Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G000851`

染色体: Chr01 坐标: 18382740-18386363 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G000851`
名称	SmilChr01G000851
描述	E3 ubiquitin-protein ligase DIS1-like
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	18382740 - 18386363 / `-`

ID 对照

NCBI Gene ID	`LOC131006835`
GeneID	`131006835`
locus_tag	`-`
NCBI Name	`LOC131006835`
原始查询	`LOC131006835`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	E3 ubiquitin-protein ligase DIS1-like
产物	E3 ubiquitin-protein ligase DIS1-like
Arabidopsis	`AT3G61790` (AT3G61790) Protein with RING/U-box and TRAF-like domain [Source:NCBI gene (formerly Entrezgene);Acc:825352] identity=83.1; qcov=0.847; evalue=2.06e-169; confidence=high
Rice	`Os07g0659800` (P0496C02.112) - identity=86.3; qcov=0.974; evalue=0; confidence=high
GO	GO:0005515 (protein binding); GO:0005737 (cytoplasm); GO:0006511 (ubiquitin-dependent protein catabolic process); GO:0007275 (multicellular organism development); GO:0008270 (zinc ion binding); GO:0061630 (ubiquitin protein ligase activity)
KEGG	smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage))
Pfam	PF03145 (Sina_TRAF); PF21361 (Sina_ZnF); PF21362 (Sina_RING)
InterPro	-
eggNOG	-
NR	GeneID:131006835

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	0.60000	`XP_057789980.1`
2	Cytoplasm	细胞质	0.40000	`XP_057789980.1`
3	Cytoplasmic vesicle	细胞质囊泡	0.40000	`XP_057789980.1`
4	Autophagic vesicle	Autophagic vesicle	0.40000	`XP_057789980.1`
5	Autophagosome	Autophagosome	0.40000	`XP_057789980.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:18383032`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C35,D4
`Chr1:18383145`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B99,C17,C3,D8
`Chr1:18383596`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B104,B99,C17,C3,D8
`Chr1:18383683`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C87
`Chr1:18385159`	`AT`	`A`	1bp_deletion	frameshift_variant	2	A4,B104
`Chr1:18385159`	`AT`	`A`	1bp_deletion	CDS_variant	2	A4,B104

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057789980.1

318 aa

159

318

Sina_RING

Sina_ZnF

Sina_TRAF

PF21362 Sina_RING 70-105 aa PF21361 Sina_ZnF 119-194 aa PF03145 Sina_TRAF 214-311 aa

XP_057789981.1

308 aa

154

308

Sina_RING

Sina_ZnF

Sina_TRAF

PF21362 Sina_RING 60-95 aa PF21361 Sina_ZnF 109-184 aa PF03145 Sina_TRAF 204-301 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057789980.1`	Pfam	`PF21362`	Sina_RING	Domain	70	105	2.3e-13	50.8	E3 ubiquitin-protein ligase sina/sinah, RING finger
`XP_057789980.1`	Pfam	`PF21361`	Sina_ZnF	Domain	119	194	1.3e-29	103.1	Sina, zinc finger
`XP_057789980.1`	Pfam	`PF03145`	Sina_TRAF	Domain	214	311	7.5e-35	120.0	Sina, TRAF-like domain
`XP_057789981.1`	Pfam	`PF21362`	Sina_RING	Domain	60	95	2.2e-13	50.8	E3 ubiquitin-protein ligase sina/sinah, RING finger
`XP_057789981.1`	Pfam	`PF21361`	Sina_ZnF	Domain	109	184	1.2e-29	103.2	Sina, zinc finger
`XP_057789981.1`	Pfam	`PF03145`	Sina_TRAF	Domain	204	301	7e-35	120.1	Sina, TRAF-like domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057933998.1
TCCCCTCTTTCTCTCTCCGCGGCTTTAATTTGAATTGCAGTTTCTCTCTCTACTTCTCCTTTTCGTTTCCATTTTTTTTATGGTTACAAATTTATTTGTTGCTTGATTGCTTCACTATCCATTCCGTGCACTAGACCAAGACAAGAGACTTCTCTTACACACCTCTCTCTCCCTCTCCCTCTCTCGATATATTCACCAATTTCGTCGAATTCTCACAAAAAATTATCGTTGGTTGACTTTGCCGGATTATAAGTTACTAA...

XM_057933997.1
TTATTCTGGGTCTTTAAGTGTCTTATTTTCCTTTTCTTTTTCCTTATTCGCCCCTTTTTGGCAAAGGGCGAGTGTGGTGGAATATTCTGTATCTGCAATTTACTTTTGCTTTTGTAGTCTGCGTGATTTGGTGTTGGATGATTCATCTTTGCATGCTACTGAGTAAAATTTCTGAGATATTAATGTCGTCCATGTTAAATTTTATAAAGAAAGATTTCAAGATTATGTTTTTGTTGAATGTACAAAATTTAGTCTGATTC...

CDS

2 records

下载 CDS FASTA

LOC131006835
ATGCTTCACGCATGTGATGGCCCACCATACATGCTTCCGATGTCAAGTGGAAATTCCTACTATGATGACTTGCGAATGAAACCTGAGGTCATTGATCCACCTGAAAATGAAGACACATTGGACATTGGTGAGCATGTCAATGACACCTCAGAAAGTGCTTCAAAGCCTAATGTGGCTATTTCGACAAATGTCCGTGACCTGCTGGAGTGTCCTGTTTGCTTGAATGCTATGTACCCTCCAATTAGTCAGTGCTCCAACGG...

LOC131006835
ATGCTTCCGATGTCAAGTGGAAATTCCTACTATGATGACTTGCGAATGAAACCTGAGGTCATTGATCCACCTGAAAATGAAGACACATTGGACATTGGTGAGCATGTCAATGACACCTCAGAAAGTGCTTCAAAGCCTAATGTGGCTATTTCGACAAATGTCCGTGACCTGCTGGAGTGTCCTGTTTGCTTGAATGCTATGTACCCTCCAATTAGTCAGTGCTCCAACGGTCACACGTTATGTTCTGGTTGTAAACCCAG...

Protein

2 records

下载 Protein FASTA

XP_057789980.1
MLHACDGPPYMLPMSSGNSYYDDLRMKPEVIDPPENEDTLDIGEHVNDTSESASKPNVAISTNVRDLLECPVCLNAMYPPISQCSNGHTLCSGCKPRVHNRCPTCRHELGNIRCLALEKVAASLELPCKYQSFGCIGIYPYYSKLKHESQCTYRPYNCPYAGSECSVIGDIPFLVSHLKDDHKVDMHSGSTFNHRYVKSNPHEVENATWMLTVFSCFGQYFCLHFEAFQLGMAPVYIAFLRFMGDDNEAKNYSYSLEVGG...

XP_057789981.1
MLPMSSGNSYYDDLRMKPEVIDPPENEDTLDIGEHVNDTSESASKPNVAISTNVRDLLECPVCLNAMYPPISQCSNGHTLCSGCKPRVHNRCPTCRHELGNIRCLALEKVAASLELPCKYQSFGCIGIYPYYSKLKHESQCTYRPYNCPYAGSECSVIGDIPFLVSHLKDDHKVDMHSGSTFNHRYVKSNPHEVENATWMLTVFSCFGQYFCLHFEAFQLGMAPVYIAFLRFMGDDNEAKNYSYSLEVGGNGRKMIWQGV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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