTCCGACTCGGAGATCCCCTCTAAATC...

Protein

1 records

下载 Protein FASTA

XP_057788012.1
MAAASSFVISISSANRDVNSDTRLKIDHCGNAQRLRNLSSSSMLCFPPRMRGLFNDLRYKIPVPETLSFRLCPRCELASDSEIPSKSSLSALELLKTSAADRYTKETSSLLVVGFNYRTAPIEIREKLSVPEAQWPQAIGELCALNHIEEAAVLSTCNRLEIYVVAMSQHRGIKEVTEWMSKISSVPVSELCQHRVLLFNKDATQHLFEVSSGLDSLVLGEGQILSQVKQVVKTGQGVPGFERKISGLFKHAITVGKRVR...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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