Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004869`

染色体: Chr02 坐标: 70789216-70791726 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004869`
名称	SmilChr02G004869
描述	MDIS1-interacting receptor like kinase 2-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	70789216 - 70791726 / `+`

ID 对照

NCBI Gene ID	`LOC131008866`
GeneID	`131008866`
locus_tag	`-`
NCBI Name	`LOC131008866`
原始查询	`LOC131008866`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	MDIS1-interacting receptor like kinase 2-like
产物	MDIS1-interacting receptor like kinase 2-like
Arabidopsis	`AT4G08850` (AT4G08850) Leucine-rich repeat receptor-like protein kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:826456] identity=40.9; qcov=0.867; evalue=9.48e-152; confidence=medium
Rice	`Os02g0553000` - identity=39; qcov=0.876; evalue=1.99e-136; confidence=medium
GO	GO:0004672 (protein kinase activity); GO:0005515 (protein binding); GO:0005524 (ATP binding); GO:0006468 (protein phosphorylation)
KEGG	-
Pfam	PF00069 (Pkinase); PF00560 (LRR_1); PF07714 (PK_Tyr_Ser-Thr); PF13516 (LRR_6); PF13855 (LRR_8); PF23598 (LRR_14)
InterPro	-
eggNOG	-
NR	GeneID:131008866

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057791945.1`
2	Nucleus	细胞核	0.00000	`XP_057791945.1`
3	Chromosome	染色体	0.00000	`XP_057791945.1`
4	Centromere	着丝粒	0.00000	`XP_057791945.1`
5	Chromatin	染色质	0.00000	`XP_057791945.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:70789275`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr2:70789380`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A7,C79,C85
`Chr2:70789453`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C33,D1
`Chr2:70789578`	`GAT`	`G`	2bp_deletion	frameshift_variant	19	A1,A13,A16,B117,B34,B42,B43,B48,B57,B58,B82,B88,C15,C20,C26,C27,C53,C57,D2
`Chr2:70789593`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D1
`Chr2:70789597`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C65
`Chr2:70789606`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr2:70789635`	`TGA`	`T`	2bp_deletion	frameshift_variant	49	A15,A16,A5,B10,B100,B103,B129,B132,B14,B21,B34,B37,B4,B42,B43,B44,B45,B54,B57,B58,B64,B65,B67,B70,B78,B8,B80,B82,B84,B88,B98,C15,C16,C26,C30,C33,C35,C4,C5,C56,C58,C67,C7,C72,C74,C75,C86,D1,D3
`Chr2:70789690`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A6,C35,C65
`Chr2:70789771`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A6,C43,C65
`Chr2:70789819`	`C`	`CAT`	2bp_insertion	frameshift_variant	4	A13,B127,C43,C8
`Chr2:70789819`	`C`	`CAT`	2bp_insertion	CDS_variant	4	A13,B127,C43,C8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057791945.1

720 aa

360

720

LRR_8

LRR_1

LRR_6

LRR_1

LRR_14

LRR_8

LRR_1

LRR_6

LRR_1

PK_Tyr_Ser-Thr

Pkinase

PF13855 LRR_8 83-141 aa PF00560 LRR_1 84-106 aa PF13516 LRR_6 107-122 aa PF00560 LRR_1 108-130 aa PF00560 LRR_1 132-155 aa PF00560 LRR_1 157-179 aa PF23598 LRR_14 176-304 aa PF13855 LRR_8 180-240 aa PF00560 LRR_1 181-203 aa PF13516 LRR_6 203-218 aa PF00560 LRR_1 205-227 aa PF00560 LRR_1 300-320 aa PF07714 PK_Tyr_Ser-Thr 428-697 aa PF00069 Pkinase 429-695 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057791945.1`	Pfam	`PF13855`	LRR_8	Repeat	83	141	3e-26	91.7	Leucine rich repeat
`XP_057791945.1`	Pfam	`PF00560`	LRR_1	Repeat	84	106	1.5e-31	102.3	Leucine Rich Repeat
`XP_057791945.1`	Pfam	`PF13516`	LRR_6	Repeat	107	122	5.3e-10	39.3	Leucine Rich repeat
`XP_057791945.1`	Pfam	`PF00560`	LRR_1	Repeat	108	130	1.5e-31	102.3	Leucine Rich Repeat
`XP_057791945.1`	Pfam	`PF00560`	LRR_1	Repeat	132	155	1.5e-31	102.3	Leucine Rich Repeat
`XP_057791945.1`	Pfam	`PF00560`	LRR_1	Repeat	157	179	1.5e-31	102.3	Leucine Rich Repeat
`XP_057791945.1`	Pfam	`PF23598`	LRR_14	Repeat	176	304	9e-19	68.1	Leucine-rich repeat region
`XP_057791945.1`	Pfam	`PF13855`	LRR_8	Repeat	180	240	3e-26	91.7	Leucine rich repeat
`XP_057791945.1`	Pfam	`PF00560`	LRR_1	Repeat	181	203	1.5e-31	102.3	Leucine Rich Repeat
`XP_057791945.1`	Pfam	`PF13516`	LRR_6	Repeat	203	218	5.3e-10	39.3	Leucine Rich repeat
`XP_057791945.1`	Pfam	`PF00560`	LRR_1	Repeat	205	227	1.5e-31	102.3	Leucine Rich Repeat
`XP_057791945.1`	Pfam	`PF00560`	LRR_1	Repeat	300	320	1.5e-31	102.3	Leucine Rich Repeat
`XP_057791945.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	428	697	9.7e-43	147.0	Protein tyrosine and serine/threonine kinase
`XP_057791945.1`	Pfam	`PF00069`	Pkinase	Domain	429	695	3.6e-46	158.4	Protein kinase domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057935962.1
GAGTATCATAACAGAAGGAATCATGCATATCCTCACAAATACGAACTAGATATAAAAATGAGGGATTTTGGGATTACGACTCGCGTTTTGATCATCGCCATAGTGATGATCAAAGCAGCAGAAGCAAGCAGGAGCAGCGAAATGCAGGCATTGATGAAATTTGGGTGGCCACGTGATGATATCAACTCCACTACTCATCACTGCAACTGGACCGGCATTACTTGTGATGATGCTGGCCATATCAACGCTCTACTTCTCTC...

CDS

1 records

下载 CDS FASTA

LOC131008866
ATGAGGGATTTTGGGATTACGACTCGCGTTTTGATCATCGCCATAGTGATGATCAAAGCAGCAGAAGCAAGCAGGAGCAGCGAAATGCAGGCATTGATGAAATTTGGGTGGCCACGTGATGATATCAACTCCACTACTCATCACTGCAACTGGACCGGCATTACTTGTGATGATGCTGGCCATATCAACGCTCTACTTCTCTCTCATACTACTCTTAGTTTTAAGTATTTTGATGTGTTTGCTTTTCCACATCTCACTAG...

Protein

1 records

下载 Protein FASTA

XP_057791945.1
MRDFGITTRVLIIAIVMIKAAEASRSSEMQALMKFGWPRDDINSTTHHCNWTGITCDDAGHINALLLSHTTLSFKYFDVFAFPHLTRINLTFCRLNGTIPPQIGSLSKLTHLDLSHNKLNGEMPLSLSNLTNLQVLDISHNYYISGVIPPEIASLSKLTHLDLSNNALYTHLPLSLANLTNLRLLDISHNRVSGVIPPGIGYLQHLIVLDLSRNRISGSLPSTMSQLTRLELLKLEGNMLRGVFEAGIQKLPSIKTISLS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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