Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G005634`

染色体: Chr01 坐标: 72779993-72785650 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G005634`
名称	SmilChr01G005634
描述	probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	72779993 - 72785650 / `+`

ID 对照

NCBI Gene ID	`LOC131005861`
GeneID	`131005861`
locus_tag	`-`
NCBI Name	`LOC131005861`
原始查询	`LOC131005861`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial
产物	probable phosphoribosylformylglycinamidine synthase%2C chloroplastic/mitochondrial
Arabidopsis	`AT1G74260` (PUR4) purine biosynthesis 4 [Source:NCBI gene (formerly Entrezgene);Acc:843766] identity=76.3; qcov=0.999; evalue=0; confidence=high
Rice	`Os05g0104650` - identity=75.9; qcov=0.957; evalue=0; confidence=high
GO	GO:0004642 (phosphoribosylformylglycinamidine synthase activity); GO:0006189 ('de novo' IMP biosynthetic process)
KEGG	smil00230 (Purine metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF02769 (AIRS_C); PF13507 (GATase_5); PF18072 (FGAR-AT_linker); PF18076 (FGAR-AT_N); PF22689 (FGAR-AT_PurM_N-like)
InterPro	-
eggNOG	-
NR	GeneID:131005861

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057788945.1`
2	Chloroplast stroma	叶绿体基质	0.40000	`XP_057788945.1`
3	Nucleus	细胞核	0.00000	`XP_057788945.1`
4	Chromosome	染色体	0.00000	`XP_057788945.1`
5	Centromere	着丝粒	0.00000	`XP_057788945.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:72780508`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A10,B104,B124
`Chr1:72780524`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B120,C21,C82
`Chr1:72780560`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B82
`Chr1:72780618`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B94
`Chr1:72780651`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B71
`Chr1:72780694`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B101,B133,B7,C34,C82
`Chr1:72780697`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B71,C62
`Chr1:72780714`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr1:72780780`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B112,C17
`Chr1:72780789`	`CT`	`C`	1bp_deletion	frameshift_variant	5	A5,B98,C27,C64,C66
`Chr1:72780789`	`CT`	`C`	1bp_deletion	CDS_variant	5	A5,B98,C27,C64,C66
`Chr1:72780852`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B65,B78,C18,D2

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057788945.1

1412 aa

706

1412

FGAR-AT_N

FGAR-AT_linker

AIRS_C

FGAR-AT_PurM_N-like

AIRS_C

GATase_5

PF18076 FGAR-AT_N 125-244 aa PF18072 FGAR-AT_linker 271-320 aa PF02769 AIRS_C 532-688 aa PF22689 FGAR-AT_PurM_N-like 759-911 aa PF02769 AIRS_C 943-1072 aa PF13507 GATase_5 1142-1411 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057788945.1`	Pfam	`PF18076`	FGAR-AT_N	Domain	125	244	4.3e-19	69.3	Formylglycinamide ribonucleotide amidotransferase N-terminal
`XP_057788945.1`	Pfam	`PF18072`	FGAR-AT_linker	Domain	271	320	2.1e-11	44.8	Formylglycinamide ribonucleotide amidotransferase linker domain
`XP_057788945.1`	Pfam	`PF02769`	AIRS_C	Domain	532	688	1.5e-49	168.8	AIR synthase related protein, C-terminal domain
`XP_057788945.1`	Pfam	`PF22689`	FGAR-AT_PurM_N-like	Domain	759	911	5e-52	176.6	FGAR-AT PurM_N-like domain
`XP_057788945.1`	Pfam	`PF02769`	AIRS_C	Domain	943	1072	1.5e-49	168.8	AIR synthase related protein, C-terminal domain
`XP_057788945.1`	Pfam	`PF13507`	GATase_5	Domain	1142	1411	2.5e-106	355.2	CobB/CobQ-like glutamine amidotransferase domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XR_009095365.1
AACCACTCTGTATTCGCGGCGCGAAAAAACTTCCCCCTCCCTGCCCGCCGCATCCTCTCGCCGCCCTCACGTCGCCGTCGTCGCGTCGAGCCACTGCCGGAAAACAGTTAAAAGCGCTGCCAACAGAGAGCAAGCAAGAGATACGGAGCGGCAATGGCTGCAGCTTTGGAGCTCACAGCTGCAGATTTTTTACAAGGTGCCTATAGGCAAAAACTAGCTTTGCCTAAACATTCCTTTAGGCAGACGGACTGCTTGCTTTG...

XM_057932962.1
CCACTCTGTATTCGCGGCGCGAAAAAACTTCCCCCTCCCTGCCCGCCGCATCCTCTCGCCGCCCTCACGTCGCCGTCGTCGCGTCGAGCCACTGCCGGAAAACAGTTAAAAGCGCTGCCAACAGAGAGCAAGCAAGAGATACGGAGCGGCAATGGCTGCAGCTTTGGAGCTCACAGCTGCAGATTTTTTACAAGGTGCCTATAGGCAAAAACTAGCTTTGCCTAAACATTCCTTTAGGCAGACGGACTGCTTGCTTTGGG...

CDS

1 records

下载 CDS FASTA

LOC131005861
ATGGCTGCAGCTTTGGAGCTCACAGCTGCAGATTTTTTACAAGGTGCCTATAGGCAAAAACTAGCTTTGCCTAAACATTCCTTTAGGCAGACGGACTGCTTGCTTTGGGGAACAAGGCTGCCGAGAAAACAGCCTTCTGTAAGAATTTCTCGTCGAGAAATTGCGTCGAGGCAATTGAAGGTGAAAGCGGTGGTCTCAAGGGATGTATGCAGTTCAGTAAGCGCGGAGGCCGATCAGCTTCAGAGGGCTTCTCAAGAGGT...

Protein

1 records

下载 Protein FASTA

XP_057788945.1
MAAALELTAADFLQGAYRQKLALPKHSFRQTDCLLWGTRLPRKQPSVRISRREIASRQLKVKAVVSRDVCSSVSAEADQLQRASQEVVHFYRIPLLQDNETAELLKLVQTKVSSQIVGLKTEQCFNIGVDGILSEDKVSALRWLLGETYEPDNLGAESFLDEEMKSSSNAVVVEVGPRLSFTTAWSSNAVSICRACNLTEISRLERSRRYLLCLAPGSASLVESQISEFAALVHDRMTECVYNQKLTSFERAVVPEEVRY...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

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