Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G005236`

染色体: Chr02 坐标: 73550427-73555379 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G005236`
名称	SmilChr02G005236
描述	protein TPX2
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	73550427 - 73555379 / `+`

ID 对照

NCBI Gene ID	`LOC131009200`
GeneID	`131009200`
locus_tag	`-`
NCBI Name	`LOC131009200`
原始查询	`LOC131009200`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	protein TPX2
产物	protein TPX2
Arabidopsis	`AT1G03780` (TPX2) targeting protein for XKLP2 [Source:NCBI gene (formerly Entrezgene);Acc:839140] identity=57.2; qcov=1.02; evalue=0; confidence=high
Rice	`Os07g0507200` (OSJNBb0062D12.128) - identity=38.9; qcov=0.58; evalue=1.29e-83; confidence=medium
GO	GO:0005880 (nuclear microtubule); GO:0008017 (microtubule binding); GO:0030295 (protein kinase activator activity); GO:0032147 (activation of protein kinase activity); GO:0060236 (regulation of mitotic spindle organization); GO:0072686 (mitotic spindle); GO:0090307 (mitotic spindle assembly)
KEGG	-
Pfam	PF06886 (TPX2); PF12214 (TPX2_importin)
InterPro	-
eggNOG	-
NR	GeneID:131009200

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoskeleton	细胞骨架	1.00000	`XP_057792436.1`
2	Spindle	Spindle	1.00000	`XP_057792436.1`
3	Spindle pole	Spindle pole	1.00000	`XP_057792436.1`
4	Centrosome	中心体	0.60000	`XP_057792436.1`
5	Chromosome	染色体	0.20000	`XP_057792436.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:73550643`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr2:73550782`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B100
`Chr2:73550788`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B100,B131
`Chr2:73551566`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C13,D4
`Chr2:73551733`	`A`	`ATC`	2bp_insertion	frameshift_variant	187	A1,A13,A16,A18,A2,A20,A21,A22,A23,A24,A25,A3,A4,A8,A9,B1,B10,B100,B102,B104,B105,B107,B11,B110,B111,B112,B113,B114,B117,B118,B119,B12,B120,B121,B123,B124,B125,B126,B128,B129,B13,B130,B131,B132,B135,B136,B137,B139,B140,B15,B17,B18,B19,B2,B20,B21,B22,B24,B25,B26,B27,B28,B30,B32,B33,B34,B35,B36,B37,B38,B39,B4,B42,B43,B46,B48,B50,B51,B53,B56,B59,B6,B61,B64,B66,B67,B7,B70,B71,B72,B73,B74,B75,B77,B79,B8,B80,B82,B84,B85,B86,B90,B92,B93,B94,B95,B96,B97,B98,B99,C1,C10,C11,C12,C13,C14,C15,C17,C18,C19,C22,C24,C25,C26,C28,C29,C3,C30,C32,C33,C35,C36,C37,C38,C39,C4,C40,C41,C42,C44,C46,C48,C49,C5,C50,C51,C52,C53,C54,C55,C56,C57,C59,C6,C60,C61,C63,C65,C68,C69,C70,C71,C72,C74,C75,C76,C77,C78,C79,C80,C81,C82,C84,C85,C86,C87,C9,D1,D10,D2,D3,D4,D5,D6,D7,D8,D9
`Chr2:73551815`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C13,D4
`Chr2:73552103`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A11,B63,B88,C27
`Chr2:73552231`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr2:73552379`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B2,B33,B37,B64,B68
`Chr2:73552751`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B64
`Chr2:73553276`	`CA`	`C`	1bp_deletion	frameshift_variant	1	C45
`Chr2:73553276`	`CA`	`C`	1bp_deletion	CDS_variant	1	C45

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057792436.1

783 aa

392

783

TPX2_importin

TPX2

PF12214 TPX2_importin 342-434 aa PF12214 TPX2_importin 444-492 aa PF12214 TPX2_importin 478-515 aa PF06886 TPX2 675-751 aa

XP_057792437.1

781 aa

390

781

TPX2_importin

TPX2

PF12214 TPX2_importin 342-432 aa PF12214 TPX2_importin 442-490 aa PF12214 TPX2_importin 476-513 aa PF06886 TPX2 673-749 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057792436.1`	Pfam	`PF12214`	TPX2_importin	Family	342	434	1.2e-50	172.1	Cell cycle regulated microtubule associated protein
`XP_057792436.1`	Pfam	`PF12214`	TPX2_importin	Family	444	492	1.2e-50	172.1	Cell cycle regulated microtubule associated protein
`XP_057792436.1`	Pfam	`PF12214`	TPX2_importin	Family	478	515	1.2e-50	172.1	Cell cycle regulated microtubule associated protein
`XP_057792436.1`	Pfam	`PF06886`	TPX2	Domain	675	751	5.8e-22	78.2	Targeting protein for Xklp2 (TPX2) domain
`XP_057792437.1`	Pfam	`PF12214`	TPX2_importin	Family	342	432	1.2e-50	172.1	Cell cycle regulated microtubule associated protein
`XP_057792437.1`	Pfam	`PF12214`	TPX2_importin	Family	442	490	1.2e-50	172.1	Cell cycle regulated microtubule associated protein
`XP_057792437.1`	Pfam	`PF12214`	TPX2_importin	Family	476	513	1.2e-50	172.1	Cell cycle regulated microtubule associated protein
`XP_057792437.1`	Pfam	`PF06886`	TPX2	Domain	673	749	5.8e-22	78.2	Targeting protein for Xklp2 (TPX2) domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057936453.1
CGACCGTTAAACAGAATCCGACCGTTAATATCCCTCCCTCTCTTCTCTCTCTCTCTCCCTAAACAACACAACGCAGCGCCATCTTCTCTTGCAAGATCATATCTTTTGCGCTCTTCTTCTTCTTCTCCCCTACTCATCGAATACAGCTTTTCCCCACACTCTAGGAATTACCGGAATATTTGGTTGTTCGATTGATTATTCCCGATTGAATGGCGGCGGTGGAGGAGTCCAGTAGTAGTAGTCTATTCATGGTCGATGAG...

XM_057936454.1
CGACCGTTAAACAGAATCCGACCGTTAATATCCCTCCCTCTCTTCTCTCTCTCTCTCCCTAAACAACACAACGCAGCGCCATCTTCTCTTGCAAGATCATATCTTTTGCGCTCTTCTTCTTCTTCTCCCCTACTCATCGAATACAGCTTTTCCCCACACTCTAGGAATTACCGGAATATTTGGTTGTTCGATTGATTATTCCCGATTGAATGGCGGCGGTGGAGGAGTCCAGTAGTAGTAGTCTATTCATGGTCGATGAG...

CDS

2 records

下载 CDS FASTA

LOC131009200
ATGGCGGCGGTGGAGGAGTCCAGTAGTAGTAGTCTATTCATGGTCGATGAGGCGTACGAGTTCTCGGCGCCGCGATTTCACGATTTCATGACGGAGGAGACTGCCGAGGAAGTTCGTAGGGCGGAGCTCTGGTTCGAGAGCGCCCTCACTCACGCCCCTTCTCCATTTATGCCTAGAATCAGAGCTACCAGAACAGGTCAACAGATTCTTTGCAGTTTCAATGAAGACGAGCACATGCAGAAGGCGCCGAAATCATCTGA...

Protein

2 records

下载 Protein FASTA

XP_057792436.1
MAAVEESSSSSLFMVDEAYEFSAPRFHDFMTEETAEEVRRAELWFESALTHAPSPFMPRIRATRTGQQILCSFNEDEHMQKAPKSSENAPNASNSAEELAPKSLNQILQANSAETTQEVRTRIIPKEIEKTPAAESSCSQEKENIAQGGEAPSSVPKEAAAVQGPEVCCTPAPQKQRDDRKLQTSKKIASMLKNPSAINSKKQLPKSQSKSAKPASVRRDTNGNKNIVGTPNFAHENHAIKKQKLDGGKSRQILTVNKPS...

XP_057792437.1
MAAVEESSSSSLFMVDEAYEFSAPRFHDFMTEETAEEVRRAELWFESALTHAPSPFMPRIRATRTGQQILCSFNEDEHMQKAPKSSENAPNASNSAEELAPKSLNQILQANSAETTQEVRTRIIPKEIEKTPAAESSCSQEKENIAQGGEAPSSVPKEAAAVQGPEVCCTPAPQKQRDDRKLQTSKKIASMLKNPSAINSKKQLPKSQSKSAKPASVRRDTNGNKNIVGTPNFAHENHAIKKQKLDGGKSRQILTVNKPS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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