Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G004875`

染色体: Chr01 坐标: 66839456-66841540 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G004875`
名称	SmilChr01G004875
描述	malate dehydrogenase, glyoxysomal-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	66839456 - 66841540 / `-`

ID 对照

NCBI Gene ID	`LOC131005213`
GeneID	`131005213`
locus_tag	`-`
NCBI Name	`LOC131005213`
原始查询	`LOC131005213`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	malate dehydrogenase, glyoxysomal-like
产物	malate dehydrogenase%2C glyoxysomal-like
Arabidopsis	`AT2G22780` (PMDH1) peroxisomal NAD-malate dehydrogenase 1 [Source:NCBI gene (formerly Entrezgene);Acc:816808] identity=82.8; qcov=1.01; evalue=0; confidence=high
Rice	`Os12g0632700` - identity=83.8; qcov=0.989; evalue=0; confidence=high
GO	GO:0005737 (cytoplasm); GO:0006099 (tricarboxylic acid cycle); GO:0006108 (malate metabolic process); GO:0009507 (chloroplast); GO:0030060 (L-malate dehydrogenase (NAD+) activity)
KEGG	smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil00566 (Sulfoquinovose metabolism - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil00710 (Carbon fixation by Calvin cycle - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00056 (Ldh_1_N); PF02866 (Ldh_1_C)
InterPro	-
eggNOG	-
NR	GeneID:131005213

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057788035.1`
2	Cytoplasm	细胞质	0.60000	`XP_057788035.1`
3	Mitochondrion	线粒体	0.20000	`XP_057788035.1`
4	Nucleus	细胞核	0.00000	`XP_057788035.1`
5	Chromosome	染色体	0.00000	`XP_057788035.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:66839700`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A10,B52,B8,C84
`Chr1:66839855`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B88
`Chr1:66840743`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B107,B33,C22,C29
`Chr1:66840820`	`TGG`	`T`	2bp_deletion	frameshift_variant	1	B56
`Chr1:66840820`	`TGG`	`T`	2bp_deletion	CDS_variant	1	B56
`Chr1:66841003`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C48
`Chr1:66841221`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B78,B97,C2,C32,C68
`Chr1:66841226`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C9

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057788035.1

350 aa

175

350

Ldh_1_N

Ldh_1_C

PF00056 Ldh_1_N 40-182 aa PF02866 Ldh_1_C 184-347 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057788035.1`	Pfam	`PF00056`	Ldh_1_N	Domain	40	182	2.1e-45	154.9	lactate/malate dehydrogenase, NAD binding domain
`XP_057788035.1`	Pfam	`PF02866`	Ldh_1_C	Domain	184	347	1.2e-43	149.8	lactate/malate dehydrogenase, alpha/beta C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057932052.1
AAAAGAAGTGCCACCCAAAATAATTTAGAATTTTTAATTTTTGACACAGTTTTTGTGCGTTTAGCTTTGTGACAAAGGTCTGACATCAGAAAGGAGGCCTGTTTTCCTATGAAATACAAACAAATGGGAGAAGAAGAGCCAATCAAATACCCAATTTTGAGAGCCACAGACACTGGATACACAGATAAAGCCTCACTGAAAATTCCATTTCCATTCATATTCCGCACCTTAACCTTATAACTTCACACTCTTTCAAACAA...

CDS

1 records

下载 CDS FASTA

LOC131005213
ATGGAGGCCAACCACCGCATCTCCCGAATTTCGGCTCACCTCCATCCTTCAAATCCACAGATGGATCCCATGCTAAGGGCGGCGGAGTGCAGGGCCAAAGGCGGCGCCCCCGGCTTCAAAGTGGCCATATTGGGCGCCGCCGGAGGCATCGGGCAGCCCCTCTCCATGCTAATGAAGATGAACCCATTAGTCTCAGTTTTGCACCTATACGACGTCGTCAACGCCCCCGGCGTCACTGCCGATATCAGCCACATGGACAC...

Protein

1 records

下载 Protein FASTA

XP_057788035.1
MEANHRISRISAHLHPSNPQMDPMLRAAECRAKGGAPGFKVAILGAAGGIGQPLSMLMKMNPLVSVLHLYDVVNAPGVTADISHMDTGAVVRGFLGQPQLESALEGMDLVIIPAGVPRKPGMTRDDLFNINAGIVRTLCQGIAKSCPNAVVNLISNPVNSTVPIAAEVFKNAGIYDPKKLLGVTMLDVVRANTFVAEVLGLDPREVSVPVVGGHAGVTILPLLSQVKPPCSFTPEETEYLTKRIQDGGTEVVQAKAGAGS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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