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中文 EN

Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。
示例

当前解析结果

SmilChr02G004478

染色体: Chr02 坐标: 67185667-67195189 链方向: - 类型: protein_coding

基本信息

统一新 Gene IDSmilChr02G004478
名称SmilChr02G004478
描述protein TOPLESS
染色体 / SeqIDChr02 / NC_080388.1
坐标与链方向67185667 - 67195189 / -

ID 对照

NCBI Gene IDLOC131007754
GeneID131007754
locus_tag-
NCBI NameLOC131007754
原始查询LOC131007754

查看完整 ID 对照表

功能注释

来源GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述protein TOPLESS
产物protein TOPLESS
ArabidopsisAT1G15750 (TPL)
Transducin family protein / WD-40 repeat family protein [Source:NCBI gene (formerly Entrezgene);Acc:838144]
identity=83.8; qcov=1.01; evalue=0; confidence=high
RiceOs03g0254700 (OsWD40-66)
protein TPR3-like [Source:NCBI gene (formerly Entrezgene);Acc:4332285]
identity=80.8; qcov=1.01; evalue=0; confidence=high
GOGO:0005515 (protein binding); GO:0006355 (regulation of DNA-templated transcription)
KEGG-
PfamPF00400 (WD40); PF17814 (LisH_TPL); PF21359 (zf_topless); PF21889 (TPR1-like_2nd)
InterPro-
eggNOG-
NRGeneID:131007754

打开注释模块

亚细胞定位 Top 5

Rank定位位置中文ScoreProtein ID
1 Nucleus 细胞核 1.00000 XP_057790640.1
2 Chromosome 染色体 0.00000 XP_057790640.1
3 Centromere 着丝粒 0.00000 XP_057790640.1
4 Chromatin 染色质 0.00000 XP_057790640.1
5 Telomere 端粒 0.00000 XP_057790640.1

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置 REF ALT 类型 影响 携带材料数 材料
Chr2:67186022 G A EMS_canonical_SNV stop_gained 1 B97
Chr2:67186022 G A EMS_canonical_SNV CDS_variant 1 B97
Chr2:67186410 G A EMS_canonical_SNV CDS_variant 1 B140
Chr2:67186630 C T EMS_canonical_SNV CDS_variant 1 C48
Chr2:67187071 G A EMS_canonical_SNV CDS_variant 5 B12,B130,B36,B82,B86
Chr2:67187709 CT C 1bp_deletion frameshift_variant 1 B39
Chr2:67189675 G A EMS_canonical_SNV CDS_variant 1 D10
Chr2:67190149 G A EMS_canonical_SNV CDS_variant 2 B16,B26
Chr2:67190961 G A EMS_canonical_SNV CDS_variant 2 B16,C36
Chr2:67191261 C CTG 2bp_insertion frameshift_variant 1 B122
Chr2:67191261 C CTG 2bp_insertion CDS_variant 1 B122
Chr2:67191488 G A EMS_canonical_SNV CDS_variant 1 D11

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057790640.1
1132 aa
N
1
566
1132
LisH_TPL
TPR1-like_2nd
zf_topless
WD40
WD40
WD40
C
PF17814 LisH_TPL 5-34 aa PF21889 TPR1-like_2nd 37-161 aa PF21359 zf_topless 164-204 aa PF00400 WD40 456-490 aa PF00400 WD40 495-533 aa PF00400 WD40 913-948 aa
XP_057790641.1
1131 aa
N
1
566
1131
LisH_TPL
TPR1-like_2nd
zf_topless
WD40
WD40
WD40
C
PF17814 LisH_TPL 5-34 aa PF21889 TPR1-like_2nd 37-161 aa PF21359 zf_topless 164-204 aa PF00400 WD40 456-490 aa PF00400 WD40 495-533 aa PF00400 WD40 913-948 aa
XP_057790642.1
1131 aa
N
1
566
1131
LisH_TPL
TPR1-like_2nd
zf_topless
WD40
WD40
WD40
C
PF17814 LisH_TPL 5-34 aa PF21889 TPR1-like_2nd 37-161 aa PF21359 zf_topless 164-204 aa PF00400 WD40 456-490 aa PF00400 WD40 495-533 aa PF00400 WD40 913-948 aa
Protein ID 来源 结构域编号 结构域名称 类型 起始 aa 终止 aa E-value Score 说明
XP_057790640.1 Pfam PF17814 LisH_TPL Domain 5 34 4.1e-13 49.4 LisH-like dimerisation domain
XP_057790640.1 Pfam PF21889 TPR1-like_2nd Domain 37 161 1.2e-63 213.7 TPR1-like, CTLH-containing domain
XP_057790640.1 Pfam PF21359 zf_topless Domain 164 204 6.8e-25 87.1 TOPLESS, zinc finger domain
XP_057790640.1 Pfam PF00400 WD40 Repeat 456 490 2.1e-35 120.4 WD domain, G-beta repeat
XP_057790640.1 Pfam PF00400 WD40 Repeat 495 533 2.1e-35 120.4 WD domain, G-beta repeat
XP_057790640.1 Pfam PF00400 WD40 Repeat 913 948 2.1e-35 120.4 WD domain, G-beta repeat
XP_057790641.1 Pfam PF17814 LisH_TPL Domain 5 34 4.1e-13 49.4 LisH-like dimerisation domain
XP_057790641.1 Pfam PF21889 TPR1-like_2nd Domain 37 161 1.2e-63 213.7 TPR1-like, CTLH-containing domain
XP_057790641.1 Pfam PF21359 zf_topless Domain 164 204 6.8e-25 87.1 TOPLESS, zinc finger domain
XP_057790641.1 Pfam PF00400 WD40 Repeat 456 490 4.5e-36 122.5 WD domain, G-beta repeat
XP_057790641.1 Pfam PF00400 WD40 Repeat 495 533 4.5e-36 122.5 WD domain, G-beta repeat
XP_057790641.1 Pfam PF00400 WD40 Repeat 913 948 4.5e-36 122.5 WD domain, G-beta repeat
XP_057790642.1 Pfam PF17814 LisH_TPL Domain 5 34 4.1e-13 49.4 LisH-like dimerisation domain
XP_057790642.1 Pfam PF21889 TPR1-like_2nd Domain 37 161 1.2e-63 213.7 TPR1-like, CTLH-containing domain
XP_057790642.1 Pfam PF21359 zf_topless Domain 164 204 6.8e-25 87.1 TOPLESS, zinc finger domain
XP_057790642.1 Pfam PF00400 WD40 Repeat 456 490 4.5e-36 122.5 WD domain, G-beta repeat
XP_057790642.1 Pfam PF00400 WD40 Repeat 495 533 4.5e-36 122.5 WD domain, G-beta repeat
XP_057790642.1 Pfam PF00400 WD40 Repeat 913 948 4.5e-36 122.5 WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA
XM_057934658.1
TTGACTGTACATATGATAAATATTATATTCCCACCAAATGATAACCTACTCTACTTATCGTTGTTTCCGAAATGATACGTAAGCTTACTTATCTCCTTCACTGACTCGCCCCTTCCTATAAAAATCACTTATTTTCTGCAAGTAATGTCGTAGTTTATTTTTTTTCCTTTCCCCAACGATAGACTAGAGAGAGAAAGTAGAGAGAGAAAGGAACTCCCATGTGTCTCTAGTTCTATACACAATCTCTCACCTCATAGAGA...
XM_057934657.1
TTGACTGTACATATGATAAATATTATATTCCCACCAAATGATAACCTACTCTACTTATCGTTGTTTCCGAAATGATACGTAAGCTTACTTATCTCCTTCACTGACTCGCCCCTTCCTATAAAAATCACTTATTTTCTGCAAGTAATGTCGTAGTTTATTTTTTTTCCTTTCCCCAACGATAGACTAGAGAGAGAAAGTAGAGAGAGAAAGGAACTCCCATGTGTCTCTAGTTCTATACACAATCTCTCACCTCATAGAGA...

CDS

3 records

下载 CDS FASTA
LOC131007754
ATGTCTTCTCTCAGTAGAGAACTGGTGTTCTTGATCTTACAGTTCCTAGATGAAGAGAAGTTCAAAGAGACCGTTCACAAGCTTGAGCAAGAATCTGGATTCTTCTTTAACATGAAGTATTTTGAAGATGAAGTTCACAATGGGAACTGGGAGGAGGTTGAAAAATACCTCTCTGGCTTCACTAAAGTAGACGACAATCGCTATTCTATGAAGATCTTTTTTGAGATTAGGAAGCAGAAGTACCTTGAAGCATTGGATAA...
LOC131007754
ATGTCTTCTCTCAGTAGAGAACTGGTGTTCTTGATCTTACAGTTCCTAGATGAAGAGAAGTTCAAAGAGACCGTTCACAAGCTTGAGCAAGAATCTGGATTCTTCTTTAACATGAAGTATTTTGAAGATGAAGTTCACAATGGGAACTGGGAGGAGGTTGAAAAATACCTCTCTGGCTTCACTAAAGTAGACGACAATCGCTATTCTATGAAGATCTTTTTTGAGATTAGGAAGCAGAAGTACCTTGAAGCATTGGATAA...

Protein

3 records

下载 Protein FASTA
XP_057790640.1
MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEDEVHNGNWEEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDKHDRSKAVEILVKDLKVFASFNEELFKEITQLLTLENFRENEQLSKYGDTKSARAIMLVELKKLIEANPLFRDKLQFPNLKNSRLRTLINQSLNWQHQLCKNPRPNPDIKTLFVDHSCGQPNGARAPSPANNPLLGGAVPKPGGFPPLGAHVPFQPSPAPVPTPLAGWMSNPPT...
XP_057790641.1
MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEDEVHNGNWEEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDKHDRSKAVEILVKDLKVFASFNEELFKEITQLLTLENFRENEQLSKYGDTKSARAIMLVELKKLIEANPLFRDKLQFPNLKNSRLRTLINQSLNWQHQLCKNPRPNPDIKTLFVDHSCGQPNGARAPSPANNPLLGGAVPKPGGFPPLGAHVPFQPSPAPVPTPLAGWMSNPPT...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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