Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr01G000024`

染色体: Chr01 坐标: 451046-452337 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr01G000024`
名称	SmilChr01G000024
描述	S-adenosylmethionine synthase 2
染色体 / SeqID	Chr01 / NC_080387.1
坐标与链方向	451046 - 452337 / `+`

ID 对照

NCBI Gene ID	`LOC131007166`
GeneID	`131007166`
locus_tag	`-`
NCBI Name	`LOC131007166`
原始查询	`LOC131007166`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	S-adenosylmethionine synthase 2
产物	S-adenosylmethionine synthase 2
Arabidopsis	`AT3G17390` (MTO3) S-adenosylmethionine synthetase family protein [Source:NCBI gene (formerly Entrezgene);Acc:821003] identity=93.8; qcov=0.992; evalue=0; confidence=high
Rice	`Os01g0293000` (OsSAMS3) - identity=93.6; qcov=0.997; evalue=0; confidence=high
GO	GO:0004478 (methionine adenosyltransferase activity); GO:0005524 (ATP binding); GO:0005829 (cytosol); GO:0006556 (S-adenosylmethionine biosynthetic process)
KEGG	smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil00670 (One carbon pool by folate - Salvia miltiorrhiza (redroot sage)); smil00999 (Biosynthesis of various plant secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage))
Pfam	PF00438 (S-AdoMet_synt_N); PF02772 (S-AdoMet_synt_M); PF02773 (S-AdoMet_synt_C)
InterPro	-
eggNOG	-
NR	GeneID:131007166

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057790314.1`
2	Cytosol	细胞质基质	1.00000	`XP_057790314.1`
3	Nucleus	细胞核	0.00000	`XP_057790314.1`
4	Chromosome	染色体	0.00000	`XP_057790314.1`
5	Centromere	着丝粒	0.00000	`XP_057790314.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr1:451403`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A11,C12,C58
`Chr1:451541`	`C`	`CAA`	2bp_insertion	frameshift_variant	2	A22,C77
`Chr1:451541`	`C`	`CAA`	2bp_insertion	CDS_variant	2	A22,C77
`Chr1:451543`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C2,C8
`Chr1:451603`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B106,B11,C27,C41
`Chr1:451834`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B41,C44
`Chr1:451891`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B55,C13,C2,C8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057790314.1

390 aa

195

390

S-AdoMet_synt_N

S-AdoMet_synt_M

S-AdoMet_synt_C

PF00438 S-AdoMet_synt_N 4-101 aa PF02772 S-AdoMet_synt_M 117-238 aa PF02773 S-AdoMet_synt_C 240-381 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057790314.1`	Pfam	`PF00438`	S-AdoMet_synt_N	Domain	4	101	4.7e-43	146.5	S-adenosylmethionine synthetase, N-terminal domain
`XP_057790314.1`	Pfam	`PF02772`	S-AdoMet_synt_M	Domain	117	238	1.6e-48	164.5	S-adenosylmethionine synthetase, central domain
`XP_057790314.1`	Pfam	`PF02773`	S-AdoMet_synt_C	Domain	240	381	1.7e-61	206.9	S-adenosylmethionine synthetase, C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057934331.1
ATGGAGACCTTCCTGTTTACATCTGAGTCTGTGAACGAGGGGCACCCCGACAAGCTGTGTGATCAGATCTCCGATGCAGTGCTGGACGCTTGCCTGGCTGATGACCCCGAGAGCAAGGTTGCCTGTGAGACATGCACCAAGACGAATATGGTGATGGTCTTTGGAGAGATCACCACCAAGGCTAATGTTGACTACGAGAAGATTGTCCGTGACACATGCCGTGCTATTGGATTTATTTCGGACGATGTAGGTCTCGATGC...

CDS

1 records

下载 CDS FASTA

LOC131007166
ATGGAGACCTTCCTGTTTACATCTGAGTCTGTGAACGAGGGGCACCCCGACAAGCTGTGTGATCAGATCTCCGATGCAGTGCTGGACGCTTGCCTGGCTGATGACCCCGAGAGCAAGGTTGCCTGTGAGACATGCACCAAGACGAATATGGTGATGGTCTTTGGAGAGATCACCACCAAGGCTAATGTTGACTACGAGAAGATTGTCCGTGACACATGCCGTGCTATTGGATTTATTTCGGACGATGTAGGTCTCGATGC...

Protein

1 records

下载 Protein FASTA

XP_057790314.1
METFLFTSESVNEGHPDKLCDQISDAVLDACLADDPESKVACETCTKTNMVMVFGEITTKANVDYEKIVRDTCRAIGFISDDVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKQPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYYNDNGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYG...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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